Hematologic Neoplasms
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-07-16EMA Authorised: Zemcelpro (allogeneic umbilical cord-derived CD34- cells, non-expanded;dorocubicel) — Cordex Biologics International Limited
EMA has authorised Zemcelpro (allogeneic umbilical cord-derived CD34- cells, non-expanded; dorocubicel) for hematologic neoplasms and hemato…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies [Phase 1]
Phase 1 clinical trial evaluating autologous T cells engineered with retroviral vectors to express TCRs against patient-specific neoantigens…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members
This clinical trial update describes the collection of tissue specimens from patients with solid tumors or hematologic neoplasms and their H…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Cognitive Training Intervention and Attitudes Towards Genetics [NA]
Clinical trial update for a University of Alabama at Birmingham study evaluating a cognitive training intervention and attitudes toward gene…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: LLM-Generated Plain-Language Patient Synopses to Improve Comprehension in Hematology and Oncology (oncOPAL) [NA]
This clinical trial from Technical University of Munich is testing whether large-language model–generated plain-language patient synopses im…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Mind-body Medicine for Patients With Malignant Hematological Diseases [NA]
A clinical trial evaluating mind-body medicine for patients with malignant hematologic diseases is currently recruiting, sponsored by Univer…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies [Phase 1, Phase 2]
Phase I/II clinical trial sponsored by the National Cancer Institute to reduce post-transplant cyclophosphamide dosing in older or unfit pat…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Influenza Vaccination Strategy for Patients With Hematologic Malignancy [Phase 3]
A Phase 3 clinical trial update evaluating an influenza vaccination strategy in patients with hematologic neoplasms; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Study of AZD2962, an IRAK4 Inhibitor (IRAK4 [a Body Protein] Blocker), in Participants With Haematologic Neoplasms (Blood Cancers) [Phase 1]
This clinical trial update describes a Phase 1 study of AZD2962, an IRAK4 inhibitor, in participants with hematologic neoplasms, currently r…
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CLINICAL_TRIALS withdrawal · 2026-02-24Clinical Trial Update: A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell Transplantation [Phase 2]
Phase 2 trial of ASTX727 (oral decitabine/cedazuridine) for hematologic neoplasms after allogeneic stem cell transplantation has been withdr…
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CLINICAL_TRIALS other · 2026-02-23Clinical Trial Update: Pre-myeloid Cancer and Bone Marrow Failure Clinic Study [NA]
A Mayo Clinic clinical trial update for a study addressing pre-myeloid cancer and inherited bone marrow failure syndromes, currently recruit…
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EMA approval · 2026-02-18EMA Authorised: Zemcelpro (allogeneic umbilical cord-derived CD34- cells, non-expanded;dorocubicel) — Cordex Biologics International Limited
EMA authorized Zemcelpro, an allogeneic cord-derived CD34- cell therapy (dorocubicel), for hematologic neoplasms and hematopoietic stem cell…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Research Development13(RD13)-02 Cell Injection in Patients With Relapsed or Refractory Cluster Of Differentiation 7(CD7)-Positive Hematological Malignancies [EARLY_Phase 1]
An early-phase 1 study investigating a cell injection therapy for relapsed or refractory CD7-positive hematologic malignancies has completed…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating donor lymphocyte infusion after allogeneic hematopoietic cell transplantation in patients with high…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation [Phase 1]
A Phase I trial is evaluating the integration of HLA-haploidentical anti-CD19 CAR-T cells with post-transplant cyclophosphamide-based haploi…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Bendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating bendamustine with or without cyclophosphamide to prevent graft-versus-host disease in patients undergo…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating fecal microbiota transplantation to prevent acute graft-versus-host disease in adults undergoing allogenei…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Platelet Transfusions in Hematopoietic Stem Cell Transplantation (The PATH III Trial) [Phase 3]
The PATH III trial is a Phase 3 study evaluating platelet transfusions in hematopoietic stem cell transplantation and is currently recruitin…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Comparison of Hemanext ONE® System and Conventional Red Blood Cell Transfusion [NA]
Clinical trial comparing the Hemanext ONE System to conventional red blood cell transfusion; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Optimizing PTCy Dose and Timing [Phase 1, Phase 2]
This clinical trial update describes an ongoing Phase 1/2 study aiming to optimize the dose and timing of post-transplant cyclophosphamide t…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial is evaluating ibrutinib for prevention of chronic graft-versus-host disease in patients receiving donor stem cell t…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil [Phase 2]
Phase 2 trial evaluating fludarabine with total body irradiation and post-transplant cyclophosphamide/tacrolimus GVHD prophylaxis (without m…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Gardasil 9 Vaccine in Preventing HPV Infection in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 4]
Phase 4 clinical trial update indicating Gardasil 9 is being studied to prevent HPV infection in patients with hematologic malignancies unde…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Laser vs Ozone Therapy for Oral Mucositis in Cancer Patients [NA]
A completed clinical trial compared laser therapy to ozone therapy for oral mucositis in cancer patients. The brief indicates the study is f…
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CLINICAL_TRIALS trial_result · 2025-10-28Clinical Trial Update: TRial to EvaluAte Tranexamic Acid Therapy in Thrombocytopenia [Phase 3]
Phase 3 trial evaluating tranexamic acid therapy for bleeding in thrombocytopenia has completed and posted results.