Hematologic Malignancies
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies [EARLY_Phase 1]
APG-2575 is being studied in a Phase 1 trial to evaluate its safety, tolerability, and PK/PD in patients with hematologic malignancies.
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: Drug Response Profiling (DRP) Registry Zurich for Hematological Malignancies
The Drug Response Profiling (DRP) Registry in Zurich for hematologic malignancies is currently recruiting participants to profile drug respo…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Haplo-PBSC+Cord vs Haplo-PBSC+BM for Hematological Malignancies Undergoing Allo-HSCT [Phase 3]
A Phase 3 clinical trial comparing haploidentical peripheral blood stem cell plus cord blood versus haploidentical peripheral blood stem cel…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: Positive Psychology Intervention In HSCT [NA]
Completed clinical trial evaluating a positive psychology intervention in hematopoietic stem cell transplant patients; results were posted o…
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: An Epidemiological Study to Investigate the Characteristics of RSV Infection in Adult Hematopoietic Cell Transplant Recipients or Hematological Malignancies Patients in Tianjin HI (Hematology Institute)
This document describes an epidemiological study aimed at characterizing RSV infection in adults who have undergone hematopoietic cell trans…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy [Phase 1, Phase 2]
This document reports completion and results posting for a Phase 1/2 study evaluating leflunomide as a treatment for severe COVID-19 in pati…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Pharmacokinetics of Liposomal Amphotericin B in Critically Ill vs. Non-critically Ill Hematological Patients: Exploration of Covariates
A clinical trial update investigating the pharmacokinetics of liposomal amphotericin B in critically ill versus non-critically ill hematolog…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Proof-of-Concept Trial of a Positive Psychology Intervention for Caregivers of Patients Undergoing HSCT [NA]
A completed proof-of-concept trial tested a positive psychology intervention for caregivers of patients undergoing hematopoietic stem cell t…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: Metagenomic Sequencing for the Identification of Pathogens in Febrile Neutropenic Patients [NA]
Clinical trial investigating metagenomic sequencing to identify pathogens in febrile neutropenic, immunocompromised patients with hematologi…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E) [Phase 2]
Phase 2 MATCH subprotocol evaluating AZD9291 (osimertinib) as a targeted treatment for cancers with EGFR genetic changes; the trial is curre…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients [NA]
A clinical trial comparing ceftolozane/tazobactam with piperacillin/tazobactam for bacteremia in hematologic malignancy patients with neutro…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: A Trial of PF-07901800 (TTI-621) for Patients With Hematologic Malignancies and Selected Solid Tumors [Phase 1]
Pfizer's Phase 1 trial of PF-07901800 (TTI-621) in patients with hematologic malignancies and selected solid tumors was terminated, with res…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Outcomes of Critically Ill Patients With Hematologic Malignancies
Clinical trial update summarizing the outcomes of critically ill patients with hematologic malignancies; the study status is completed.
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Durvalumab and Tremelimumab for Pediatric Malignancies [Phase 1, Phase 2]
Phase 1/2 trial evaluating durvalumab and tremelimumab in pediatric malignancies has results posted; the study is currently active but not r…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN [Phase 2]
Phase II, single-center randomized open-label trial evaluating the impact of serial procalcitonin measurements in patients with hematologic …
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CLINICAL_TRIALS trial_result · 2024-01-24Clinical Trial Update: Clinical Trial for Non-inferiority and Safety of Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in Patients With Hematologic Malignancies Who Require Prophylactic Hepatitis B Antiviral Treatment [Phase 4]
Phase 4 trial evaluating non-inferiority and safety of Tenofovir Alafenamide vs Tenofovir Disoproxil Fumarate in patients with hematologic m…
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FDA approval · 2023-07-27FDA Approved: KEPIVANCE — Supplemental Application (Swedish Orphan Biovitrum AB (publ))
The FDA approved a supplemental application for Kepivance (palifermin) from Swedish Orphan Biovitrum AB (publ). This action updates the prod…
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CLINICAL_TRIALS trial_result · 2023-07-17Clinical Trial Update: Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant [Phase 3]
Phase 3 trial evaluating whether Lactobacillus plantarum can prevent acute graft-versus-host disease in children undergoing donor stem cell …
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CLINICAL_TRIALS trial_result · 2023-06-12Clinical Trial Update: An Open-Label, Dose-Escalation/Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced Malignancies [Phase 1, Phase 2]
Open-label Phase 1/2 dose-escalation/expansion study of INCB059872 in advanced malignancies, assessing safety and preliminary activity; the …
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 trial of ProTmune for allogeneic hematopoietic cell transplantation in adults with hematologic malignancies completed; results pos…
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CLINICAL_TRIALS trial_result · 2021-08-31Clinical Trial Update: A Study of CN202 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors or Hematologic Malignancies [Phase 1, Phase 2]
Clinical trial update for CN202 in adults with locally advanced or metastatic solid tumors or hematologic malignancies (Phase 1/2).
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CLINICAL_TRIALS trial_result · 2021-07-16Clinical Trial Update: Efficacy of Mirasol-treated Apheresis Platelets in Patients With Hypoproliferative Thrombocytopenia [NA]
Clinical trial update on the efficacy of Mirasol-treated apheresis platelets in patients with hypoproliferative thrombocytopenia; study term…
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CLINICAL_TRIALS trial_result · 2021-05-19Clinical Trial Update: A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and Clinical Activity of GSK525762 in Subjects With Relapsed, Refractory Hematologic Malignancies [Phase 2]
This clinical trial update reports results from a Phase 2 dose-escalation study evaluating safety, PK/PD, and clinical activity of the gamma…
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CLINICAL_TRIALS trial_result · 2021-02-16Clinical Trial Update: Cyclophosphamide for Hematopoietic Stem Cell Mobilization in Patients With a Hematologic Malignancy [Phase 2]
Phase 2 trial investigating cyclophosphamide for mobilization of hematopoietic stem cells in patients with hematologic malignancies has comp…
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CLINICAL_TRIALS trial_result · 2021-01-07Clinical Trial Update: Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant [Phase 3]
Phase 3 trial comparing caspofungin acetate, fluconazole, and voriconazole for preventing fungal infections in patients after donor hematopo…