Hematologic Malignancies
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-11-23Clinical Trial Update: Chemotherapy Followed by Allogeneic Stem Cell Transplantation for Hematologic Malignancies [NA]
Clinical trial update on chemotherapy followed by allogeneic stem cell transplantation for hematologic malignancies; study completed with re…
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CLINICAL_TRIALS trial_result · 2020-10-20Clinical Trial Update: Ruxolitinib and Decitabine for High Risk Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 trial evaluating ruxolitinib and decitabine for high risk hematological malignancies in the peripheral blood stem cell transplanta…
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CLINICAL_TRIALS trial_result · 2020-02-25Clinical Trial Update: Partially HLA Mismatched (Haploidentical) Allogeneic Bone Marrow Transplantation [Phase 2]
A Phase 2 clinical trial of partially HLA-mismatched haploidentical allogeneic bone marrow transplantation for hematologic malignancies was …
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
A combined Phase 1/Phase 2 trial evaluating mycophenolate mofetil with cyclosporine to reduce graft-versus-host disease in patients undergoi…
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide [Phase 2]
Phase 2 clinical trial update on mismatched transplantation using high-dose post-transplant cyclophosphamide completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-01-06Clinical Trial Update: Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating carfilzomib to prevent relapse and graft-versus-host disease in allogeneic stem cell transplant for hema…
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FDA approval · 2019-12-18FDA Approved: KEPIVANCE — Supplemental Application (Swedish Orphan Biovitrum AB (publ))
FDA approved a supplemental application for KEPIVANCE (palifermin) filed by Swedish Orphan Biovitrum AB (publ), expanding its label for the …
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: Umbilical Cord Transplantation for the Elderly Population [Phase 2]
Phase 2 clinical trial update on umbilical cord transplantation for elderly patients with hematologic malignancies.
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CLINICAL_TRIALS trial_result · 2019-08-08Clinical Trial Update: Dose Escalation Study of MLN0128 in Combination With Paclitaxel, With/Without Trastuzumab, in Subjects With Advanced Solid Malignancies [Phase 1]
Phase 1 dose-escalation study of MLN0128 (sapanisertib) in combination with paclitaxel, with/without trastuzumab, in subjects with advanced …
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: BGJ398 for Patients With Tumors With FGFR Genetic Alterations [Phase 2]
Phase 2 trial update of BGJ398 (infigratinib) for tumors with FGFR genetic alterations; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-06-14Clinical Trial Update: An Open-Label, Dose-Escalation Study of INCB054329 in Patients With Advanced Malignancies [Phase 1, Phase 2]
Open-label dose-escalation trial of INCB054329 in patients with advanced solid tumors and hematologic malignancies has terminated; results p…
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CLINICAL_TRIALS trial_result · 2019-04-18Clinical Trial Update: Myeloablative Haploidentical BMT With Post-transplant Cyclophosphamide for Pediatric Patients With Hematologic Malignancies [Phase 2]
A Phase 2 trial evaluating myeloablative haploidentical bone marrow transplantation with post-transplant cyclophosphamide in pediatric patie…
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CLINICAL_TRIALS research · 2019-02-18Clinical Trial Update: Influence of a Combined Pharmacogenetic Score on Through Plasma Voriconazole Concentrations in Haematological Patients
A completed clinical trial evaluating whether a combined pharmacogenetic score influences trough voriconazole concentrations in patients wit…
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies [Phase 2, Phase 3]
This clinical trial update describes ongoing Phase 2/Phase 3 evaluation of post-transplant cyclophosphamide to prevent graft-versus-host dis…
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: Retrospective Descriptive Study of Platelet Transfusion in Patients With Palliative Hematologic Malignancies at the University Hospital of Besançon
A completed retrospective descriptive study from Besançon University Hospital evaluated platelet transfusion in patients with palliative hem…
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CLINICAL_TRIALS research · 2019-01-23Clinical Trial Update: Onco-coaching of Sport-inspired for the Social, Professional and Psychological Restoring of the Patients in Cancer Remission After Allogeneic Transplantation of Hematopoietic Stem Cells [NA]
A clinical trial update for NCT03272789 evaluating sport-inspired onco-coaching to aid social, professional, and psychological recovery in p…
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CLINICAL_TRIALS trial_result · 2018-12-13Clinical Trial Update: Prophylactic Donor Lymphocyte Infusion After Allo-PBSCT for Patients With Very High-risk Hematologic Malignancies [Phase 2]
Phase 2 clinical trial update on prophylactic donor lymphocyte infusion after allogeneic peripheral blood stem cell transplantation for very…
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CLINICAL_TRIALS trial_result · 2018-10-10Clinical Trial Update: A Phase 1 Trial of a Single ProHema® CB Product for Pediatric Patients With Hematologic Malignancies [Phase 1]
Phase 1 trial update of a single ProHema CB product for pediatric hematologic malignancies; study terminated with results posted.
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CLINICAL_TRIALS withdrawal · 2018-07-06Clinical Trial Update: Transplantation of Hematopoietic Progenitors From Haploidentical Donor With Selective in Vitro Depletion Allo-reactive Lymphocytes in Patient With High Risk Hematological Malignancies [Phase 1]
A Phase 1 trial evaluating haploidentical hematopoietic progenitor transplantation with selective in vitro depletion of allo-reactive lympho…
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Study to Evaluate Safety, Tolerability, Maximum Tolerated Dose (MTD), Efficacy, and Pharmacokinetics (PKs) of CPI-613 Given Twice Weekly for Three Consecutive Weeks in Patients With Advanced Hematologic Malignancies [Phase 1]
Phase 1 study evaluating CPI-613 (devimistat) given twice weekly for three consecutive weeks in patients with advanced hematologic malignanc…
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CLINICAL_TRIALS trial_result · 2018-06-07Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation for High-Risk Hematologic Malignancies Using One Haploidentical Donor [Phase 2]
This Phase 2 trial evaluated allogeneic hematopoietic stem cell transplantation from a single haploidentical donor for high-risk hematologic…
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Safety Study of AP24534 to Treat Chronic Myelogenous Leukemia (CML) and Other Hematological Malignancies [Phase 1]
This update describes safety data from a Phase 1 study of AP24534 (ponatinib) in patients with chronic myeloid leukemia and other hematologi…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation Using a Non-myeloablative Preparative Regimen of Total Lymphoid Irradiation and Anti-thymocyte Globulin for Older Patients With Relapsed Lymphoid Malignancies [Phase 2]
Phase 2 trial of a non-myeloablative preparative regimen using total lymphoid irradiation and anti-thymocyte globulin for older patients wit…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: Assessing Physical Fitness in Cancer Patients With Cardiopulmonary Exercise Testing and Wearable Data Generation
A completed clinical trial update assessing physical fitness in cancer patients using cardiopulmonary exercise testing and wearable data gen…
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CLINICAL_TRIALS trial_result · 2018-03-16Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies [Phase 2]
Phase 2 study evaluating donor stem cell transplantation for high-risk hematologic malignancies has completed and posted results in 2018.