Hematologic Malignancies
📧 Sign up to get email alerts when something new happens for Hematologic Malignancies.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2013-10-22Clinical Trial Update: A Phase I, Dose-escalation Study of AS703569 Given Orally to Subjects With Haematological Malignancies [Phase 1]
A Phase 1 dose-escalation trial of AS703569 in hematologic malignancies was terminated.
-
CLINICAL_TRIALS trial_result · 2013-10-08Clinical Trial Update: Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies. [Phase 1]
A completed Phase 1 trial evaluating the safety and preliminary efficacy of Fate Therapeutics' ProHema modulated umbilical cord blood units …
-
CLINICAL_TRIALS research · 2013-09-17Clinical Trial Update: Screening to Predict Weight Loss in Patients With Cancer [NA]
Clinical trial update on screening to predict weight loss in cancer patients; the current status is unknown.
-
CLINICAL_TRIALS trial_result · 2013-07-25Clinical Trial Update: Bortezomib Plus Tacrolimus and Methotrexate to Prevent Graft Versus Host Disease (GVHD) After Mismatched Allogeneic Non-Myeloablative Blood Stem Cell Transplantation [Phase 1, Phase 2]
Results from a Phase 1/2 study evaluating the combination of bortezomib with tacrolimus and methotrexate to prevent graft-versus-host diseas…
-
CLINICAL_TRIALS trial_result · 2013-07-01Clinical Trial Update: Pegfilgrastim Versus Filgrastim After High-dose Chemotherapy [Phase 2]
A Phase 2 trial comparing pegfilgrastim versus filgrastim for neutrophil recovery after high-dose chemotherapy has completed.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: Dose-ranging Study of a Single Administration of T-cell Add-back Depleted of Host Alloreactive Cells in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor [Phase 1, Phase 2]
Completed Phase 1/2 dose-ranging trial evaluating a T-cell add-back product depleted of host alloreactive cells in patients receiving haploi…
-
FDA label_change · 2013-05-30FDA Approved: KEPIVANCE — Supplemental Application (Swedish Orphan Biovitrum AB (publ))
FDA approved a supplemental application for Kepivance (palifermin) to update the labeling related to mucositis prevention in patients with h…
-
CLINICAL_TRIALS trial_result · 2013-05-10Clinical Trial Update: Infection Rates of Myeloablative Allo SCT Recipients Receiving Neutropenic Diets Versus Non-Neutropenic Diets [NA]
Completed clinical trial comparing neutropenic diets versus non-neutropenic diets in patients undergoing myeloablative allogeneic stem cell …
-
CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Recombinant Human Keratinocyte Growth Factor to Reduce Oral Mucositis in Hematologic Malignancy Patients Undergoing Peripheral Blood Stem Cell Transplantation After Radiation and High-dose Chemotherapy [Phase 3]
Phase 3 trial evaluating recombinant human keratinocyte growth factor (Palifermin) to reduce oral mucositis in patients with hematologic mal…
-
CLINICAL_TRIALS trial_result · 2013-04-24Clinical Trial Update: Extracorporal Photopheresis Pilot Study [Phase 1, Phase 2]
This clinical trial update concerns a pilot extracorporeal photopheresis study conducted in Phase 1/Phase 2 for hematologic malignancies. Th…
-
CLINICAL_TRIALS research · 2013-04-01Clinical Trial Update: Cologne Cohort of Neutropenic Patients (CoCoNut)
The Cologne cohort of neutropenic patients (CoCoNut) is currently recruiting, with no trial results or drug details reported in this update.
-
CLINICAL_TRIALS trial_result · 2013-01-14Clinical Trial Update: Suicide Gene Therapy for Donor Lymphocytes Infusion After Allogeneic Hematopoietic Stem Cell Transplantation [Phase 1, Phase 2]
Phase 1/2 trial of suicide gene–modified donor lymphocyte infusion after allogeneic hematopoietic stem cell transplantation has completed.
-
CLINICAL_TRIALS trial_result · 2012-08-20Clinical Trial Update: The Utility of Multiplex PCR for Detection of DNA in Neutropenic Patients With Hematological Malignancies
A completed clinical trial evaluating multiplex PCR for detecting DNA in neutropenic patients with hematologic malignancies.
-
CLINICAL_TRIALS trial_result · 2012-06-06Clinical Trial Update: Intra-bone Cord Blood Transplantation in Patients With Haematological Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating intra-bone cord blood transplantation in patients with high-risk or advanced hematologic malignancies; c…
-
CLINICAL_TRIALS trial_result · 2012-05-28Clinical Trial Update: Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignancies [Phase 2]
Phase 2 clinical trial evaluating stem cell transplantation with T-cell add-back for hematologic malignancies and bone marrow transplant rej…
-
CLINICAL_TRIALS research · 2012-05-01Clinical Trial Update: A Study to Determine the Absorption, Distribution, Metabolism, and Excretion of LBH589 [Phase 1]
A Phase 1 study to determine the absorption, distribution, metabolism, and excretion of LBH589 (panobinostat) in cancer patients with advanc…
-
CLINICAL_TRIALS trial_result · 2012-04-23Clinical Trial Update: A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine [Phase 1]
Phase I dose-escalation study of oral SB939 alone or with azacitidine has completed, assessing safety/dosing in solid tumors and hematologic…
-
CLINICAL_TRIALS trial_result · 2012-04-10Clinical Trial Update: A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders
This is a single-arm safety study evaluating transplantation using umbilical cord blood and placental-derived stem cells from partially matc…
-
CLINICAL_TRIALS trial_result · 2012-04-04Clinical Trial Update: Repeat Dose Safety Study for Compound to Treat Hematologic Cancer [Phase 1, Phase 2]
Completed Phase 1/2 safety study evaluating a compound for hematologic malignancies, focusing on repeat-dose safety.
-
CLINICAL_TRIALS trial_result · 2012-03-29Clinical Trial Update: Donor Dendritic Cells And Donor Lymphocytes in Patients With Relapsed Hematologic Malignancies After Allogeneic Transplant [Phase 1]
Phase 1 study assessing safety of donor dendritic cells and donor lymphocyte infusions in patients with relapsed hematologic malignancies af…
-
CLINICAL_TRIALS trial_result · 2012-03-08Clinical Trial Update: Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation [Phase 2]
This is a Phase 2 clinical trial update evaluating tacrolimus, sirolimus, and methotrexate as prophylaxis for graft-versus-host disease afte…
-
CLINICAL_TRIALS trial_result · 2012-02-28Clinical Trial Update: Phase I/II Trial of Fludarabine Plus Busulfan and Allogeneic Progenitor Cell Support [Phase 1, Phase 2]
This clinical trial update reports completion and posting of results for a Phase I/II study of fludarabine plus busulfan with allogeneic pro…
-
CLINICAL_TRIALS research · 2012-02-15Clinical Trial Update: Neutrophil Extracellular Traps (NETs) Formation Following Chemotherapy and Their Role in Antitumor Activity
A clinical trial update examining how neutrophil extracellular traps formed after chemotherapy may contribute to antitumor activity in pedia…
-
CLINICAL_TRIALS trial_result · 2012-01-26Clinical Trial Update: Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Related Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial evaluating sirolimus plus tacrolimus for graft-versus-host disease prophylaxis after related stem cell transplantat…
-
CLINICAL_TRIALS research · 2012-01-24Clinical Trial Update: IUdR/BUdR Cell Cycle Labelling [NA]
The study by MD Anderson Cancer Center evaluating IUdR and BUdR cell cycle labeling in hematologic malignancies has completed.