Hematologic Malignancies
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Open-Label Study Designed to Evaluate the Safety and Preliminary Efficacy of ApoCell for the Prevention of Acute GvHD [Phase 1, Phase 2]
An open-label Phase 1/2 study is evaluating ApoCell for the prevention of acute graft-versus-host disease. The update notes safety and preli…
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CLINICAL_TRIALS withdrawal · 2015-06-08Clinical Trial Update: CD56+CD3- NK Cells Following Allogeneic Stem Cell Transplantation [Phase 1]
Phase 1 trial evaluating CD56+CD3- natural killer cells following allogeneic stem cell transplantation in hematologic malignancies has been …
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Phase I Study of mPEG-R-Crisantaspase Given IV [Phase 1]
Phase I intravenous study of mPEG-R-Crisantaspase for hematologic malignancies, sponsored by Jazz Pharmaceuticals, has completed.
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CLINICAL_TRIALS withdrawal · 2015-04-17Clinical Trial Update: Study to Investigate AKT Inhibitor GSK690693 in Subjects With Relapsed or Refractory Hematologic Malignancies [Phase 1]
A Phase 1 trial evaluating the AKT inhibitor GSK690693 in relapsed or refractory hematologic malignancies has been withdrawn.
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FDA label_change · 2015-03-13FDA Approved: KEPIVANCE — Supplemental Application (Swedish Orphan Biovitrum AB (publ))
FDA approved a supplemental labeling change for Kepivance (palifermin) submitted by Swedish Orphan Biovitrum AB (publ).
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CLINICAL_TRIALS research · 2015-03-11Clinical Trial Update: Phase II Study of Myeloablative Double Unit Umbilical Cord Blood Transplantation in Adult Patients [Phase 2]
Phase II clinical trial update evaluating myeloablative double unit umbilical cord blood transplantation in adults with hematologic malignan…
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CLINICAL_TRIALS trial_result · 2015-03-11Clinical Trial Update: A Randomized Multicenter Study to Compare Two Types of Transplant in Adult Patients With Hematologic Malignancies
A randomized multicenter clinical trial compares two transplant approaches in adult patients with hematologic malignancies. The status of th…
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CLINICAL_TRIALS trial_result · 2015-01-30Clinical Trial Update: An Open-Label Study to Investigate the Pharmacokinetics of Omacetaxine Mepesuccinate [Phase 1]
Open-label Phase 1 pharmacokinetics study of omacetaxine mepesuccinate; the trial completed, investigating PK in hematologic malignancies an…
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CLINICAL_TRIALS trial_result · 2015-01-13Clinical Trial Update: Transplantation of Ex-vivo Expanded Cord Blood Stems Cells [Phase 2]
Phase 2 trial evaluating transplantation of ex-vivo expanded cord blood stem cells for malignant hematologic diseases has completed.
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CLINICAL_TRIALS withdrawal · 2014-12-23Clinical Trial Update: Reiki as a Complementary Therapy: A Pilot Study [NA]
A pilot trial evaluating Reiki as a complementary therapy for hematologic malignancies has been withdrawn.
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CLINICAL_TRIALS research · 2014-12-08Clinical Trial Update: Efficacy Study of Ramosetron in the Setting of Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating the efficacy of Ramosetron in the setting of hematopoietic stem cell transplantation for hematologic malignancies. …
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CLINICAL_TRIALS withdrawal · 2014-09-19Clinical Trial Update: In-Vitro Studies in Depletion of Haplotype Mismatched Alloreactive T Cells
This withdrawal notice concerns an in vitro study on depletion of haplotype-mismatched alloreactive T cells in the hematologic malignancies …
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CLINICAL_TRIALS trial_result · 2014-09-18Clinical Trial Update: A Phase I Trial of Myeloablative Conditioning w/ Clofarabine and HD Busulfan for Pts w/ Refractory Heme Malignancies Undergoing Allo PBSCT [Phase 1]
A Phase I study evaluating conditioning with clofarabine and high-dose busulfan before allogeneic peripheral blood stem cell transplantation…
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation [Phase 2]
Phase 2 trial evaluating palifermin to reduce acute graft-versus-host disease in patients with hematologic malignancies undergoing allogenei…
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CLINICAL_TRIALS trial_result · 2014-08-19Clinical Trial Update: Granulocyte Colony Stimulating Factor (G-CSF) for Bone Marrow Transplant (BMT) [NA]
A completed clinical trial evaluated granulocyte colony-stimulating factor (filgrastim) in the bone marrow transplant setting, with results …
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CLINICAL_TRIALS trial_result · 2014-06-05Clinical Trial Update: Phase II Trial of Pentostatin and Targeted Busulfan [Phase 2]
Phase II trial evaluating pentostatin with targeted busulfan in hematologic malignancies has completed and posted results.
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CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Infusion of Donor Lymphocytes Transduced With the Suicide Gene HSV TK in Patients With Haematological Malignancies [Phase 1, Phase 2]
Phase 1/2 trial update on HSV-TK gene-transduced donor lymphocytes for hematologic malignancies; the study status is completed.
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CLINICAL_TRIALS trial_result · 2014-05-15Clinical Trial Update: Observational Study Investigating the Response Rate of Itraconazole Injection in Treating Immunocompromised Patients
A completed observational study by Janssen Korea evaluated the response rate of itraconazole injection in immunocompromised patients with he…
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CLINICAL_TRIALS trial_result · 2014-04-11Clinical Trial Update: Vorinostat to Prevent Graft Versus Host Disease Following Reduced Intensity, Related Donor Stem Cell Transplant [Phase 1, Phase 2]
This clinical trial update summarizes completed Phase 1/2 results evaluating vorinostat to prevent graft-versus-host disease after reduced-i…
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CLINICAL_TRIALS trial_result · 2014-03-10Clinical Trial Update: Adult Double Cord Blood Transplant Study [Phase 2]
Phase 2 clinical trial update for an adult double cord blood transplant study evaluating cord blood stem cell transplantation in hematologic…
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: Conditioning Treatment With Umbilical Cord Blood Transplant for Hematologic Malignancies [Phase 2]
A Phase 2 trial evaluating conditioning with an Umbilical Cord Blood Transplant for hematologic malignancies has been terminated.
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CLINICAL_TRIALS trial_result · 2013-12-24Clinical Trial Update: Unrelated Cord Blood Transplant Plus a Haplo-Identical (Half-Matched), T-Cell Depleted Stem Transplant From a Related Donor for Subjects With High Risk Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating an unrelated cord blood transplant plus a haplo-identical, T-cell depleted stem cell transplant from a r…
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CLINICAL_TRIALS research · 2013-12-11Clinical Trial Update: Study of Non-Myeloablative Haplo-identical Haematopoietic Stem Cell Transplantation in Patients With Haematological Malignancies or Acquired Aplastic Anaemia
This document provides an update on a clinical trial evaluating non-myeloablative haplo-identical hematopoietic stem cell transplantation in…
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CLINICAL_TRIALS trial_result · 2013-12-10Clinical Trial Update: Research Study to Determine if an Experimental Agent, LLME Can Decrease the Incidence and Severity of Graft-Versus-Host-Disease (GVHD) Following Blood (Hematopoietic) Stem Cell Transplantation [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated the experimental agent LLME for reducing the incidence and severity of graft-versus-host disease after…
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: Mindfulness Meditation in Bone Marrow Transplantation [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial from Emory University evaluating mindfulness meditation for patients undergoing bone marrow transplanta…