Heart Failure
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CLINICAL_TRIALS trial_result · 2019-06-03Clinical Trial Update: Internet Cognitive Behavioural Therapy to Patients With Heart Failure and Depression [NA]
Updates on a completed clinical trial evaluating Internet-based cognitive behavioral therapy for patients with heart failure and depressive …
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CLINICAL_TRIALS trial_result · 2019-05-28Clinical Trial Update: Aquaresis Utility for Hyponatremic Acute Heart Failure Study [Phase 4]
A Phase 4 clinical trial update for Aquaresis in hyponatremic acute heart failure has completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-05-28Clinical Trial Update: Clinical Evaluation of LEft VEntricular Auto Threshold Algorithm (LEVEA) [NA]
Clinical trial update for LEft VEntricular Auto Threshold Algorithm (LEVEA) evaluating its use in heart failure has completed with results p…
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FDA approval · 2019-05-24FDA Approved: DOBUTAMINE IN DEXTROSE — Supplemental Application (Hospira, Inc.)
FDA approved a supplemental application for Dobutamine in Dextrose from Hospira, Inc.
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CLINICAL_TRIALS trial_result · 2019-05-23Clinical Trial Update: Effect of Ivabradine in Stage D HF/Cardiogenic Shock Patients on Dobutamine [Phase 4]
Phase 4 clinical trial update assessing the effect of ivabradine in patients with Stage D heart failure and cardiogenic shock on dobutamine.
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device [Phase 3]
A Phase 3 international trial evaluating whether the AdreView heart function scan can identify heart failure patients who benefit from impla…
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Evaluating Myocardial Injury for Defibrillation Threshold Testing Methods for ICD Implantation [NA]
A completed clinical trial evaluating myocardial injury associated with defibrillation threshold testing methods for ICD implantation.
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CLINICAL_TRIALS trial_result · 2019-05-20Clinical Trial Update: A Dose Ranging Phase IIa Study of 6 Hour Intravenous Dosages of CXL-1427 in Patients Hospitalized With Heart Failure [Phase 2]
A Phase 2a dose-ranging trial evaluating 6-hour IV doses of CXL-1427 in hospitalized heart failure patients has completed, with results post…
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FDA approval · 2019-05-19FDA Approved: BENAZEPRIL HYDROCHLORIDE — Supplemental Application (Amneal Pharmaceuticals of New York LLC)
The FDA approved a supplemental application for benazepril hydrochloride submitted by Amneal Pharmaceuticals of New York LLC, indicating an …
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CLINICAL_TRIALS research · 2019-05-14Clinical Trial Update: The Role of Sleep Apnea in the Acute Exacerbation of Heart Failure [NA]
Clinical trial update examining the role of sleep apnea in acute exacerbation of heart failure; status completed with results posted.
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FDA approval · 2019-05-13FDA Approved: CORLANOR — Supplemental Application (Amgen Inc)
FDA approved Amgen's supplemental application for CORLANOR (ivabradine), updating the product's labeling.
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure [Phase 3]
Phase 3 trial evaluating rivaroxaban to reduce death, myocardial infarction, or stroke in heart failure patients with coronary artery diseas…
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CLINICAL_TRIALS trial_result · 2019-05-09Clinical Trial Update: Effect of Servo-Ventilation on CO2 Regulation and Heart Rate Variability [Phase 4]
Phase 4 clinical trial evaluating how servo-ventilation affects CO2 regulation and heart rate variability in patients with sleep apnea (mixe…
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FDA approval · 2019-05-03FDA Approved: FUROSEMIDE — Original Application (Eugia US LLC)
FDA approved an original ANDA for FUROSEMIDE by Eugia US LLC, confirming a generic version of the diuretic. This is a routine generic drug a…
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CLINICAL_TRIALS trial_result · 2019-05-02Clinical Trial Update: Longitudinal Surveillance Registry (LSR) of ACUITY Spiral
A longitudinal surveillance registry (LSR) for ACUITY Spiral in heart failure patients was terminated; results were posted in 2019.
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FDA approval · 2019-04-24FDA Approved: BUMETANIDE — Supplemental Application (Upsher-Smith Laboratories, LLC)
The FDA approved a supplemental application for Bumetanide from Upsher-Smith Laboratories, LLC.
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FDA approval · 2019-04-22FDA Approved: CORLANOR — Original Application (Amgen Inc)
The FDA approved CORLANOR (ivabradine) under Amgen's original NDA, marking the initial approval of the product for its indicated use.
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CLINICAL_TRIALS trial_result · 2019-04-17Clinical Trial Update: Bone Marrow Cell Transplantation to Improve Heart Function in Individuals With End-Stage Heart Failure [Phase 2]
Phase 2 trial investigating bone marrow cell transplantation to improve heart function in individuals with end-stage heart failure; study te…
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CLINICAL_TRIALS research · 2019-04-17Clinical Trial Update: Exercise Training Following Cardiac Resynchronization Therapy in Patients With Chronic Heart Failure [NA]
Clinical trial update on exercise training following cardiac resynchronization therapy in patients with chronic heart failure; study complet…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Spot Urinary Analysis to Assess Loop Diuretic Efficiency in Stable Heart Failure [NA]
Clinical trial update for a study evaluating spot urinary analysis to assess loop diuretic efficiency in stable heart failure; the trial is …
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CLINICAL_TRIALS trial_result · 2019-04-12Clinical Trial Update: Pressure Variability Study [NA]
Completed clinical trial on pressure variability in heart failure; results posted.
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CLINICAL_TRIALS trial_result · 2019-04-10Clinical Trial Update: Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD [Phase 4]
Phase 4 trial comparing ablation versus amiodarone for atrial fibrillation in patients with heart failure and an ICD has completed.
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CLINICAL_TRIALS trial_result · 2019-04-10Clinical Trial Update: Evaluation of Cardiac Compass With OptiVol in the Early Detection of Decompensation Events for Heart Failure [NA]
A terminated clinical trial evaluating Cardiac Compass with OptiVol for early detection of decompensation events in congestive heart failure…
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CLINICAL_TRIALS trial_result · 2019-04-08Clinical Trial Update: Care Guides in the Primary Care Office (Phase II) [Phase 2]
Phase II clinical trial evaluating care guides in a primary care office setting for diabetes and hypertension, with additional mention of co…
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CLINICAL_TRIALS trial_result · 2019-03-29Clinical Trial Update: Acupuncture on Cardiac and Autonomic Function in Human Heart Failure [NA]
A completed clinical trial investigated the effects of acupuncture on cardiac and autonomic function in individuals with chronic heart failu…