Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-08-02Clinical Trial Update: Premature Fatigue in Veterans With Heart Failure: Neuronal Influences [EARLY_Phase 1]
Early-phase trial update investigating neuronal influences on premature fatigue in veterans with heart failure; study completed with results…
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CLINICAL_TRIALS trial_result · 2019-08-01Clinical Trial Update: Systematic Withdrawal of Neurohumoral Blocker Therapy in Optimally Responding CRT Patients [Phase 4]
Phase 4 trial updating systematic withdrawal of neurohumoral blocker therapy in optimally responding CRT patients with heart failure has com…
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CLINICAL_TRIALS trial_result · 2019-07-30Clinical Trial Update: Changes in Myocardial Iron After Iron Administration [Phase 4]
Phase 4 trial update examining changes in myocardial iron after iron administration in patients with heart failure and iron deficiency.
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Clinical Trial of the Edwards Aortic Bioprosthesis, Model 11000 [NA]
Clinical trial of the Edwards Aortic Bioprosthesis, Model 11000 has completed; results were posted in 2019.
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FDA approval · 2019-07-25FDA Approved: SPIRONOLACTONE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
The FDA approved a supplemental application for spironolactone submitted by Sun Pharmaceutical Industries, Inc., indicating an update to the…
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: Mineralocorticoid Receptor Antagonists (MRA) in Heart Failure (HF) and Loop Diuretic Resistance [Phase 2, Phase 3]
A completed Phase 2/3 trial update on mineralocorticoid receptor antagonists for heart failure and loop diuretic resistance.
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CLINICAL_TRIALS trial_result · 2019-07-22Clinical Trial Update: The Study of Qishenyiqi Drop Pills in Improving the Prognosis of Heart Failure Patients [Phase 4]
Phase 4 clinical trial update on Qishenyiqi Drop Pills for improving prognosis in heart failure patients.
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CLINICAL_TRIALS trial_result · 2019-07-17Clinical Trial Update: Effect of Levosimendan or Placebo on Exercise in Advanced Chronic Heart Failure [Phase 4]
A Phase 4 clinical trial assessing the effect of levosimendan versus placebo on exercise capacity in advanced chronic heart failure.
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CLINICAL_TRIALS trial_result · 2019-07-12Clinical Trial Update: Ferric Carboximaltose on Intra-myocardial Iron Load in Patients With Heart Failure [Phase 4]
Phase 4 trial evaluating ferric carboxymaltose effect on intra-myocardial iron load in patients with heart failure with a focus on systolic …
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FDA approval · 2019-07-12FDA Approved: ETHACRYNIC ACID — Original Application (TRUPHARMA LLC)
FDA approves the original ANDA for Ethacrynic acid by Trupharma LLC, enabling its generic distribution as a loop diuretic. The approval cove…
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CLINICAL_TRIALS trial_result · 2019-07-11Clinical Trial Update: Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support [Phase 3]
A Phase 3 clinical trial evaluating prevention of hemorrhage after implantation of a mechanical circulatory support device has been terminat…
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CLINICAL_TRIALS trial_result · 2019-07-11Clinical Trial Update: Post- Approval Study on Patients Who Received a HeartWare HVAD® During IDE Trials
Post-approval study updating outcomes for patients who received the HeartWare HVAD during IDE trials; completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-07-10Clinical Trial Update: Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement [Phase 2]
Phase 2 clinical trial update on a noninvasive, subharmonic intra-cardiac pressure measurement method; study completed.
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CLINICAL_TRIALS trial_result · 2019-07-09Clinical Trial Update: The Effect of GHRH Therapy on Myocardial Structure and Function in Congestive Heart Failure [Phase 2]
Phase 2 trial update evaluating GHRH therapy on myocardial structure and function in congestive heart failure; results posted after completi…
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CLINICAL_TRIALS research · 2019-07-09Clinical Trial Update: Randomized Study of Coronary Revascularization Surgery With Injection of WJ-MSCs and Placement of an Epicardial Extracellular Matrix [Phase 1, Phase 2]
A randomized study evaluating coronary revascularization surgery with injections of Wharton's Jelly mesenchymal stem cells and epicardial ex…
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CLINICAL_TRIALS trial_result · 2019-07-08Clinical Trial Update: The Effects of Neprilysin on Glucagon-like Peptide-1 [Phase 4]
Phase 4 clinical trial update studying the effects of neprilysin on glucagon-like peptide-1 in diabetes and heart failure.
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: CARE-HF Long Term Follow-up
This update reports the long-term follow-up results of the CARE-HF trial evaluating cardiac resynchronization therapy in heart failure; resu…
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: Use of Oxygen in Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase 2 trial update evaluating the use of oxygen in heart failure with preserved ejection fraction (HFpEF) has completed.
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CLINICAL_TRIALS trial_result · 2019-06-25Clinical Trial Update: Pharmacokinetics & Safety of Serelaxin on Top of Standard of Care Therapy in Pediatric Patients With Acute Heart Failure [Phase 2]
Phase 2 trial assessing pharmacokinetics and safety of serelaxin added to standard of care in pediatric acute heart failure; the study was t…
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CLINICAL_TRIALS trial_result · 2019-06-21Clinical Trial Update: Multiple Dose Study in Heart Failure of BAY 1067197 [Phase 2]
Phase 2 multiple-dose study of BAY 1067197 in heart failure has completed.
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: ALternate Site Cardiac ReSYNChronization (ALSYNC) Study [NA]
Clinical trial update for the ALSYNC study related to cardiac resynchronization therapy in heart failure patients; results posted after comp…
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Effect of Aldosterone on Energy Starvation in Heart Failure [Phase 4]
Phase 4 trial update on the effects of aldosterone in energy metabolism among heart failure patients with nonischemic dilated cardiomyopathy…
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FDA approval · 2019-06-12FDA Approved: DIOVAN — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for DIOVAN (valsartan) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2019-06-11Clinical Trial Update: The Role of Sleep Disordered Breathing in Heart Failure Admissions [NA]
Trial update on the role of sleep-disordered breathing in heart failure admissions; study terminated with results posted in 2019.
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CLINICAL_TRIALS withdrawal · 2019-06-07Clinical Trial Update: AC6 Gene Transfer in Patients With Reduced Left Ventricular Ejection Fraction Heart Failure [Phase 3]
Phase 3 trial of AC6 gene transfer in patients with reduced left ventricular ejection fraction heart failure has been withdrawn.