Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2023-12-15Clinical Trial Update: Beneficial Effects of Vitamin D Combined With Oral Iron Supplementation in Patients With Chronic Heart Failure and Iron Deficiency [Phase 4]
Phase 4 trial investigating the beneficial effects of combining vitamin D with oral iron supplementation in chronic heart failure patients w…
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: Cardiovascular Effects of Preferred Home-based Exercise Training in Systolic Heart Failure [Phase 3]
A Phase 3 clinical trial update evaluating cardiovascular effects of preferred home-based exercise training in patients with systolic heart …
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: The Impact of Magnesium on Exercise Tolerance, Quality of Life and Clinical Outcomes in Chronic Heart Failure Patients [Phase 3]
Phase 3 trial exploring magnesium supplementation effects on exercise tolerance, quality of life, and outcomes in chronic heart failure pati…
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Group Medical Visits in Heart Failure [NA]
A completed clinical trial evaluating group medical visits for patients with heart failure; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Glutamate for Metabolic Intervention in Coronary Surgery II [Phase 3]
Phase 3 clinical trial update on glutamate-based metabolic intervention in coronary surgery completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Efficacy and Safety of corticoSTEROids Added to Standard Therapy in Patients With Acute Heart Failure (STERO-AHF) [Phase 2, Phase 3]
Clinical trial update on the efficacy and safety of adding corticoSTEROids to standard therapy for acute heart failure in a Phase 2/Phase 3 …
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Apogee, A HeartWare HVAD Destination Product Surveillance Registry (PSR) Platform
Clinical trial update for the Apogee HeartWare HVAD Destination Product Surveillance Registry platform; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-12-01Clinical Trial Update: Micronutrient Supplementation in Patients With Heart Failure [Phase 2, Phase 3]
A completed Phase 2/Phase 3 clinical trial assessing micronutrient supplementation in patients with heart failure has results posted.
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: Hemodynamic Effects of Chronic Ketosis. [Phase 2]
A Phase 2 clinical trial assessing the hemodynamic effects of chronic ketosis in patients with heart failure has been completed.
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: Metabolic Effects of Chronic Ketosis (KETO-CHF Metabolic) [Phase 2]
Phase 2 trial evaluating metabolic effects of chronic ketosis in heart failure has completed.
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FDA approval · 2023-11-29FDA Approved: IVABRADINE — Original Application (Zydus Pharmaceuticals USA Inc.)
The FDA approved an Original Application for IVABRADINE from Zydus Pharmaceuticals USA Inc., authorizing a generic IVABRADINE product.
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Adaptive CRT Effect on Electrical Dyssynchrony [NA]
This clinical trial update reports results from NCT02543281, evaluating adaptive cardiac resynchronization therapy (CRT) and its effect on e…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Treating Heart Failure With hiPSC-CMs [Phase 1, Phase 2]
A clinical trial update is reported for treating heart failure using hiPSC-derived cardiomyocytes, spanning Phase 1 and Phase 2, with an unk…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: SGLT2 Inhibitors in Patients With ADHF During Ventilator Weaning [Phase 3]
Phase 3 trial investigating SGLT2 inhibitors in patients with acute heart failure during ventilator weaning; currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-11-15Clinical Trial Update: STARBRITE: A Randomized Pilot Trial of BNP-Guided Therapy in Patients With Advanced Heart Failure [Phase 2]
A Phase 2 randomized pilot trial evaluating BNP-guided therapy in patients with advanced congestive heart failure has completed.
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Hypertonic Saline Therapy in Ambulatory Heart Failure Unit. [Phase 3]
A Phase 3 trial evaluating hypertonic saline therapy for heart failure has completed, reporting results from ambulatory care settings.
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CLINICAL_TRIALS trial_result · 2023-11-08Clinical Trial Update: Pharmacodynamic Study of Carvedilol Versus Metoprolol in Heart Failure [Phase 4]
Phase 4 pharmacodynamic study comparing carvedilol to metoprolol in heart failure has completed.
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FDA approval · 2023-11-01FDA Approved: CARVEDILOL — Supplemental Application (Glenmark Pharmaceuticals Inc., USA)
The FDA approved Glenmark's supplemental application for carvedilol, allowing continued marketing of the generic product.
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: PARTNER 3 Trial - Mitral Valve in Valve [NA]
Edwards Lifesciences provides an update on the PARTNER 3 trial evaluating mitral valve-in-valve procedures for mitral valve disease. Results…
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: A Multicenter Clinical Trial on DH001 Tablets in the Prevention of Doxorubicin-induced Cardiotoxicity in Cancer Patients [Phase 2]
Phase 2 multicenter trial evaluating DH001 tablets to prevent doxorubicin-induced cardiotoxicity in cancer patients; current status is unkno…
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FDA approval · 2023-10-18FDA Approved: ENTRESTO — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for ENTRESTO (sacubitril and valsartan) from Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: The VALIDATE Study of Valsartan for Patients With Early Stage Heart Failure [Phase 4]
Phase 4 clinical trial update for valsartan in early stage heart failure and hypertension.
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FDA approval · 2023-10-10FDA Approved: SPIRONOLACTONE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for spironolactone by Mylan Pharmaceuticals Inc., updating the approval for this generic diuretic. T…
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FDA approval · 2023-10-06FDA Approved: HYDRALAZINE HYDROCHLORIDE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
The FDA approved a supplemental application for Hydralazine Hydrochloride (generic) from Heritage Pharmaceuticals (d/b/a Avet Pharmaceutical…
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Effect of Passive Exercise on Systemic Endothelial Function in Elderly Patients With Chronic Heart Failure [Phase 4]
Phase 4 trial evaluating the effect of passive exercise on systemic endothelial function in elderly patients with chronic heart failure has …