Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2024-03-01FDA Approved: DEFINITY — Supplemental Application (Lantheus Medical Imaging, Inc.)
FDA approved a supplemental application for DEFINITY (perflutren) from Lantheus Medical Imaging, Inc., resulting in updated labeling and/or …
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Clinical Outcomes of Dapagliflozin in Acute Heart Failure With Reduced Ejection Fraction (CODA-HFrEF) [Phase 4]
Phase 4 trial update on dapagliflozin in acute heart failure with reduced ejection fraction assessing clinical outcomes.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Effect of Dual Bronchodilation With Umeclidinium/Vilanterol on Patients With COPD, Hyperinflation and Heart Failure [Phase 4]
Phase 4 trial evaluating dual bronchodilation with umeclidinium/vilanterol in COPD patients with hyperinflation and heart failure.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: COVID-19 Testing in Underserved and Vulnerable Populations [NA]
Clinical trial with terminated status related to COVID-19 testing in underserved populations; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-16Clinical Trial Update: Empagliflozin for New On-set Heart Failure Study Regardless of Ejection Fraction [Phase 3]
Phase 3 trial update for empagliflozin in acute heart failure regardless of ejection fraction is ongoing; current status unknown.
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CLINICAL_TRIALS trial_result · 2024-02-16Clinical Trial Update: Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure. [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating the acute hemodynamic and pulmonary congestion effects of furosemide in acute decompensated heart…
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: This Study Combines Data From 3 Other Studies Testing Empagliflozin in Patients With Diabetes or With Chronic Heart Failure. The Study Looks at the Numbers of Patients Who Had Lower Limb Amputations
A clinical trial update pooling data from three studies on empagliflozin in diabetes or chronic heart failure analyzes the incidence of lowe…
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Repurposing Empagliflozin and Dapagliflozin for Paediatric Heart Failure: Translational Approach and Dose Rationale [Phase 2]
Phase 2 clinical trial exploring repurposing empagliflozin and dapagliflozin for paediatric heart failure with a translational approach and …
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CLINICAL_TRIALS trial_result · 2024-02-06Clinical Trial Update: Stellate Ganglion Block as Novel Treatment for Heart Failure Patients [Phase 2, Phase 3]
A clinical trial update discusses Stellate Ganglion Block as a treatment for heart failure in Phase 2 and Phase 3, with unclear status.
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Survival Study of the Recombinant Human Neuregulin-1β in Subjects With Chronic Heart Failure. [Phase 3]
Phase 3 clinical trial update assessing survival with recombinant human neuregulin-1β in chronic heart failure; results status currently Unk…
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FDA approval · 2024-01-30FDA Approved: ISOSORBIDE DINITRATE AND HYDRALAZINE HYDROCHLORIDE — Supplemental Application (A2A Integrated Pharmaceuticals)
FDA approved a supplemental application for Isosorbide Dinitrate and Hydralazine Hydrochloride from A2A Integrated Pharmaceuticals.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Mechanism and Effects of Manipulating Chloride Homeostasis in Acute Heart Failure [EARLY_Phase 1]
Early-phase trial investigating manipulation of chloride homeostasis in acute heart failure; completed with posted results in 2024.
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CLINICAL_TRIALS trial_result · 2024-01-29Clinical Trial Update: Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts [Phase 4]
A Phase 4 clinical trial evaluating diuretics versus afterload reduction for managing HeartLogic alerts in heart failure patients is current…
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FDA approval · 2024-01-22FDA Approved: VALSARTAN — Supplemental Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approved a supplemental application from Unichem Pharmaceuticals (USA), Inc. for valsartan (generic valsartan) under an ANDA.
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FDA approval · 2024-01-17FDA Approved: ISOSORBIDE DINITRATE AND HYDRALAZINE HYDROCHLORIDE — Original Application (A2A Integrated Pharmaceuticals)
FDA approved a generic fixed-dose combination of isosorbide dinitrate and hydralazine hydrochloride for heart failure, manufactured by A2A I…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Natriuresis-Guided Diuretic Therapy in Patients With Acute Heart Failure With Reduced Ejection Fraction and Chronic Kidney Disease [Phase 4]
Phase 4 trial evaluating natriuresis-guided diuretic therapy in patients with acute heart failure with reduced ejection fraction and chronic…
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CLINICAL_TRIALS trial_result · 2024-01-11Clinical Trial Update: C-Pulse® System: A Heart Assist Device Clinical Study [NA]
Clinical trial update for the C-Pulse System heart assist device; the study was terminated with results posted.
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FDA approval · 2024-01-10FDA Approved: PERINDOPRIL ERBUMINE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for Perindopril Erbumine from Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Intravenous Thyroxine for Heart-Eligible Organ Donors [Phase 3]
Phase 3 clinical trial evaluating intravenous thyroxine for heart-eligible organ donors has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: COmparing arNi and Ace For Improving Erectile Dysfunction in mEN With reduCed Ejection Fraction Heart Failure [Phase 3]
A Phase 3 trial comparing arNi and Ace for improving erectile dysfunction in men with reduced ejection fraction heart failure has completed …
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FDA approval · 2024-01-08FDA Approved: ENALAPRIL MALEATE — Original Application (Aurobindo Pharma Limited)
FDA approved the original application for enalapril maleate from Aurobindo Pharma Limited, a generic version of enalapril for cardiovascular…
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: The Effects of Sacubitril/Valsartan on Cardiac Oxygen Consumption and Efficiency of Cardiac Work in Heart Failure Patients [Phase 4]
A Phase 4 trial evaluated the effects of Sacubitril/Valsartan on cardiac oxygen consumption and efficiency of cardiac work in patients with …
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FDA approval · 2023-12-27FDA Approved: METOPROLOL SUCCINATE — Supplemental Application (Nivagen Pharmaceuticals, Inc.)
FDA approved a supplemental application for metoprolol succinate (Toprol-XL) under an ANDA from Nivagen Pharmaceuticals.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: STOP-CA (Statins TO Prevent the Cardiotoxicity From Anthracyclines) [Phase 2]
Phase 2 STOP-CA trial tested whether statins can prevent cardiotoxicity from anthracycline chemotherapy in patients with heart failure; resu…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Digoxin Short Term Treatment Assessment Randomized Trial in AHF [Phase 3]
A Phase 3 randomized trial assessing short-term digoxin treatment in acute heart failure is underway, with status currently unknown.