Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Safety and Performance of INVICTA Ventricular DF4 LEADS With Active Fixation-(APOLLO) [NA]
The APOLLO study evaluating INVICTA Ventricular DF4 active-fixation leads has completed. It investigates safety and performance in patients …
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA [NA]
Clinical trial comparing stepped care versus center-based cardiopulmonary rehabilitation for older frail adults in rural Massachusetts has c…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
This clinical trial assesses the feasibility, efficacy, and adherence of telemedicine-enabled, home-based cardiac rehabilitation in patients…
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FDA approval · 2025-07-23FDA Approved: VOSTALLY — Original Application (Rosemont Pharmaceuticals LLC)
The FDA approved VOSTALLY (ramipril) from Rosemont Pharmaceuticals LLC through an original application, introducing a branded ramipril produ…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure [Phase 3]
Phase 3 multi-center trial comparing ferric derisomaltose to no intravenous iron in iron-deficient patients with symptomatic chronic heart f…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Trial of Low-intensity Anticoagulation to Reduce GI or Other Bleeding Complications With Equivalent Therapeutic Efficacy in HeartMate 3 LVAD Patients [Phase 4]
This clinical trial entry describes a Phase 4 study evaluating low-intensity anticoagulation to reduce gastrointestinal and other bleeding e…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Association Between the Sit-To-Stand Test and the Prognosis of Patients With Heart Failure
This clinical trial update describes a study evaluating whether the sit-to-stand test is associated with prognosis in patients with heart fa…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Vaccination Against Influenza Pre-discharge in Heart Failure [Phase 4]
Phase 4 clinical trial evaluating influenza vaccination given before discharge in patients with heart failure; the study is currently active…
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CLINICAL_TRIALS withdrawal · 2025-07-23Clinical Trial Update: Baroreflex Activation Therapy in Left Ventricular Assist Device Patients Study [NA]
A clinical trial evaluating baroreflex activation therapy in patients with left ventricular assist devices for heart failure has been withdr…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Treatment of Pulmonary Hypertension in High-risk Cardiac Surgery Patients Using Inhalational and Intravenous Agents [NA]
Clinical trial update evaluating inhalational and intravenous therapies for pulmonary hypertension in high-risk cardiac surgery patients. Th…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Effects of Upgrading From Right Ventricular Pacing to Cardiac Resynchronization Therapy and Comparison With Dual-Chamber Defibrillator
The study evaluated upgrading from right ventricular pacing to cardiac resynchronization therapy and compared outcomes to a dual-chamber def…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: The Influence of Probiotics on Metabolome and Heart Rate Variability in Heart Failure of Structure Heart Disease [NA]
A Chang Gung Memorial Hospital trial investigates whether probiotic supplementation alters the metabolome and heart rate variability in pedi…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Short and Long Term Prognosis of Patients Admitted to the ED With Acute Heart Failure
This clinical trial, sponsored by the University of Monastir, is currently recruiting to evaluate the short- and long-term prognosis of pati…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Electronic Device Implantation Through Remote Guidance [NA]
Completed clinical trial evaluating implantation of electronic devices (defibrillators) with remote guidance via telemedicine for heart fail…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Informational Nudge to Improve Heart Failure Prescribing [NA]
This clinical trial update describes an informational nudge intervention intended to improve prescribing practices for heart failure; the st…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Effects of IMT on Cardiac Resynchronization Therapy [NA]
A completed clinical trial evaluating the effects of IMT in patients undergoing cardiac resynchronization therapy.
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Evaluating Residual Congestion at Discharge in Acute Heart Failure Patients
Clinical Trial Update indicates the study evaluating residual congestion at discharge in patients with acute heart failure is currently recr…
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FDA approval · 2025-07-17FDA Approved: FUROSEMIDE — Original Application (Aurobindo Pharma Limited)
FDA approves Aurobindo Pharma Limited's original ANDA for furosemide, a generic loop diuretic. The approval covers the generic product for i…
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EMA approval · 2025-07-17EMA Authorised: Ivabradine Zentiva (ivabradine hydrochloride) — Zentiva, k.s.
The EMA authorised Ivabradine Zentiva (ivabradine hydrochloride) for use in angina pectoris and heart failure; Marketing authorization holde…
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FDA approval · 2025-07-17FDA Approved: SACUBITRIL AND VALSARTAN — Original Application (Camber Pharmaceuticals, Inc.)
FDA approves Camber Pharmaceuticals' original-application generic sacubitril/valsartan for the treatment of heart failure.
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Project 4: ACHIEVE PATHFINDER [NA]
This entry notes that Project 4: ACHIEVE PATHFINDER is currently recruiting for a heart failure study at Henry Ford Health System.
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Furoscix in Heart Failure Patients With Diuretic Resistance [Phase 2]
Phase 2 trial of Furoscix (furosemide) in heart failure patients with diuretic resistance has completed and results have been posted.
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FDA approval · 2025-07-16FDA Approved: SACUBITRIL AND VALSARTAN — Original Application (Novadoz Pharmaceuticals LLC)
FDA approved the original application (ANDA213748) for a generic sacubitril/valsartan combination from Novadoz Pharmaceuticals LLC.
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FDA approval · 2025-07-16FDA Approved: SACUBITRIL AND VALSARTAN — Original Application (Novugen Pharma (USA) LLC)
FDA approved the original application for a generic Sacubitril and Valsartan product by Novugen Pharma (USA) LLC, enabling a generic version…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: A Study to Evaluate Breathing Muscle Training in Cardiac Rehab [NA]
A Mayo Clinic-sponsored clinical trial is evaluating breathing muscle training as part of cardiac rehabilitation; the study is currently rec…