Heart Failure
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: REDUCED FUNCTIONALITY AND KINESIOPHOBIA IN PATIENTS WITH HEART FAILURE: USE OF ALTERNATIVE THERAPEUTIC STRATEGIES [NA]
This clinical trial update describes a study in heart failure patients (NYHA class III/IV) exploring alternative therapeutic strategies, inc…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: MRI Assessment of Pulmonary Edema in Acute Heart Failure
A University of Alberta-led clinical trial is evaluating MRI as a tool to assess pulmonary edema in patients with acute heart failure, and t…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: HIDRAdenitis Suppurativa and HEART Disease
This ClinicalTrials.gov entry reports an active, not-recruiting trial sponsored by Herlev and Gentofte Hospital investigating hidradenitis s…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 OUS Study) [NA]
Clinical trial update for the Gradient Denervation Technologies 'Pulmonary Artery DenerVation' study (PreVail-PH2 OUS) in heart failure pati…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: A Study of Vericiguat in People With Breast Cancer and Cancer Therapy-Related Cardiac Dysfunction [Phase 2]
A Phase 2 clinical trial is evaluating vericiguat in people with breast cancer who have cancer therapy-related cardiac dysfunction; the stud…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Corheart 6: Long-term Cohort Study [NA]
Ongoing recruitment for Corheart 6, a long-term cohort study in heart failure sponsored by the China National Center for Cardiovascular Dise…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: COgnitioN With VERiciGuat Evaluation in Heart Failure [Phase 2]
A Phase 2 clinical trial evaluating cognition with vericiguat in patients with heart failure is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)
Clinical trial update on estimating cardiovascular risk in patients with Crohn's disease and ulcerative colitis. Enrollment is by invitation…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Impella Reverse Remodeling in End-Stage Heart Failure
This clinical trial is recruiting to evaluate the Impella heart pump's ability to reverse remodeling in end-stage heart failure.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Investigating Myocardial Remodelling in the Failing Human Heart
A recruiting clinical trial at Oslo University Hospital is investigating myocardial remodeling in individuals with heart failure.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Microbiota-Inflammation-Brain Axis in Heart Failure: New Functional Food for the Prevention of undeRnutrition in Older [NA]
A clinical trial update describes a functional food designed to prevent undernutrition in older adults by modulating the microbiota-inflamma…
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: Observational Study on the Patient's Ability to Use a Digital Platform in Heart Failure
A completed observational study evaluating patients' ability to use a digital platform in the context of heart failure.
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Percutaneously Delivered Automated Continual Fluid Removal System in Patients With Advanced Diuretic-Resistant Heart Failure [NA]
This entry reports a clinical trial evaluating a percutaneous automated continual fluid removal system for advanced diuretic-resistant heart…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Optisure Lead Post Approval Study
The Optisure lead post-approval study sponsored by Abbott Medical Devices has been terminated, and results have been posted (2025-07-30).
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: The Italian Alliance for Cardiovascular Rehabilitation and Prevention (ITACARE-P) Registry: An Observational Study on Cardiac Rehabilitation in Patients With Coronary Disease or Heart Failure
An observational registry (ITACARE-P) assessing cardiac rehabilitation approaches for patients with coronary disease or heart failure, inclu…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Acute Kidney Injury Genomics and Biomarkers in TAVR Study
Clinical trial update on genomics and biomarkers for acute kidney injury in patients undergoing transcatheter aortic valve replacement (TAVR…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: The Improving ATTENDance to Cardiac Rehabilitation Trial [NA]
Completed clinical trial assessing approaches to improve attendance at cardiac rehabilitation; results were posted on 2025-07-29.
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: The Predictive Value of Dobutamine Echo-stress in the Clinical Response to CCM Therapy in Advanced HF
This clinical trial evaluates whether dobutamine echo-stress testing can predict the clinical response to cardiac contractility modulation t…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Semaglutide in Patients Undergoing Transcatether Aortic Valve Replacement [Phase 3]
A Phase 3 clinical trial evaluating semaglutide in patients undergoing transcatheter aortic valve replacement (TAVR) for aortic stenosis and…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Quantifying New Heart Muscle Cells [NA]
This clinical trial update from Weill Medical College of Cornell University shows that recruitment is ongoing. The study targets individuals…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: In Vivo Quantitative Mapping of Mitochondrial Cardiac Membrane Potential in Heart Failure
This clinical trial update outlines an in vivo method to quantitatively map mitochondrial cardiac membrane potential in heart failure, asses…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients [NA]
A clinical trial led by the West Virginia School of Osteopathic Medicine is evaluating lifestyle medicine approaches to chronic disease mana…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Effects of a Wed-based FRAIL-SM Program Among Patients With Heart Failure [NA]
This entry describes a web-based FRAIL-SM program being studied in patients with heart failure. The trial status is not yet recruiting.
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FDA approval · 2025-07-25FDA Approved: SPIRONOLACTONE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approves Camber Pharmaceuticals' generic spironolactone under an original application (ANDA 217761).
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: BIO|CONCEPT.Amvia Study [NA]
A completed clinical trial (BIO|CONCEPT.Amvia Study) sponsored by Biotronik Australia evaluated treatment for bradycardia and heart failure;…