Heart Failure
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Carotid Ultrasound in the Evaluation of Heart Failure [NA]
A completed clinical trial investigated the use of carotid ultrasound in evaluating heart failure; the provided excerpt does not include tri…
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: Comparison Between Lung Ultrasound and Chest Radiography for Acute Dyspnea [NA]
A completed clinical trial comparing lung ultrasound to chest radiography for evaluating acute dyspnea. The study included patients with con…
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FDA approval · 2016-04-04FDA Approved: CARVEDILOL — Supplemental Application (Aurobindo Pharma Limited)
FDA approves a supplemental application for carvedilol from Aurobindo Pharma Limited, enabling continued market supply of this generic produ…
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CLINICAL_TRIALS research · 2016-04-01Clinical Trial Update: REVADE : Right Ventricular Function and Exercise in Left Ventricular Assist Device Patients : Echocardiographic Study [NA]
This is an update on an echocardiographic study examining right ventricular function and exercise in left ventricular assist device patients…
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CLINICAL_TRIALS research · 2016-04-01Clinical Trial Update: Registry of Patients With Acute Dyspnea in the Emergency Department
A completed registry study of patients presenting with acute dyspnea in the emergency department, focusing on heart failure and COPD.
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: The Effect of Simvastatin Therapy on the Expression of Procoagulant and Inflammatory Markers in Heart Failure [EARLY_Phase 1]
A phase 1 trial evaluated the effect of simvastatin on procoagulant and inflammatory markers in patients with heart failure; the study has c…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Extended Drug Utilization Study Among Patients Exposed to Ticagrelor, Clopidogrel and Prasugrel
This clinical trial update reports the completion of an extended drug utilization study evaluating adverse events among patients exposed to …
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Acute Feedback on Left ventrIcular Lead Implantation Location for Cardiac Resynchronization Therapy [NA]
A completed clinical trial (NCT01996397) from Oslo University Hospital reported acute feedback on left ventricular lead placement location f…
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CLINICAL_TRIALS research · 2016-03-31Clinical Trial Update: Determine Return on Investment in Heart Failure Remote Monitoring Program [NA]
Clinical trial update on determining the return on investment for a remote monitoring program in heart failure; the trial status is unknown …
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CLINICAL_TRIALS research · 2016-03-31Clinical Trial Update: RESponders and QUadripolar LV Lead in CRT
This clinical trial update discusses the use of a quadripolar left-ventricular lead in cardiac resynchronization therapy for heart failure. …
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: A Study of Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure [Phase 2]
Phase 2 clinical trial of a genetically targeted enzyme replacement therapy for advanced heart failure has completed, per the trial update f…
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CLINICAL_TRIALS trial_result · 2016-03-22Clinical Trial Update: Interleukin (IL)-1 Blockade in Acute Heart Failure (Anakinra ADHF) [Phase 2, Phase 3]
Phase 2/3 study evaluating interleukin-1 blockade with anakinra in acute heart failure has completed. Trial results were posted in March 201…
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CLINICAL_TRIALS trial_result · 2016-03-22Clinical Trial Update: Outlook Quality of Life Intervention [NA]
This clinical trial update indicates that results have been posted after completion for an outlook quality-of-life intervention, involving c…
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Dual Site Left Ventricular (LV) Pacing [NA]
The update reports termination of a dual-site left ventricular pacing trial and notes that results were posted in March 2016.
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FDA approval · 2016-03-21FDA Approved: CARVEDILOL — Supplemental Application (Glenmark Pharmaceuticals Inc., USA)
The FDA approved Glenmark Pharmaceuticals' supplemental application for carvedilol, clearing a generic formulation for regulatory sale. This…
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CLINICAL_TRIALS trial_result · 2016-03-18Clinical Trial Update: Cardiac Rehabilitation of Heart Failure Patients by Telemedicine [Phase 4]
This document reports the termination of a Phase 4 clinical trial evaluating telemedicine-delivered cardiac rehabilitation for heart failure…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Marathon, Genetics, Inflammation and the Cardiovascular System: MAGIC-Trial [NA]
Completed clinical trial (MAGIC-Trial) conducted at Technical University of Munich exploring genetics and inflammation in cardiovascular dis…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Ischemic Cardiomyopathy [Phase 1, Phase 2]
Clinical trial update on a phase 1/2 study evaluating human umbilical cord-derived mesenchymal stem cells for ischemic cardiomyopathy. The c…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Epidemiology of Cardiotoxicity in Children With Cancer
A completed clinical trial update examining the epidemiology of cardiotoxicity in children treated for cancer.
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CLINICAL_TRIALS trial_result · 2016-03-14Clinical Trial Update: Buspirone as a Potential Treatment for Recurrent Central Apnea [Phase 3]
Phase 3 trial evaluating buspirone for recurrent central sleep apnea in heart failure patients was terminated; results were posted in 2016.
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CLINICAL_TRIALS withdrawal · 2016-03-11Clinical Trial Update: A Study Evaluating Biomarkers in Participants With Heart Failure (MK-0000-344) [Phase 1]
A Phase 1 study evaluating biomarkers in participants with heart failure (MK-0000-344) sponsored by Merck Sharp & Dohme LLC has been withdra…
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CLINICAL_TRIALS research · 2016-03-09Clinical Trial Update: Novel Vascular Biomarkers Behaviour and Clinical Value in Heart Failure and CRT
This document provides an update on a clinical trial researching novel vascular biomarkers and their potential clinical value in chronic hea…
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FDA approval · 2016-03-08FDA Approved: FUROSEMIDE — Supplemental Application (Phlow Corporation)
FDA approved a supplemental application for furosemide submitted by Phlow Corporation.
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CLINICAL_TRIALS research · 2016-03-08Clinical Trial Update: Training Intervention in Heart Failure and Frail Elderly Population [NA]
A clinical trial update describes a training intervention study targeting heart failure patients and frail elderly individuals, sponsored by…
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CLINICAL_TRIALS research · 2016-03-08Clinical Trial Update: Tomography Positron Emission Assessment of the Impact of Cardiac Rehabilitation on Coronary Endothelial Function in Cardiac Failure [NA]
This completed clinical study used tomography-based PET imaging to evaluate whether cardiac rehabilitation improves coronary endothelial fun…