Heart Failure
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CLINICAL_TRIALS research · 2016-05-18Clinical Trial Update: Prognostic and Diagnostic Value of Biomarkers and Cardiac Functional Parameters in Patients With Chronic Heart Failure
This clinical trial update investigates the prognostic and diagnostic value of biomarkers and cardiac functional parameters in patients with…
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CLINICAL_TRIALS research · 2016-05-18Clinical Trial Update: Optimizing Strategy of Coronary Revascularization in Patients With Multivessel Lesions Combined Heart Failure [NA]
Clinical trial update on optimizing revascularization strategy in patients with multivessel disease and heart failure; current status is unk…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Eplerenone in Heart Failure Treatment
A clinical trial evaluating eplerenone for heart failure treatment has completed, with indications including heart failure, acute myocardial…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Beta3 Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure [Phase 2]
Phase 2 clinical trial evaluating the beta-3 adrenergic agonist mirabegron for chronic pulmonary hypertension secondary to heart failure.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Iron in Congestive Heart Failure [Phase 3]
A Phase 3 trial evaluating iron therapy in patients with heart failure and iron deficiency anemia was terminated, as reported by the Univers…
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CLINICAL_TRIALS research · 2016-05-13Clinical Trial Update: Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) [Phase 3]
Phase 3 Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) has completed; the update describes a trial evaluating strategies to prevent …
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CLINICAL_TRIALS research · 2016-05-13Clinical Trial Update: Natural History of Coronary Heart Disease
The document notes the completion of a National Heart, Lung, and Blood Institute study on the natural history of coronary heart disease. It …
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CLINICAL_TRIALS withdrawal · 2016-05-13Clinical Trial Update: Sympathetic Innervation of the Heart and Cardiac Resynchronization Therapy(CRT)
The clinical trial on sympathetic innervation of the heart and cardiac resynchronization therapy has been withdrawn. It was sponsored by Uni…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Estrogen, Cytokines and Heart Failure in Women [NA]
This clinical trial update from NHLBI notes the completion of a study investigating the effects of estrogen and cytokines on heart failure i…
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Better Effectiveness After Transition - Heart Failure [NA]
Clinical trial has completed. The study evaluated effectiveness after transition in heart failure.
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Automated Hovering for Congestive Heart Failure Patients: A Pilot Study [NA]
A pilot clinical trial from the University of Pennsylvania evaluating automated hovering for patients with heart failure has completed.
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CLINICAL_TRIALS withdrawal · 2016-05-11Clinical Trial Update: Immunoadsorption and Immunoglobulin Substitution for Heart Failure After Myocardial Infarction [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating immunoadsorption and intravenous immunoglobulin substitution for heart failure after myocardial infarc…
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CLINICAL_TRIALS research · 2016-05-11Clinical Trial Update: Bowditch Revisited: Defining the Optimum Heart Rate Range in Chronic Heart Failure [NA]
An update on a University of Leeds clinical trial investigating the optimum heart rate range in chronic heart failure; the current trial sta…
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Pilot Study of the QI Device for Monitoring of Patients With Congestive Heart Failure
A pilot study evaluating the QI Device for monitoring patients with heart failure has completed.
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CLINICAL_TRIALS research · 2016-05-05Clinical Trial Update: Cardiac Function and Inspiratory Muscles Performance
This clinical trial update discusses a study evaluating cardiac function and inspiratory muscle performance in individuals with heart failur…
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FDA approval · 2016-05-04FDA Approved: EPLERENONE — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved a supplemental application for eplerenone from Mylan Pharmaceuticals, updating the approved product label for this generic …
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: Effects of Dietary Nitrate Supplementation on Cardiorespiratory Control in Chronic Heart Failure [Phase 4]
Phase 4 trial assessing the effects of dietary nitrate supplementation on cardiorespiratory control in chronic heart failure has completed.
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CLINICAL_TRIALS trial_result · 2016-04-29Clinical Trial Update: Determining When Patients Hospitalized With Acute Heart Failure Can Be Safely Sent Home (The DECIDE Study)
This completed clinical trial evaluated criteria for safely discharging patients hospitalized with acute heart failure. The study aims to gu…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Reducing 30-day Readmissions in Patients With Heart Failure Through Pharmacist Discharge Medication Services [NA]
A completed clinical trial evaluating pharmacist discharge medication services to reduce 30-day readmissions in patients with heart failure.
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FDA approval · 2016-04-26FDA Approved: CARVEDILOL — Supplemental Application (Advagen Pharma Ltd)
FDA approved a supplemental application for carvedilol filed by Advagen Pharma Ltd, resulting in an additional authorization for the product…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: Slow Continuous Ultrafiltration Using Central vs Peripheral Line: Feasibility of Implementation, Safety and Efficacy in Acute Heart Failure Syndromes. [NA]
The study compares central versus peripheral line access for slow continuous ultrafiltration in acute heart failure, evaluating feasibility,…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: The Relationship Between the Flow of Arteriovenous Fistula and Cardiac Function in Haemodialysis Patients
A completed clinical trial evaluated the relationship between arteriovenous fistula flow and cardiac function in patients undergoing haemodi…
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FDA approval · 2016-04-26FDA Approved: CARVEDILOL — Supplemental Application (Sandoz Inc)
FDA approved Sandoz Inc's supplemental application for carvedilol (CARVEDILOL).
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CLINICAL_TRIALS trial_result · 2016-04-22Clinical Trial Update: The Effect of Omega-3 Polyunsaturated Fatty Acids in Congestive Heart Failure [Phase 3]
A Phase 3 trial evaluating omega-3 polyunsaturated fatty acids in heart failure was terminated with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-04-21Clinical Trial Update: Effects of Left Ventricular Pacing Optimilization on Cardiac Perfusion, Contractile Force, and Clinical Performance in Patients With Ventricular Dysfunction and Heart Failure [NA]
Clinical trial update noting the completion of a study evaluating the effects of left ventricular pacing optimization on cardiac perfusion, …