Heart Failure
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: The Effect of Glucagon-Like Peptide-1 (GLP-1) on Pulmonary Vascular Resistance (PVR) in Patients With Heart Failure [Phase 1]
Phase 1 trial evaluating the effect of glucagon-like peptide-1 on pulmonary vascular resistance in patients with heart failure has completed…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Patient-centered Care Transitions in Heart Failure: A Pragmatic Cluster Randomized Trial [NA]
A completed pragmatic cluster-randomized trial evaluating patient-centered care transitions for heart failure.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: A Novel Automated & Comprehensive Approach for Ventricular Function Assessment in Heart Failure
This clinical trial update reports the completion of a novel automated and comprehensive approach for assessing ventricular function in pati…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: The BOSS Study: An Acute Evaluation of Anatomical and Geometric Changes Using the Bladder on a Stick System (BOSS) [NA]
This entry reports a completed status for the BOSS study, a clinical trial evaluating anatomical and geometric changes using the Bladder on …
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: An Intervention to Improve Function in Severe Cardiopulmonary Illness [NA]
This document reports a completed clinical trial testing an intervention intended to improve function in people with severe cardiopulmonary …
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: Efficacy, Safety and Tolerability of Serelaxin When Added to Standard Therapy in AHF [Phase 3]
A Phase 3 trial evaluating the addition of serelaxin to standard therapy in acute heart failure has completed and posted results for efficac…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluating metformin for cardioprotective and metabolic effects in patients with chronic heart failure and diabe…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Thyroid Hormone Replacement for Subclinical Hypothyroidism and Chronic Heart Failure (ThyroHeart-CHF) [Phase 4]
Phase 4 clinical trial update on thyroid hormone replacement for patients with subclinical hypothyroidism and heart failure; the current sta…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Acute Congestive Heart Failure Urgent Care Evaluation
The clinical trial evaluating urgent care evaluation for acute heart failure has completed.
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FDA approval · 2018-03-23FDA Approved: METOPROLOL SUCCINATE — Original Application (Zydus Pharmaceuticals (USA) Inc.)
FDA approved the original application for METOPROLOL SUCCINATE (generic) from Zydus Pharmaceuticals (USA) Inc., authorizing its marketing as…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: DPP-4 Inhibitor and Serum BNP Level of Diabetic Patients With Congestive Heart Failure [Phase 4]
Phase 4 clinical trial evaluating the effect of a DPP-4 inhibitor on serum BNP levels in diabetic patients with congestive heart failure; th…
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CLINICAL_TRIALS research · 2018-03-22Clinical Trial Update: Program Evaluation of Telehomecare: TeLeCare Study
Clinical trial update on the TeLeCare telehomecare program evaluating management of heart failure and chronic obstructive pulmonary disease;…
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CLINICAL_TRIALS research · 2018-03-22Clinical Trial Update: Interactive Patient's Assistant - LUCY
This document is a clinical trial update for the Interactive Patient's Assistant - LUCY (NCT03474315) sponsored by the Medical University of…
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CLINICAL_TRIALS withdrawal · 2018-03-20Clinical Trial Update: The Effect of Yoga on Cardiac Sympathetic Innervation Evaluated by I-123 mIBG [NA]
The clinical trial investigating the effect of yoga on cardiac sympathetic innervation in heart failure with systolic dysfunction has been w…
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Frailty Assesment in the Congestive Heart Failure Clinic
A clinical trial update describes frailty assessment in a congestive heart failure clinic; the trial status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2018-03-13Clinical Trial Update: Applying Telemedicine in a Model of Implementing Cardiac Rehabilitation in Heart Failure Patients [NA]
This clinical trial update reports the completion of a study evaluating telemedicine to implement a cardiac rehabilitation program for patie…
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CLINICAL_TRIALS trial_result · 2018-03-13Clinical Trial Update: Clinical Evaluation Of The Nano Lv Lead System In Chronic Situation (LENEA) [Phase 2, Phase 3]
Clinical trial LENEA evaluated the Nano LV Lead System for chronic heart failure in Phase 2 and Phase 3 and has been terminated.
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CLINICAL_TRIALS research · 2018-03-09Clinical Trial Update: Sildenafil in US Heart Failure Patients (SilHF-US) [Phase 3]
Phase 3 clinical trial update on sildenafil for US heart failure patients with pulmonary hypertension.
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease
The clinical trial evaluated NT-proBNP as a diagnostic biomarker for chronic heart failure in patients with chronic obstructive pulmonary di…
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CLINICAL_TRIALS trial_result · 2018-03-01Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Shenfu Zhusheye in Patients With Acute Heart Failure [Phase 4]
This clinical trial update reports the completion of a Phase 4 study evaluating the efficacy and safety of Shenfu Zhusheye in patients with …
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CLINICAL_TRIALS trial_result · 2018-03-01Clinical Trial Update: QUARTO-II Study to Evaluate the Management of Patients Resynchronized With the QuartetTM LV Quadripolar Lead
The QUARTO-II trial evaluating resynchronization therapy with the Quartet LV quadripolar lead in heart failure patients has completed, with …
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CLINICAL_TRIALS research · 2018-03-01Clinical Trial Update: Classification of Heart Failure in Children
An update on a clinical trial focused on classifying heart failure in pediatric patients.
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: Cardiovascular Improvements With MV ASV Therapy in Heart Failure [NA]
A trial evaluating MV ASV therapy in heart failure was terminated, with results posted in 2018 showing cardiovascular improvements.
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: The HeartWare™ Ventricular Assist System as Destination Therapy of Advanced Heart Failure: the ENDURANCE Trial [NA]
Clinical trial update for the HeartWare Ventricular Assist System as destination therapy in advanced heart failure; ENDURANCE trial complete…
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CLINICAL_TRIALS withdrawal · 2018-02-28Clinical Trial Update: Treatment With IV Iron in Hospitalized Patients With Severe Heart Failure But Without Iron Deficiency [Phase 4]
A Phase 4 clinical trial evaluating intravenous iron in hospitalized patients with severe heart failure without iron deficiency has been wit…