Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2018-05-07Clinical Trial Update: Cardiovascular Health Study (CHS) Events Follow-up Study
A completed follow-up update on the Cardiovascular Health Study evaluating long-term cardiovascular events and outcomes.
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Sildenafil Versus Placebo in Chronic Heart Failure [Phase 3]
This update reports a Phase 3 trial comparing sildenafil to placebo in patients with heart failure (with associated pulmonary hypertension) …
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FDA approval · 2018-05-04FDA Approved: VALSARTAN — Original Application (Unichem Pharmaceuticals (USA), Inc.)
FDA approves the original (generic) application for valsartan from Unichem Pharmaceuticals (USA), Inc., making a generic valsartan product a…
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: Cardiac MRI for Optimal Heart Failure Outcomes With CRT Upgrades [Phase 1]
This is an update on a Phase 1 trial using cardiac MRI to optimize outcomes in chronic heart failure patients receiving CRT upgrades.
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FDA approval · 2018-04-30FDA Approved: BUMETANIDE — Original Application (Zydus Pharmaceuticals (USA) Inc.)
FDA approved Bumetanide as a generic via Original Application (ANDA 202900), confirming bioequivalence to the reference product. It is indic…
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CLINICAL_TRIALS research · 2018-04-30Clinical Trial Update: Integrated Primary Care for Diabetes and Cardiovascular Disease [NA]
This entry provides information on an ongoing clinical trial from the University of Sao Paulo General Hospital evaluating integrated primary…
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CLINICAL_TRIALS withdrawal · 2018-04-24Clinical Trial Update: Influence of Anesthesia on Mechanical Efficiency of Left Ventricle in Patients Undergoing Open Heart Surgery [Phase 4]
A Phase 4 clinical trial evaluating the influence of anesthesia on left-ventricular mechanical efficiency in patients undergoing open-heart …
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CLINICAL_TRIALS research · 2018-04-24Clinical Trial Update: Exercise-based Cardiac Rehabilitation Program on Hospitalized Heart Failure Patients Submitted to Cardiac Transplantation [NA]
An update on a clinical trial evaluating an exercise-based cardiac rehabilitation program for hospitalized heart failure patients who are ca…
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FDA approval · 2018-04-23FDA Approved: SAMSCA — Supplemental Application (Otsuka America Pharmaceutical, Inc.)
FDA approved a supplemental application for Samsca (tolvaptan) from Otsuka America Pharmaceutical.
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL) [NA]
Clinical trial update for the ENDURANCE supplemental trial evaluating the HeartWare Ventricular Assist System in chronic heart failure; stud…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Microcirculation in Venoarterial Extracorporeal Membrane Oxygenation Life Support
This clinical trial update reports the completion of a study on microcirculation in venoarterial extracorporeal membrane oxygenation (VA-ECM…
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure [Phase 2]
A Phase 2 trial evaluating metformin for improving myocardial efficiency in patients with heart failure has completed.
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Cardiac Uptake of Metformin, Visualized by Positron Emission Tomography [Phase 1]
Phase 1 study evaluating cardiac uptake of metformin visualized by PET in patients with systolic heart failure; the trial status is complete…
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CLINICAL_TRIALS research · 2018-04-20Clinical Trial Update: Metformin Pharmacokinetics in Patients With Chronic and Acute Heart Failure [Phase 4]
This clinical trial update reports on the pharmacokinetics of metformin in patients with chronic and acute heart failure (Phase 4).
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CLINICAL_TRIALS trial_result · 2018-04-18Clinical Trial Update: Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects [Phase 1]
Phase 1 pharmacokinetic study assessing within-subject variability of ER torsemide 20 mg tablets in healthy subjects, sponsored by Sarfez Ph…
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CLINICAL_TRIALS withdrawal · 2018-04-18Clinical Trial Update: Treating Heart Failure With Enhanced External Counterpulsation (EECP)
This clinical trial evaluating enhanced external counterpulsation (EECP) for heart failure has been withdrawn.
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FDA approval · 2018-04-17FDA Approved: SODIUM NITROPRUSSIDE — Original Application (Mylan Institutional LLC)
FDA approved the original application for sodium nitroprusside from Mylan Institutional LLC, introducing a generic version of this vasodilat…
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CLINICAL_TRIALS research · 2018-04-17Clinical Trial Update: Heart TIMING - Heart Transplantation IMagING
This is a clinical trial update for the Heart TIMING study evaluating imaging-guided heart transplantation using magnetic resonance imaging;…
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CLINICAL_TRIALS trial_result · 2018-04-12Clinical Trial Update: Effects of 'NHGDoc' on Quality of Care [NA]
A completed clinical trial assessing NHGDoc's effect on quality of care in heart failure.
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: Post Market Clinical Follow-up of CRT-DX Therapy With Lumax 640/740 HF-T
Post-market clinical follow-up of the Lumax 640/740 HF-T CRT-DX therapy completed in patients with atrial fibrillation and heart failure.
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CLINICAL_TRIALS trial_result · 2018-04-10Clinical Trial Update: Frailty: Prevalence and Response to Left Ventricular Assist Device Therapy in Older Heart Failure Patients
This clinical trial update reports the prevalence of frailty among older heart failure patients and how they respond to left ventricular ass…
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FDA approval · 2018-04-09FDA Approved: VALSARTAN — Original Application (SQUARE PHARMACEUTICALS LIMITED)
The FDA approved Square Pharmaceuticals Limited's original application for valsartan (generic valsartan).
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CLINICAL_TRIALS research · 2018-04-09Clinical Trial Update: The Evaluation and Treatment of Elevated Left-Sided Filling Pressures by Balloon Inflation Within the IVC [NA]
Clinical trial update on evaluating and treating elevated left-sided filling pressures using balloon inflation within the inferior vena cava…
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CLINICAL_TRIALS research · 2018-04-09Clinical Trial Update: Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs)
Clinical trial update for the Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) sponsored by NHLBI; the study s…
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: SCREEN-HFL (SCReening Evaluation of the Evolution of New Heart Failure) - a Longitudinal Study
SCREEN-HFL is a longitudinal study evaluating the evolution of new heart failure. The study, sponsored by Monash University, has completed.