Heart Failure with Mid-range Ejection Fraction
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy [NA]
A completed clinical trial evaluating the SGLT-2 inhibitor dapagliflozin in patients with amyloid cardiomyopathy across heart failure phenot…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Selenium Intervention Registry Randomized Trial in Heart Failure [Phase 3]
A Phase 3 randomized trial evaluating selenium supplementation in patients with various forms of heart failure is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: CMR T1 Mapping for Diagnosis of Cardiac Amyloidosis
Completed clinical trial evaluating cardiac magnetic resonance T1 mapping for diagnosing cardiac amyloidosis.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Clinical Trial to Evaluate the Efficacy and Safety in Concomitant Administration of Macitentan and Dapagliflozin in Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction (HFmrEF and HFpEF) and Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) [Phase 4]
Phase 4 trial evaluating concomitant administration of macitentan and dapagliflozin in patients with heart failure with mid-range and preser…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease [NA]
Clinical trial update for a randomized study evaluating the Enhancor System, a pulmonary artery denervation device, in patients with combine…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Evaluation of the Effects of Sauna Therapy on Congestion and Loop Diuretic Use in Patients With Heart Failure With Reduced or Moderately Reduced Ejection Fraction [NA]
Registry entry for a clinical trial evaluating sauna therapy to reduce congestion and loop diuretic use in patients with heart failure with …
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Predicting Heart Failure Outcomes With Biomarkers and Imaging
A completed clinical trial evaluating whether circulating biomarkers and imaging findings can predict outcomes across different forms of hea…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Assessment of CCM in HF With Higher Ejection Fraction [NA]
Clinical trial update on Cardiac Contractility Modulation (CCM) for heart failure across multiple ejection fraction subtypes; the study is c…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure
Clinical trial registry update for a Biomechanical Precision Medicine Registry in patients with and without heart failure; the study is curr…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: US Benchmarking Clinical Study
Sponsor eMyosound SAS reports that the US benchmarking clinical study is currently recruiting participants for conditions including heart fa…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study [Phase 3]
ERASe-Trial, a Phase 3 study evaluating ertugliflozin to reduce arrhythmic burden in patients with heart failure and ICD/CRT devices, has be…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Spironolactone in the Treatment of Heart Failure [Phase 3]
A Phase 3 trial evaluating spironolactone for heart failure with mid-range or preserved ejection fraction has been terminated.
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Transcutaneous Vagus Nerve Stimulation in Heart Failure [NA]
Completed clinical trial evaluating transcutaneous vagus nerve stimulation for heart failure, including preserved and mid-range ejection fra…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Demographic, Clinical, Biological, Treatment Characteristics and Cardiovascular Events of Patients With Heart Failure in Vietnam: a Multicenter Prospective Observational Study
A multicenter prospective observational study in Vietnam collecting demographic, clinical, biological, treatment characteristics, and cardio…
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CLINICAL_TRIALS research · 2024-10-31Clinical Trial Update: The Effect of Sacubitril/valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients with Ischemic Heart Failure with Mid-range Ejection Fraction [Phase 3]
A Phase 3 trial comparing sacubitril/valsartan to ramipril in ischemic heart failure with mid-range ejection fraction is currently recruitin…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure [Phase 3]
Phase 3 clinical trial evaluating the safety and efficacy of pulmonary artery denervation for pulmonary hypertension associated with left he…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: The Effect of Oxygen Supplementation in Training in Heart Failure Patients on Aerobic Performance and Quality of Life [NA]
A completed clinical trial evaluating whether oxygen supplementation during training improves aerobic performance and quality of life in pat…
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CLINICAL_TRIALS trial_result · 2023-03-07Clinical Trial Update: Empagliflozin on the Function of Left Atrium in Heart Failure With Mildly Reduced or Preserved Ejection Fraction [Phase 4]
Phase 4 clinical trial updating the effects of empagliflozin on left atrial function in heart failure with preserved or mildly reduced eject…
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CLINICAL_TRIALS research · 2018-06-14Clinical Trial Update: A ComPrehensive, ObservationaL Registry of Heart FaiLure With Mid-range and Preserved EjectiON Fraction
An observational registry study focusing on heart failure with mid-range and preserved ejection fraction has completed.