Headache
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Sign up freeTop drugs studied for this disease
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FDA approval · 2025-01-21FDA Approved: BUTALBITAL, ASPIRIN, AND CAFFEINE — Supplemental Application (LGM PHARMA SOLUTIONS, LLC)
The FDA approved a supplemental application for the generic fixed-dose combination of butalbital, aspirin, and caffeine. The product is manu…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: The Use of Virtual Reality Applications in Tension-Type Headaches [NA]
A completed clinical trial evaluating the use of virtual reality applications for managing tension-type headaches.
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Combine Effect Of Myofascial Release Technique and Ocular Muscle Exercise Among University Students [NA]
This completed clinical trial investigates the combined effect of myofascial release technique and ocular muscle exercises on headache sympt…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C) [Phase 3]
Phase 3 trial update showing completion of a study evaluating two digital therapeutics for preventing episodic migraine in patients on CGRP …
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vulvodynia
A completed clinical trial update examining personality, defences, central sensitization, and trauma in women with fibromyalgia, chronic mig…
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CLINICAL_TRIALS withdrawal · 2024-12-03Clinical Trial Update: Analgesic Effects of Ultrasound-guided Dry-Needling Therapy for Neck and Head Pain [NA]
A clinical trial investigating ultrasound-guided dry-needling therapy for neck and head pain has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-11-29Clinical Trial Update: A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache [Phase 4]
A Phase 4 trial comparing IV acetaminophen versus IV ketorolac for emergency department treatment of generalized headache has been withdrawn…
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FDA approval · 2024-11-21FDA Approved: BUTALBITAL, ASPIRIN, AND CAFFEINE — Supplemental Application (Lannett Company, Inc.)
The FDA approved a supplemental ANDA from Lannett Company to market a generic Butalbital, Aspirin, and Caffeine product.
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FDA approval · 2024-11-21FDA Approved: BUTALBITAL, ASPIRIN, CAFFEINE AND CODEINE PHOSPHATE — Supplemental Application (Amneal Pharmaceuticals of New York, LLC)
FDA granted supplemental approval for Amneal's generic product containing butalbital, aspirin, caffeine, and codeine phosphate.
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FDA approval · 2024-11-21FDA Approved: IBUPROFEN — Supplemental Application (Actavis Pharma, Inc.)
The FDA approved a supplemental application for ibuprofen from Actavis Pharma, Inc.
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches [NA]
A clinical trial evaluating combined transcranial magnetic stimulation and therapy for headaches following mild traumatic brain injury is cu…
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CLINICAL_TRIALS withdrawal · 2024-11-13Clinical Trial Update: Sphenopalatine Ganglion Block for the Treatment of Post-Stroke Headache [Phase 2]
A Phase 2 clinical trial evaluating sphenopalatine ganglion block for post-stroke headache has been withdrawn.
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Efficacy of Nerve Block Versus Botox in Chronic Migraine Management [NA]
This clinical trial update reports a head-to-head comparison of nerve block versus Botox for chronic migraine management, with recruitment o…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches
This clinical trial assesses the efficacy of a Medrol Dose Pack (methylprednisolone) for acute post-concussive headaches and is currently re…
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: Percutaneous Needle Electrolysis (PNE) on the Concha of the Ear [NA]
This clinical trial is recruiting to test percutaneous needle electrolysis (PNE) applied to the ear concha for headaches.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Provider-Targeted Behavioral Interventions to Prevent Unsafe Opioid Prescribing for Acute Pain in Primary Care [NA]
A completed clinical trial evaluating provider-targeted behavioral interventions to prevent unsafe opioid prescribing for acute pain in prim…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache [Phase 1]
A Phase 1 trial evaluating Onabotulinumtoxin A (Botox) for persistent post-stroke and vascular headache was withdrawn.
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Open Label, 6-month Study for High Frequency and Chronic Migraine,
This clinical trial update describes an open-label, 6-month study for high-frequency and chronic migraine. The trial is currently active but…
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CLINICAL_TRIALS research · 2024-08-20Clinical Trial Update: COACT Study: CGRPmAbs + OnabotulinumtoxinA Assessment of Chronic Migraine Treatments Study [Phase 4]
Phase 4 study assessing chronic migraine treatments by combining CGRP monoclonal antibodies with onabotulinumtoxinA; current status is activ…
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: Transnasal Versus Suprazygomatic SPG Block in Persistant Idiopathic Facial Pain
A completed clinical trial comparing transnasal versus suprazygomatic SPG block for persistent idiopathic facial pain.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: New-onset Severe Headache After Covid-19 Vaccine
A completed clinical trial update reports new-onset severe headaches following COVID-19 vaccination, indicating a potential safety signal th…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Intravenous Fluids in Benign Headaches Trial [Phase 4]
A Phase 4 trial evaluating intravenous fluids for benign headaches has completed, with results posted in 2024.
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: Investigating the Impact of Acupuncture on the Quality of Life of Primitive Headaches Patients [NA]
A clinical trial is investigating acupuncture's impact on quality of life for patients with headaches and migraines. The study is currently …
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Relation Between Forward Head Posture and Incidence of Headache in Obese Adults
This entry reports the completion of a clinical trial investigating the relationship between forward head posture and the incidence of heada…
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine [Phase 3]
A Phase 3 clinical trial comparing Compazine (prochlorperazine) versus ketamine for headache treatment in the emergency department was termi…