Headache
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches [Phase 1]
A Phase 1 clinical trial evaluating repetitive transcranial magnetic stimulation for post-concussion headaches is currently in the recruitme…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room [Phase 3]
Phase 3 trial evaluating CLORazepate for acute migraine treatment in the emergency room has been terminated. The update does not report effi…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Different Intraperitoneal Pressures on Optic Nerve Sheath Diameter in Laparoscopic Surgeries [NA]
A clinical trial evaluating how different intraperitoneal pressures during laparoscopic surgery influence optic nerve sheath diameter as a p…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Efficacy of Manuel Therapy and BETY in Patients With Temporomandibular Dysfunction Related Headache [NA]
This entry reports the completion of a clinical trial evaluating Manuel Therapy and BETY for headaches associated with temporomandibular dis…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: The Relationship Between Smartphone Use and Headache and Posture Disorders in University Students
A completed clinical trial investigating the relationship between smartphone use and headache and posture-related disorders in university st…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Intranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid Hemorrhage [Phase 4]
A Phase 4 clinical trial is evaluating intranasal sphenopalatine ganglion blockade for headaches following aneurysmal subarachnoid hemorrhag…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: The Effect of Osteopathic Treatment on Craniocervico-Mandibular Dysfunction [NA]
This clinical trial update indicates that a study evaluating osteopathic treatment for craniocervico-mandibular dysfunction is currently rec…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Occipital Nerve Stimulation in Chronic Migraine [NA]
University College London is conducting a trial of occipital nerve stimulation for chronic migraine. The study is currently not recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Steroids in Occipital Nerve Block for Treatment of Headache [Phase 4]
A Phase 4 clinical trial evaluating the use of steroids in occipital nerve blocks for headache treatment has completed.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: The Effect of Sphenopalatine Ganglion Block on Headache and Vasalgia [NA]
A completed clinical trial evaluated the effect of a sphenopalatine ganglion block on headache and vasalgia.
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Effect of Hormones on Frequency of Headache and Brain Structure and Function in Puberty
An update on a clinical trial studying puberty-related hormone therapy and its impact on headache frequency and brain structure/function, cu…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Effects of Photobiomodulation With Superpulsed Laser and Dual Wavelengths in Children and Adolescents [NA]
A clinical trial investigating photobiomodulation with a superpulsed laser using dual wavelengths in children and adolescents, aimed at faci…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Placebo Impacts Sleep and Pain Modulation in Chronic Pain [NA]
A University of Maryland, Baltimore trial is investigating how placebo affects sleep and pain modulation in people with chronic pain and hea…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: The BETY-Biopsychosocial Questionnaire (BETY-BQ) in Individuals With Temporomandibular Dysfunction-Related Headache
An ongoing clinical trial evaluating the BETY-Biopsychosocial Questionnaire (BETY-BQ) in individuals with temporomandibular disorder-related…
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FDA approval · 2025-05-09FDA Approved: ASCOMP WITH CODEINE — Supplemental Application (LGM PHARMA SOLUTIONS, LLC)
The FDA approved a supplemental application for ASCOMP WITH CODEINE, a combination product of butalbital, aspirin, caffeine, and codeine pho…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: 0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications for Headache Treatment [Phase 3]
Phase 3 trial investigating 0.5% bupivacaine injected into the lower cervical muscles for headache treatment, comparing with intravenous med…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Assessment of the Effectiveness of Virtual Reality as a Learning Tool for Relaxation Techniques in Reducing Pediatric Migraines and Tension Type Headache [NA]
A clinical investigation is evaluating whether virtual reality-based relaxation training can reduce migraines and tension-type headaches in …
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire
This clinical trial update reports the cross-cultural adaptation of the Headache Disability Questionnaire into Turkish and assesses its reli…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Outcomes After Surgery for Degenerative Cervical Radiculopathy in Patients with Concurrent Headache
A completed clinical trial evaluating outcomes after surgical treatment for degenerative cervical radiculopathy in patients who also have he…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Effect of Parcetamol in Headach [Phase 3]
A Phase 3 clinical trial evaluating paracetamol for headache is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Cannabidiol 133mg + Cannabigerol 66mg + Tetrahydrocannabinol 4mg Vs Placebo As Adjuvant Treatment in Chronic Migraine - [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating a CBD/CBG/THC combination as adjuvant therapy for chronic migraine and related headaches was terminated.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Brain Structural Abnormalities in Patients with Post-COVID-19 Headache
A completed clinical trial from the University of Pecs evaluated brain structural abnormalities in patients with post-COVID-19 headache.
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Safety and Efficacy Predimenol for Headache [Phase 2]
A Phase 2 clinical trial evaluating Predimenol for headaches has completed and reported safety and efficacy findings.
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Sphenopalatine Ganglion Block and Cold Induced Headaches [Phase 1]
Phase 1 clinical trial evaluating sphenopalatine ganglion block for cold-induced headaches; the study is currently active but not recruiting…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine [NA]
A clinical trial evaluated whether sumatriptan affects levcromakalim-induced symptoms in people with migraine, and the study has completed.