Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: A Study of T3011 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A clinical trial update for T3011 administered intratumorally in advanced solid tumors, including phase 1 and phase 2 cohorts.
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CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: Radiation and Cetuximab Plus Intratumoral EGFR Antisense DNA in Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating radiation and cetuximab with intratumoral EGFR antisense DNA in locally advanced head and neck squamous cell carc…
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: The Quarterback Trial: Reduced Dose Radiotherapy for HPV+ Oropharynx Cancer [Phase 3]
Phase 3 trial evaluating reduced-dose radiotherapy for HPV-positive oropharyngeal cancer has posted results.
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: Docetaxel and Capecitabine With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase 2 trial evaluating docetaxel and capecitabine for recurrent or metastatic head and neck squamous cell carcinoma was terminated; result…
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CLINICAL_TRIALS trial_result · 2022-08-23Clinical Trial Update: Platinum-Cetuximab Combined With Docetaxel or With 5FU in Patients With Recurrent/Metastatic HNSCC [Phase 2]
Phase 2 trial evaluating platinum- cetuximab with docetaxel or with 5-FU in recurrent/metastatic head and neck squamous cell carcinoma has c…
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CLINICAL_TRIALS trial_result · 2022-08-19Clinical Trial Update: Phase II Trial of Carboplatin, 5-FU and Cetuximab in Elderly Fit (no Frailty) Patients With Recurrent/Metastatic HNSCC [Phase 2]
Phase II trial evaluating carboplatin, 5-FU, and cetuximab in elderly fit patients with recurrent/metastatic head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Selected De-escalation Radiotherapy for Postoperative Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating selected de-escalation radiotherapy for postoperative head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2022-07-21Clinical Trial Update: Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase I/II trial evaluating metformin in combination with cisplatin and radiation for head and neck squamous cell carcinoma has completed …
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CLINICAL_TRIALS trial_result · 2022-07-05Clinical Trial Update: Nimotuzumab Combined With Neoadjuvant Chemotherapy in the Treatment of Resectable LA HNSCC [Phase 2]
Phase 2 clinical trial update evaluating Nimotuzumab combined with neoadjuvant chemotherapy for resectable locally advanced head and neck sq…
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CLINICAL_TRIALS trial_result · 2022-05-25Clinical Trial Update: Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 3]
A Phase 3 study evaluating GSK3359609 in combination with pembrolizumab and 5-FU-platinum chemotherapy for recurrent or metastatic head and …
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 (PD-L1) Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 3]
A Phase 3 trial evaluating GSK3359609 in combination with pembrolizumab for PD-L1-positive recurrent or metastatic head and neck squamous ce…
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CLINICAL_TRIALS trial_result · 2022-05-10Clinical Trial Update: AF CRT +/- Nimorazole in HNSCC [Phase 3]
Phase 3 trial update for nimorazole added to chemoradiation in locally advanced HPV-negative head and neck squamous cell carcinoma; status a…
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CLINICAL_TRIALS trial_result · 2022-04-21Clinical Trial Update: Afatinib and Pembrolizumab for Head and Neck Squamous Cell Carcinoma (ALPHA Study) [Phase 2]
Phase 2 trial update on afatinib plus pembrolizumab for head and neck squamous cell carcinoma (ALPHA Study) completed.
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)] [Phase 2]
Phase 2 translational biomarker-driven umbrella study in head and neck squamous cell carcinoma and head and neck neoplasms completed.
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CLINICAL_TRIALS trial_result · 2022-03-25Clinical Trial Update: Trial of Neoadjuvant Therapy With Paclitaxel and Carboplatin in Operable Locally Advanced Head and Neck Cancer Patients [Phase 2]
Phase 2 trial evaluating neoadjuvant paclitaxel and carboplatin in operable locally advanced head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2022-03-21Clinical Trial Update: DAHANCA 27 Transoral Laser Microsurgery for T1a Glottic Cancer [Phase 2]
Phase 2 trial update for transoral laser microsurgery in T1a glottic cancer within head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2022-03-10Clinical Trial Update: Screening Trial of Nivolumab With Image Guided, Stereotactic Body Radiotherapy (SBRT) Versus Nivolumab Alone in Patients With Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) [Phase 2]
Phase 2 trial comparing nivolumab with image-guided SBRT versus nivolumab alone in metastatic head and neck squamous cell carcinoma has been…
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CLINICAL_TRIALS trial_result · 2022-03-09Clinical Trial Update: Tolerability and Efficacy of UV1 Vaccine in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Planned for First-line Treatment With Pembrolizumab [Phase 2]
A Phase 2 trial evaluating tolerability and efficacy of the UV1 vaccine in patients with recurrent or metastatic head and neck squamous cell…
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CLINICAL_TRIALS trial_result · 2022-03-03Clinical Trial Update: Single-agent Capecitabine as Metronomic Chemotherapy in LAHNSCC (CMHN) [Phase 3]
A Phase 3 trial investigating single-agent capecitabine as metronomic chemotherapy for head and neck squamous cell carcinoma is currently re…
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CLINICAL_TRIALS trial_result · 2022-01-25Clinical Trial Update: Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck [Phase 2]
This Phase 2 trial evaluated chemotherapy with or without erlotinib in patients with metastatic or recurrent head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2022-01-21Clinical Trial Update: The Optimization of Antiemetic Regimen for C-RINV in LA-HNSCCs [Phase 2]
Phase 2 trial update on optimizing antiemetic regimen for radiotherapy-induced nausea and vomiting in locally advanced head and neck squamou…
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CLINICAL_TRIALS trial_result · 2022-01-20Clinical Trial Update: Single-arm Study With Bimiralisib in Patients With HNSCC Harboring NOTCH1 Loss of Function Mutations [Phase 2]
Phase 2 single-arm trial of bimiralisib in head and neck squamous cell carcinoma with NOTCH1 loss-of-function mutations was terminated; resu…
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CLINICAL_TRIALS trial_result · 2022-01-12Clinical Trial Update: Study of Camrelizumab in Combination With Apatinib Mesylate Plus Albumin-bound Paclitaxel and Cisplatin as the First Line Treatment of Recurrent or Metastatic, UnresectableHead and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating camrelizumab in combination with apatinib mesylate, albumin-bound paclitaxel, and cisplatin as first-line therapy f…
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CLINICAL_TRIALS trial_result · 2021-12-13Clinical Trial Update: The Study to Evaluate Toripalimab (JS001) in Patients With Advanced GC, ESCC, NPC, HNSCC [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating toripalimab (JS001) in advanced gastric cancer and multiple squamous cell carcinomas including esophagea…
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CLINICAL_TRIALS trial_result · 2021-11-29Clinical Trial Update: Sintilimab Combined With Chemotherapy and SBRT in Limited Metastatic Head and Neck Squamous Cell Carcinoma (LM-HNSCC) [Phase 2]
Phase 2 trial evaluating sintilimab with chemotherapy and SBRT for limited metastatic head and neck squamous cell carcinoma.