Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Study of ALE.C04 in Patients With Head and Neck Cancer [Phase 1, Phase 2]
The Phase 1/Phase 2 study of ALE.C04 for head and neck cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating celecoxib added to surgery and radiation for advanced head and neck cancer; the study was terminated with results p…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin [Phase 1]
Phase 1 trial evaluating the safety and tolerability of Onalespib in combination with radiation therapy and cisplatin for locoregionally adv…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer [Phase 1]
Seagen's SEA-TGT (SGN-TGT) Phase 1 safety study in advanced cancers has been terminated. The study enrolled patients across multiple cancer …
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Phase II Multi-centered Study of Perioperative Ivonescimab Versus Pembrolizumab Combined with Standard of Care (SOC) in Patients with Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase II multi-center study comparing perioperative Ivonescimab to Pembrolizumab plus standard of care in patients with resectable, locally …
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers [Phase 1]
Phase 1 study of cosibelimab (CK-301) as a single-agent therapy in adults with advanced cancers; the trial status is active but not recruiti…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC [Phase 1]
Phase 1 trial evaluating radiotherapy in combination with atezolizumab prior to surgical resection for HPV-unrelated head and neck squamous …
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Navigation vs Usual Care for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC [NA]
Clinical trial update comparing navigation to usual care for delivering timely adjuvant therapy in locally advanced head and neck squamous c…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: The Use of "Smart" Body-Weight Scales for Weight and Nutritional Monitoring in Patients With Head and Neck Cancer Undergoing Radiation Therapy [NA]
Clinical trial NCT05457478 evaluating the use of smart body-weight scales for weight and nutritional monitoring in head and neck squamous ce…
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Dose Escalation Using Hypoxia-adjusted Radiotherapy [Phase 2]
Phase 2 trial evaluating dose escalation with hypoxia-adjusted radiotherapy in head and neck squamous cell carcinoma is currently recruiting…
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CLINICAL_TRIALS trial_result · 2025-01-14Clinical Trial Update: Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 trial update reports completion of a study evaluating an immunotherapy in combination with chemoradiation for advanced solid tumor…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer [Phase 2]
Phase 2 trial evaluating de-escalated adjuvant radiation with adjuvant nivolumab in intermediate-high risk HPV-positive oropharyngeal squamo…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating pepinemab in combination with pembrolizumab in recurrent or metastatic head and neck squamous cell ca…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer [Phase 2]
Phase 2 trial evaluating the combination of pembrolizumab and cabozantinib in head and neck squamous cell carcinoma reported results, with r…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer [Phase 1, Phase 2]
Phase 1/2 study assessing safety, tolerability, and preliminary efficacy of CJRB-101 in combination with pembrolizumab in selected advanced …
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC [Phase 2]
A Phase 2 trial evaluated the combination of eftilagimod alpha (IMP321) with pembrolizumab in patients with previously untreated unresectabl…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: A CR-UK Phase I Trial of LY3143921 [Phase 1]
Phase I trial update for LY3143921 sponsored by Cancer Research UK; the study is Active Not Recruiting and explores multiple cancer indicati…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous Cell Cancer [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated the combination of alisertib and pembrolizumab in RB-deficient head and neck squamous cell carcinoma; …
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Efficacy and Safety of a Third-Course of Neoadjuvant Immunochemotherapy Combined With SBRT in Locally Advanced Head and Neck Squamous Cell Carcinoma Patients With Stable Disease After Two Treatment Courses: A Single-Arm Exploratory Study [NA]
Clinical trial update on the efficacy and safety of a third course of neoadjuvant immunochemotherapy combined with SBRT for locally advanced…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHN [Phase 2]
A Phase 2 trial evaluating a preoperative immune checkpoint inhibitor in patients with primary untreated or recurrent/metastatic head and ne…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) [Phase 3]
A Phase 3 trial evaluating AK112 plus AK117 versus pembrolizumab for recurrent or metastatic head and neck squamous cell carcinoma; the stud…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck [Phase 1]
Phase Ib trial of buparlisib (BKM120) with cisplatin and radiotherapy in high-risk locally advanced squamous cell carcinoma of the head and …
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 trial update evaluating SB 11285 alone and in combination with atezolizumab in patients with advanced solid tumors, includ…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Ruxolitinib in Operable Head and Neck Cancer [Phase 2]
A Phase 2 trial evaluating ruxolitinib in operable head and neck squamous cell carcinoma was terminated, with results posted on 2024-10-30.
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports the completion of a study evaluating image-guided proton therapy for locally advanced unresectable head an…