Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Randomized Trial of Avelumab-cetuximab-radiotherapy Versus SOCs in LA SCCHN (REACH) [Phase 3]
Phase 3 randomized trial evaluating avelumab-cetuximab-radiotherapy versus standard of care in locally advanced head and neck squamous cell …
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Chemotherapy and Locoregional Therapy Trial (Surgery or Radiation) for Patients With Head and Neck Cancer [Phase 2]
A Phase 2 trial evaluating chemotherapy with locoregional therapy (surgery or radiation) for head and neck squamous cell carcinoma, includin…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Window of Opportunity Trial of Nivolumab and Tadalafil in Patients With Squamous Cell Carcinoma of the Head and Neck [EARLY_Phase 1]
This early-phase window-of-opportunity trial tests the combination of nivolumab and tadalafil in patients with head and neck squamous cell c…
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CLINICAL_TRIALS trial_result · 2025-04-20Clinical Trial Update: Transdermal Buprenorphine for the Treatment of Radiation-Induced Mucositis Pain in Head and Neck Cancer Patients [Phase 2]
Phase 2 trial evaluating the efficacy and safety of transdermal buprenorphine for radiation-induced mucositis pain in patients with head and…
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: A Phase 1b Study of WU-NK-101 in Combination With Cetuximab [Phase 1]
A Phase 1b trial evaluates WU-NK-101 in combination with cetuximab for metastatic colorectal cancer and head and neck squamous cell carcinom…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell Carcinoma [EARLY_Phase 1]
An early-phase pilot study evaluating glutamine PET imaging for head and neck squamous cell carcinoma, which has been terminated.
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: CMP-001 in Combination With Pembrolizumab in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial of CMP-001 in combination with pembrolizumab for recurrent or metastatic head and neck squamous cell carcinoma has been termin…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients [Phase 2]
Phase 2 clinical trial evaluating MIT-001 to prevent oral mucositis caused by concurrent chemoradiation in patients with head and neck squam…
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: Avelumab, Cetuximab, and Palbociclib in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1]
Phase 1 clinical trial update evaluating the combination of avelumab, cetuximab, and palbociclib in recurrent or metastatic head and neck sq…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies [Phase 1, Phase 2]
Phase 1/2 open-label study evaluating Alomfilimab (KY1044) alone and with atezolizumab in multiple advanced cancers. The trial was terminate…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors [Phase 1, Phase 2]
Clinical trial update for TT-10 and TT-4 (Portage Biotech) exploring single-agent and combination therapy in advanced solid tumors, with rec…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Evaluation of [18F]AlF-NOTA-PCP2 PET/CT for PD-L1 Detection in Malignant Tumors [Phase 1, Phase 2]
This clinical trial update describes evaluation of the PET tracer [18F]AlF-NOTA-PCP2 for PD-L1 detection across malignant tumors, including …
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors [Phase 2]
Phase 2 study evaluating the efficacy of tislelizumab and spartalizumab across multiple cancers with PD-1 high mRNA expression; the trial is…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers [Phase 1]
Phase 1 study of the oral STAT3 inhibitor TTI-101 in patients with advanced cancers has completed, with enrollment across multiple tumor typ…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Intratumoral Gemcitabine, Paclitaxel, Carboplatine and Intravenous Nivolumab for Locally Recurrence of Head and Neck Cancers [Phase 2]
Phase 2 trial update for intratumoral gemcitabine, paclitaxel, and carboplatin with intravenous nivolumab in locally recurrent head and neck…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Group-Mediated Cognitive Behavioral Resistance Exercise Intervention in Head and Neck Cancer Patients Undergoing Chemoradiation Treatment [NA]
A clinical trial evaluating a group-mediated cognitive behavioral resistance exercise intervention for locally advanced head and neck squamo…
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Erlotinib (Tarceva) During First Line Standard Platinum Containing Chemo for Advanced Squamous Cell Head and Neck Cancer [Phase 2, Phase 3]
Phase 2/3 trial evaluating erlotinib (Tarceva) with first-line platinum-containing chemotherapy for advanced head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer [EARLY_Phase 1]
Early-phase trial evaluating Tolinapant in combination with radiation for cisplatin-ineligible, previously untreated locally advanced head a…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer Patients [Phase 2]
Phase 2 trial comparing NETSPOT imaging (gallium-68 DOTATATE) with standard F-FDG-PET for detecting head and neck squamous cell carcinoma; r…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors [Phase 2]
Phase 2 trial of ladiratuzumab vedotin in multiple advanced solid tumors was terminated, with results posted in March 2025.
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of TBio-4101 (TIL) with pembrolizumab in advanced solid tumors has been terminated; the trial includes multiple indications su…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck [Phase 2]
Phase 2 trial evaluating reirradiation with pembrolizumab for locoregional inoperable recurrence or second primary head and neck squamous ce…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC [Phase 2]
Phase 2 study update on adding duvelisib to docetaxel for recurrent/metastatic head and neck squamous cell carcinoma; the trial has complete…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: sEphB4-HSA With RT+Chemo or Cetux in Patients With Intermediate to High Risk LAHNSCC [Phase 1]
This is a Phase 1 trial evaluating sEphB4-HSA with radiotherapy plus chemotherapy or cetuximab in locally advanced head and neck squamous ce…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations [Phase 2]
A completed Phase 2 trial evaluating immunotherapy in combination with a second drug in patients with progressive advanced mucosal cancers a…