Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer [Phase 1]
Phase 1 clinical trial evaluating MQ710 with and without pembrolizumab in solid tumors; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Pembrolizumab and Lenvatinib After Definitive Chemoradiation of Locally Advanced HNSCC [Phase 2]
Phase 2 trial evaluating pembrolizumab and lenvatinib after definitive chemoradiation in locally advanced head and neck squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: cDNA and Residual Disease After Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinomas [NA]
This entry notes an ongoing clinical trial hosted by Centre Jean Perrin examining cDNA and residual disease after chemoradiotherapy in local…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of CyPep-1 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic Cancers [Phase 1, Phase 2]
Phase 1/2 study evaluating the safety and preliminary efficacy of CyPep-1 in combination with pembrolizumab for advanced or metastatic cance…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Study of Chemotherapy With Cisplatin/Carboplatin, and Docetaxel With or Without Erlotinib in Patients With Head and Neck Squamous Cell Carcinomas Amenable for Surgical Resection [Phase 2]
A phase 2 trial evaluating cisplatin/carboplatin and docetaxel with or without erlotinib in patients with head and neck squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Ozone Therapy for Oral Mucositis in Patients Receiving Head and Neck Cancer Radio- and Chemotherapy [NA]
A clinical trial evaluating ozone therapy for oral mucositis in patients undergoing radiotherapy and/or chemotherapy for head and neck squam…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Quad Shot Radiotherapy in Combination With Immune Checkpoint Inhibition [Phase 2]
Phase 2 trial evaluating quad-shot radiotherapy in combination with an immune checkpoint inhibitor for advanced and recurrent head and neck …
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 study of magrolimab in combination therapy for head and neck squamous cell carcinoma was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity [Phase 3]
Phase 3 clinical trial evaluating uniform FDG-PET guided gradient dose prescription to reduce late radiation toxicity in head and neck squam…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: The BURAN Study of Buparlisib in Patients With Recurrent or Metastatic HNSCC [Phase 3]
Phase 3 BURAN study evaluating buparlisib in recurrent or metastatic head and neck squamous cell carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer [Phase 1, Phase 2]
Phase I/II study evaluating VLS-1488 in adults with advanced cancer; the trial is currently recruiting across multiple solid-tumor indicatio…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475 [Phase 2]
Phase 2 trial evaluating the combination of recombinant EphB4-HSA fusion protein with pembrolizumab has completed and results are posted.
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Phase II Trial of Magrolimab and Cetuximab With Pembrolizumab or Docetaxel for Recurrent/Metastatic Head Neck Squamous Cell Carcinoma [Phase 2]
A Phase II trial evaluating magrolimab and cetuximab with either pembrolizumab or docetaxel for recurrent/metastatic head and neck squamous …
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of HFB301001 in Adult Patients With Advanced Solid Tumors [Phase 1]
The Phase 1 trial of HFB301001 in adults with advanced solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC [Phase 2]
A Phase II clinical trial evaluating ACR-368 in combination with low-dose gemcitabine for recurrent/metastatic head and neck squamous cell c…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Cisplatin + Radiation in SCCHN and Correlation With Oxidative Stress Markers [Phase 2]
Phase 2 study evaluating cisplatin with radiation in head and neck squamous cell carcinoma and examining its relationship with oxidative str…
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: A Study of Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 study of tislelizumab in combination with investigational agents for head and neck squamous cell carcinoma; the trial is currently a…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial evaluated safety and preliminary effectiveness of BGB-A445 in combination with tislelizumab in participants with advanced…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: The Head and Neck Tumor Biobank
Clinical trial update for the Head and Neck Tumor Biobank (NCT01644786) sponsored by Maastricht Radiation Oncology; the study focusing on He…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC [Phase 2]
A Phase 2 trial evaluating the combination of PDS0101 and pembrolizumab in HPV16-positive recurrent/metastatic head and neck cancer has comp…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Completed Phase 2 trial comparing atezolizumab plus tiragolumab versus atezolizumab plus placebo as first-line treatment for PD-L1 positive …
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies [Phase 1]
Phase Ib study of TNO155 in combination with Spartalizumab or Ribociclib in selected malignancies was terminated, involving multiple indicat…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX) [Phase 1]
Phase 1b safety study of Xevinapant with weekly cisplatin and radiotherapy in unresected locally advanced head and neck squamous cell carcin…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
A Phase 2 open-label study evaluating BA3021 in patients with recurrent or metastatic head and neck squamous cell carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: A Clinical Study of SI-B001 in Combination With Paclitaxel in the Treatment of Recurrent and Metastatic HNSCC [Phase 2]
Phase 2 clinical trial evaluating SI-B001 in combination with Paclitaxel for recurrent/metastatic head and neck squamous cell carcinoma; the…