Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: HPV-E6-Specific Anti-PD1 TCR-T Cells in the Treatment of HPV-Positive NHSCC or Cervical Cancer [Phase 1]
Phase 1 trial of HPV-E6-specific anti-PD1 TCR-T cells for HPV-positive cervical cancer and head and neck squamous cell carcinoma has complet…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: A Study of SI-B001+SI-B003 Combined With Platinum-based Chemotherapy as First-line Treatment in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating SI-B001 and SI-B003 in combination with platinum-based chemotherapy as first-line treatment for recurrent …
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC [Phase 1, Phase 2]
Clinical trial update reporting completion of Phase 1/2 study evaluating EBV-specific anti-PD1 TCR-T cells for EBV-positive head and neck sq…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Intratumoral N17350 in Advanced Solid Tumors [Phase 1, Phase 2]
Update on the investigational intratumoral therapy N17350 being studied in advanced solid tumors in Phase 1 and Phase 2 trials, sponsored by…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial) [Phase 2]
A phase 2 AIM trial evaluating immune modulation with abemaciclib in head and neck squamous cell carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy [Phase 3]
A Phase 3 trial comparing afatinib to methotrexate in recurrent/metastatic head and neck squamous cell carcinoma after platinum therapy has …
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy [Phase 2]
This release provides results from a Phase 2 trial of a personalized immunotherapy for patients with recurrent or metastatic head and neck s…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: A Phase 1 Study of [225Ac]-FPI-1434 Injection [Phase 1]
A Phase 1 study of [225Ac]-FPI-1434 injection sponsored by Fusion Pharmaceuticals has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck Region
A completed clinical trial evaluated decisional conflicts, health-related quality of life, and satisfaction with care for patients with high…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: A Study of Lutetium [177Lu]-BL-ARC001 in Patients With Locally Advanced or Metastatic Lung Cancer, Breast Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors [Phase 1]
This is an update on an ongoing Phase 1 clinical trial evaluating Lutetium-177Lu-BL-ARC001 in patients with lung cancer, breast cancer, and …
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM) [NA]
A clinical trial evaluating the impact of virtual implant visualization on dosimetry for protecting potential dental implant sites in head a…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Detection of Circulating Tumor DNA in p16- Locally Advanced Head Neck Squamous Cell Carcinoma [NA]
A completed clinical trial from Centre Henri Becquerel evaluating detection of circulating tumor DNA in patients with p16-negative locally a…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation [Phase 2]
This Phase 2 clinical trial update describes a multilevel intervention to improve timely cancer detection and initiation of treatment; the s…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: Cisplatin, Nab-Paclitaxel, and Cetuximab (CACTUX) in Patients With Incurable Head and Neck Squamous Cell Carcinoma [Phase 2]
This clinical trial update reports on the Phase 2 CACTUX study evaluating cisplatin, nab-paclitaxel, and cetuximab for incurable head and ne…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 study of JAB-3312 in adults with advanced solid tumors has been completed, evaluating multiple tumor indications.
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma [Phase 1]
This is a Phase 1 trial evaluating low-dose radiotherapy plus tislelizumab in combination with afatinib as neoadjuvant therapy for surgicall…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of tipifarnib and alpelisib in adults with recurrent or metastatic head and neck squam…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial update comparing PCC (paclitaxel, carboplatin, cetuximab) with C-TPF (cetuximab, docetaxel, cisplatin, fluorouracil) in previo…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors [Phase 1]
A Phase 1 study of SGN-B6A in Chinese participants with advanced solid tumors has completed, reporting safety and preliminary activity acros…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Nivolumab for the Reversal of Squamous Dysplasia in High Risk Current and Former Smokers [Phase 2]
Phase 2 trial evaluating nivolumab for reversal of squamous dysplasia in high-risk current and former smokers; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: ABY-029 Head & Neck Trial [Phase 1]
Phase 1 trial update for ABY-029 in head and neck squamous cell carcinoma. The study is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors [Phase 3]
Phase 3 trial evaluating the duration of PD-1/PD-L1 inhibitor therapy in advanced solid tumors; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Combination Study With Eftilagimod Alpha (a Soluble LAG-3 Fusion Protein) and Pembrolizumab in Patients With Recurrent or Metastatic HNSCC [Phase 2]
This clinical trial update reports the completion of a Phase 2 study evaluating the combination of eftilagimod alpha and pembrolizumab in pa…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma [Phase 1]
Phase 1 study evaluating IRX-2 regimen with durvalumab for incurable head and neck squamous cell carcinoma has completed, including multiple…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: CD40 Agonist and PD-1 Inhibitor in HNSCC [Phase 1]
A Phase 1 study at the University of Pennsylvania is evaluating the combination of a CD40 agonist and a PD-1 inhibitor for head and neck squ…