Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-08-13Clinical Trial Update: Pembrolizumab (MK-3475) Versus Standard Treatment for Recurrent or Metastatic Head and Neck Cancer (MK-3475-040/KEYNOTE-040) [Phase 3]
Phase 3 trial comparing pembrolizumab to standard treatment for recurrent or metastatic head and neck cancer has completed with results post…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC. [Phase 1, Phase 2]
A Phase I/II trial evaluating induction chemotherapy with afatinib, carboplatin, and paclitaxel for HPV-negative head and neck squamous cell…
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: Prognostic Value of 18FDG PET/CT Textural Indices in HNSCC
The trial evaluating prognostic value of 18F-FDG PET/CT textural indices in head and neck squamous cell carcinoma has completed. The provide…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: AMG 319 in HPV Positive and Negative HNSCC [Phase 2]
Phase 2 trial of AMG 319 in HPV-positive and HPV-negative head and neck squamous cell carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2018-06-26Clinical Trial Update: Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy [Phase 2]
A phase 2 study comparing buparlisib plus paclitaxel versus placebo plus paclitaxel in recurrent or metastatic head and neck squamous cell c…
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CLINICAL_TRIALS trial_result · 2018-05-24Clinical Trial Update: Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 1]
Phase 1 trial evaluating the safety and preliminary activity of sorafenib tosylate in combination with cisplatin and docetaxel for patients …
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
Phase Ib/II study of BYL719 (alpelisib) with cetuximab in recurrent or metastatic head and neck squamous cell carcinoma was terminated; resu…
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Phase 1 and 2 Study of PX-866 and Cetuximab [Phase 1, Phase 2]
This document reports a completed Phase 1/2 clinical trial evaluating PX-866 in combination with cetuximab. The study enrolled patients with…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Study of IMC-A12, Alone or in Combination With Cetuximab, in Participants With Recurrent or Metastatic Squamous Cell Carcinoma (MSCC) of the Head and Neck [Phase 2]
Phase 2 study evaluating IMC-A12 (cixutumumab) alone or with cetuximab in recurrent or metastatic squamous cell carcinoma of the head and ne…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor [Phase 1]
A Phase 1 trial evaluating the safety and pharmacokinetics of ABBV-221 in adults with advanced solid tumors likely to overexpress EGFR was t…
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer [Phase 2]
This Phase 2 trial evaluated the combination of carboplatin, paclitaxel, cetuximab, and erlotinib for metastatic or recurrent head and neck …
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: A Retrospective Clinical Study of Apatinib in Combination With Radiotherapy / Chemotherapy Second-line and Above in the Treatment of Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 retrospective clinical study evaluating apatinib combined with radiotherapy/chemotherapy as second-line or higher treatment for recu…
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC) [Phase 2]
Phase 2 trial of pIL-12 electroporation in head and neck squamous cell carcinoma was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Combined FDG PET/CT Imaging in Response Evaluation After Radiochemotherapy in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC)
A completed clinical trial evaluating the use of combined FDG PET/CT imaging to assess response after radiochemotherapy in locally advanced …
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Ficlatuzumab, Cisplatin and IMRT in Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 1]
Phase 1 trial assessing ficlatuzumab with cisplatin and IMRT in locally advanced head and neck squamous cell carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Evaluation of the Tolerance of Afatinib in Combination With Docetaxel and Cisplatin in LAHNSCC Induction Chemotherapy [Phase 1]
This Phase 1 trial evaluates tolerability/safety of adding afatinib to docetaxel and cisplatin as induction chemotherapy for locally advance…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Reirradiation and Erbitux in the HNSCC [Phase 2]
Phase 2 clinical trial evaluating reirradiation with cetuximab in head and neck squamous cell carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC) [Phase 1]
Phase 1 trial evaluating induction chemotherapy with afatinib, ribavirin, and weekly carboplatin/paclitaxel for HPV-associated stage IVA/IVB…
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CLINICAL_TRIALS trial_result · 2017-10-23Clinical Trial Update: LUX-Head&Neck 2: A Phase III Trial of Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy [Phase 3]
Phase III trial evaluating Afatinib versus placebo for head and neck squamous cell carcinoma after chemoradiotherapy; the study was terminat…
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CLINICAL_TRIALS trial_result · 2017-10-23Clinical Trial Update: A Phase I Study to Evaluate the Safety, Tolerability and Efficacy of MEDI4736 (Durvalumab) With Tremelimumab in Head and Neck Cancer [Phase 1]
This is a completed Phase I trial evaluating the safety, tolerability and preliminary efficacy of durvalumab (MEDI4736) in combination with …
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: TumorGraft- Guided Therapy for Improved Outcomes in Head and Neck Squamous Cell Cancer- A Feasibility Study [NA]
This completed feasibility trial assessed tumor graft-guided therapy as a treatment approach for head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2017-10-16Clinical Trial Update: Phase 2 Study of GSK1363089 (Formerly XL880) in Adults With Squamous Cell Cancer of the Head and Neck [Phase 2]
Phase 2 trial of GSK1363089 (formerly XL880) in adults with head and neck squamous cell carcinoma has completed enrollment and posted result…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of cetuximab and recombinant interleukin-12 in patients with head and neck squamous ce…
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CLINICAL_TRIALS trial_result · 2017-08-28Clinical Trial Update: Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating interstitial photodynamic therapy for recurrent head and neck cancer was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2017-08-16Clinical Trial Update: The Clinical Relevance of Immune Cells and CTC in HNSCC Patients
The update discusses the clinical relevance of immune cells and circulating tumor cells in head and neck squamous cell carcinoma. It highlig…