Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma [Phase 1]
Phase 1 trial assessing trigriluzole in combination with nivolumab and pembrolizumab for various metastatic or unresectable solid tumors and…
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Pembrolizumab Plus Docetaxel for the Treatment of Recurrent or Metastatic Head and Neck Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating pembrolizumab plus docetaxel for recurrent or metastatic head and neck cancer has completed with results…
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: A Phase II Study of 250-mg ZD1839 Monotherapy in Recurrent or Metastatic or Both Recurrent and Metastatic Squamous Cell Carcinoma [Phase 2]
A Phase II study evaluating 250-mg ZD1839 (gefitinib) as monotherapy in recurrent/metastatic head and neck squamous cell carcinoma has been …
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Cetuximab+Zimberelimab in Combination With Cisplatin and Nab-paclitaxel in Resctable Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating cetuximab + zimberelimab with cisplatin and nab-paclitaxel in locally advanced, operable head and neck squamous cel…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Pirfenidone as a Radiosensitizer in the Treatment of Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating pirfenidone as a radiosensitizer in patients with head and neck squamous cell carcinoma undergoing …
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer [Phase 3]
A Phase 3 trial evaluating Monalizumab in combination with Cetuximab versus Cetuximab alone in recurrent or metastatic head and neck squamou…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Pembrolizumab in HNSCC With Residual Disease After Radiation [Phase 2]
A Phase 2 trial evaluating pembrolizumab for head and neck squamous cell carcinoma with residual disease after radiation was terminated, wit…
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CLINICAL_TRIALS trial_result · 2023-11-02Clinical Trial Update: A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents [Phase 1, Phase 2]
Phase 1/2 trial evaluating OR2805, a anti-CD163 monoclonal antibody, alone and with anticancer agents for solid tumors, with unspecified sta…
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Tissue and Hematopoietic/Mesenchymal Stem Cell for Humanized Xenograft Studies in Melanoma and Squamous Head and Neck Cancer [NA]
This ClinicalTrials.gov record reports a completed study evaluating tissue and hematopoietic/mesenchymal stem cells in humanized xenograft m…
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CLINICAL_TRIALS trial_result · 2023-10-30Clinical Trial Update: Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC [Phase 3]
Phase 3 trial evaluating pembrolizumab plus standard chemotherapy as neoadjuvant therapy for locally advanced head and neck squamous cell ca…
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CLINICAL_TRIALS trial_result · 2023-10-27Clinical Trial Update: Study of Intratumoral (IT) Ulevostinag (MK-1454) in Combination With Intravenous (IV) Pembrolizumab (MK-3475) Compared to IV Pembrolizumab Alone as the First Line Treatment of Metastatic or Unresectable, Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) (MK-1454-002) [Phase 2]
A Phase 2 trial evaluating intratumoral Ulevostinag (MK-1454) in combination with intravenous pembrolizumab versus intravenous pembrolizumab…
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin [Phase 2, Phase 3]
Phase 2/3 clinical trial update reporting results for adding durvalumab or cetuximab to radiation therapy in locoregionally advanced head an…
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin [Phase 2, Phase 3]
Phase 2/3 clinical trial comparing radiation therapy with durvalumab or cetuximab for locoregionally advanced head and neck cancer patients …
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: A Study of Apatinib and Tegafur Gimeracil Oteracil in Locally Advanced Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase 2 clinical trial studying apatinib in combination with tegafur gimeracil oteracil for locally advanced head and neck squamous cell car…
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: Non Inferiority Trial of Standard RT Versus Hypofractionated Split Course in Elderly Vulnerable Patients With HNSCC [Phase 3]
Phase 3 non-inferiority trial comparing standard radiotherapy to hypofractionated split course in elderly vulnerable patients with head and …
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CLINICAL_TRIALS trial_result · 2023-09-05Clinical Trial Update: Neoadjuvant Cadonilimab in Combination With Cisplatin and Nab-paclitaxel in Resectable Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial investigating neoadjuvant cadonilimab with cisplatin and nab-paclitaxel for resectable head and neck squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus Infection [Phase 1, Phase 2]
Phase 1/2 trial of M7824 (bintrafusp alfa) alone and in combination with TriAd vaccine and N-803 for resectable HPV-unrelated head and neck …
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: PD-1 Inhibitor Therapy Versus Radiotherapy in pCR Patients With Locally Advanced HNSCC After Neoadjuvant Immunochemotherapy [Phase 3]
A Phase 3 trial comparing PD-1 inhibitor therapy to radiotherapy in patients with locally advanced head and neck squamous cell carcinoma aft…
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: Evaluate the Efficacy and Safety of HLX10 in Combination With HLX07 in Patients With Advanced Head and Neck Tumors [Phase 2]
A Phase 2 trial evaluating HLX10 in combination with HLX07 for advanced head and neck tumors is ongoing, with unclear status.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: The Safety and Efficacy of Multiple-dose of JS004 in Subject With HNC [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating multiple-dose JS004 in head and neck cancers, assessing safety and efficacy.
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CLINICAL_TRIALS trial_result · 2023-07-28Clinical Trial Update: Calizumab Combined With Bevacizumab and Capecitabine in the Treatment of Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating Calizumab with Bevacizumab and Capecitabine for head and neck squamous cell carcinoma is ongoing; status c…
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CLINICAL_TRIALS trial_result · 2023-07-28Clinical Trial Update: A Clinical Trial of TQB2618 Injection Combined With Penpulimab Injection and Chemotherapy Versus Penpulimab Injection Combined With Chemotherapy in First-line Treatment of Relapsed/Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
Clinical trial evaluating TQB2618 with Penpulimab and chemotherapy versus Penpulimab and chemotherapy in first-line relapsed/metastatic head…
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CLINICAL_TRIALS trial_result · 2023-07-25Clinical Trial Update: Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase II trial evaluating nelfinavir with concurrent chemoradiotherapy in head and neck squamous cell carcinoma has completed with results p…
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating ficlatuzumab with or without cetuximab in cetuximab-resistant recurrent or metastatic head and neck squamous cell c…
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CLINICAL_TRIALS trial_result · 2023-07-07Clinical Trial Update: A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer [Phase 2]
Phase 2 clinical trial evaluating ONM-100 as an intraoperative fluorescence imaging agent for cancer detection has completed enrollment with…