Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports termination of the INBRX-105 in combination with pembrolizumab across multiple solid tumors, including hea…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010/LEAP-010)-China Extension [Phase 3]
Phase 3 trial evaluating pembrolizumab with or without lenvatinib as first-line therapy in PD-L1–selected recurrent or metastatic head and n…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Multi-Site Pathological Images-Guided ViT for Oral Squamous Cell Carcinoma Recurrence Prediction
A completed multi-site clinical trial evaluating a pathological images-guided ViT model to predict recurrence in oral squamous cell carcinom…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of NGM831 as a monotherapy and in combination with pembrolizumab (with or without NGM438) in advanced or metastatic solid tu…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Intensity-Modulated Radiation Therapy & Nivolumab for Recurrent or Second Primary Head & Neck Squamous Cell Cancer [Phase 2]
A Phase 2 study evaluating the combination of intensity-modulated radiation therapy with nivolumab for recurrent or second primary head and …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: JAB-3068 Activity in Adult Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A completed Phase 1/Phase 2 trial update for JAB-3068 in adults with advanced solid tumors, including Esophageal Squamous Cell Carcinoma, No…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Optimized Diffusion-Weighted Imaging for the Evaluation of Post-Treatment Squamous Cell Carcinoma in the Neck: Comparative Study With FDG PET/CT [NA]
A terminated diagnostic trial comparing diffusion-weighted imaging with FDG PET/CT for evaluating post-treatment head and neck squamous cell…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study to Evaluate NT219 Alone and in Combination with ERBITUX® (Cetuximab) in Adults with Advanced Solid Tumors and Head and Neck Cancer [Phase 1, Phase 2]
Clinical trial update reporting completion of a Phase 1/2 study evaluating NT219 alone and in combination with cetuximab (ERBITUX) in adults…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Radiotherapy Plus Xevinapant in Older Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial of radiotherapy plus Xevinapant for older patients with locally advanced head and neck squamous cell carcinoma has been suspen…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase 2 trial evaluating erlotinib and docetaxel in combination with radiation therapy for stage III/IV squamous cell carcinoma of the head …
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Pembrolizumab in Combination With Cisplatin and Intensity Modulated Radiotherapy (IMRT) in Head and Neck Cancer [Phase 2]
Phase 2 trial of pembrolizumab with cisplatin and intensity-modulated radiotherapy for head and neck squamous cell carcinoma has completed w…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Study Evaluating the Efficacy of Niraparib and Dostarlimab (TSR-042) in Recurrent/Metastatic HNSCC [Phase 2]
Phase 2 clinical trial evaluating the combination of niraparib and dostarlimab (TSR-042) in recurrent/metastatic head and neck cancer is cur…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer [Phase 1]
Phase 1 trial of nab-paclitaxel (albumin-bound paclitaxel) with carboplatin followed by chemoradiation in patients with recurrent head and n…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Cabozantinib in Combination With Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Cancer [Phase 1]
Phase 1 trial evaluating cabozantinib in combination with cetuximab for recurrent or metastatic head and neck squamous cell carcinoma has co…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurrent Head and Neck Squamous Cell Carcinoma [Phase 1]
A Phase 1 trial evaluating birinapant in combination with intensity-modulated re-irradiation therapy for locally recurrent head and neck squ…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating Bintrafusp alfa in combination with stereotactic body radiation therapy for recurrent or second primary head and …
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010) (KEYNOTE-010) [Phase 3]
This is a Phase 3 trial evaluating pembrolizumab with or without lenvatinib as first-line treatment in PD-L1–selected recurrent or metastati…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) [Phase 1]
This update reports the completion of a Phase 1 study (DUET-3) evaluating XmAb23104 in patients with selected advanced solid tumors.
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Safety, Tolerability and Pharmacokinetics Investigation of Stimotimagene Copolymerplasmid [Phase 1]
Phase 1 trial evaluating safety, tolerability, and pharmacokinetics of Stimotimagene Copolymerplasmid in multiple cancer types; the study ha…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of PRT3645 conducted by Prelude Therapeutics in patients with several advanced solid tumors has completed, including breast …
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin [Phase 2]
Phase 2 trial evaluating sodium thiosulfate to prevent cisplatin-induced ototoxicity in patients with head and neck squamous cell carcinoma …
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: Smoking Tobacco Cessation Integrated Program of Patients Treated for the Head and the Neck Cancer [NA]
Completed clinical trial evaluating a Smoking Tobacco Cessation Integrated Program for patients treated for head and neck squamous cell carc…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy [Phase 2]
Phase 2 trial evaluating tipifarnib in HRAS-mutant head and neck squamous cell carcinoma has completed, with results posted assessing safety…
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: Nivolumab Plus Pemetrexed for Head and Neck Squamous Cell Carcinoma [Phase 2]
This update notes the completion of a Phase 2 trial evaluating the combination of nivolumab and pemetrexed in head and neck squamous cell ca…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Study of ADCT-301 in Patients With Selected Advanced Solid Tumors [Phase 1]
Phase 1 trial update for ADCT-301 (camidanlumab tesirine) in selected advanced solid tumors; the study has been terminated and results have …