Head and Neck Squamous Cell Carcinoma
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Virtual Reality 3D-Surgery Modeling to Enhance Head and Neck Cancer Surgery Quality [NA]
A clinical trial is investigating virtual reality 3D-surgery modeling to enhance the quality of head and neck squamous cell carcinoma surger…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation [Phase 1]
This clinical trial update states that CLSP-1025 is being evaluated in a Phase 1 study for adults with solid tumors harboring the p53 R175H …
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
This ClinicalTrials.gov entry describes a study by A2 Biotherapeutics evaluating HLA LOH analysis and apheresis for CAR-T cell manufacturing…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Study for Identification of Immune Determinants for Response to Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma [NA]
A Yonsei University-led clinical trial update investigating immune determinants of response to nivolumab in recurrent or metastatic head and…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study [Phase 2]
A Phase 2 trial (The Knight SHIFT Study) is comparing morning versus afternoon administration of immunotherapy for advanced or metastatic so…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Comprehensive Multiomic Biomarker Evaluation Across Two Single-arm Cohorts to Elucidate Mechanisms of Response and Resistance in Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) [Phase 2]
Phase 2 clinical trial update describing two single-arm cohorts in recurrent/metastatic head and neck squamous cell carcinoma, focusing on c…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors [Phase 1]
Phase 1 study update for NRM-823 in locally advanced or metastatic refractory solid tumors, currently recruiting. The trial lists head and n…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial [Phase 2]
This document outlines a Phase 2 clinical trial (LAPP Trial) investigating the combination of lovastatin and pembrolizumab for recurrent or …
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Neoadjuvant Chemoimmunotherapy (Camrelizumab + Paclitaxel + Carboplatin) for Resectable HNSCC [Phase 2]
Phase 2 neoadjuvant chemoimmunotherapy trial for resectable head and neck squamous cell carcinoma using camrelizumab with paclitaxel and car…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: H101 Plus TACE for r/m HNSCC [Phase 2]
This entry notes a Phase 2 trial evaluating H101 in combination with transarterial chemoembolization (TACE) for recurrent/metastatic head an…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating cemiplimab in combination with low-dose paclitaxel and carboplatin f…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC [Phase 2]
A Phase 2 clinical trial is evaluating pulsed-dose chemotherapy in combination with pembrolizumab for recurrent/metastatic head and neck squ…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial update of P-MUC1C-ALLO1, an allogeneic CAR-T cell therapy, being studied in advanced or metastatic solid tumors. The study is …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Heavy Strength Training in Head and Neck Cancer Survivors [Phase 2]
Phase 2 clinical trial evaluating heavy strength training in head and neck cancer survivors is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: HPV 16-positive and/or HPV 18-positive Recurrent and/or For Patients With Metastatic Head and Neck Cancer to Evaluate GX-188E DNA Vaccination, GX-I7 and Nivolumab Combination Therapy [Phase 2]
A Phase 2 clinical trial in HPV 16/18-positive recurrent or metastatic head and neck squamous cell carcinoma evaluating a triple therapy of …
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Neoadjuvant Becotatug Vedotin Plus Pucotenlimab and Cisplatin for Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 neoadjuvant trial evaluating Becotatug Vedotin with Pucotenlimab and Cisplatin in locally advanced head and neck squamous cell carci…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma
This clinical trial update shows that a study on circulating tumor DNA (ctDNA) in locally advanced head and neck squamous cell carcinoma is …
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Longitudinal Oral Health Changes After Head and Neck Radiotherapy
ClinicalTrials.gov update describing an ongoing longitudinal study of oral health changes in patients after radiotherapy for head and neck c…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A Study of SH009 Injection in Patients With Advanced Solid Tumors. [Phase 1]
A Phase 1 clinical trial update for SH009 Injection in patients with advanced solid tumors, currently recruiting across multiple indications…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Low-Dose Radiotherapy and Anti-PD-1 Immunotherapy as Neoadjuvant Treatment for Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating neoadjuvant low-dose radiotherapy combined with anti-PD-1 immunotherapy for resectable locally advanced he…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer [Phase 1]
Phase 1 trial evaluating combining immunotherapy salvage surgery with intraoperative radiotherapy (IORT) for head and neck cancer, including…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Pembrolizumab and Radiotherapy for Oligometastatic Head and Neck Cancer [Phase 3]
Ongoing Phase 3 trial evaluating pembrolizumab with radiotherapy for oligometastatic head and neck squamous cell carcinoma is currently recr…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: A Single-arm, Phase II, Multi-center Clinical Trial of Sintilimab During the Perioperative Period in Patients With Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase II, single-arm, multicenter clinical trial evaluating the perioperative use of sintilimab in patients with resectable locally advanc…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: PDT For Induction Therapy For Head And Neck Cancer [Phase 2]
Phase 2 clinical trial update on photodynamic therapy as induction therapy for head and neck cancer. The trial is currently not yet recruiti…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating BL-B01D1 in patients with metastatic or unresectable non-small cell lung cancer and other solid tumors is …