Head and Neck Squamous Cell Carcinoma
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy [Phase 2]
Phase II biomarker-driven, open-label, single-arm, multicenter study evaluating abemaciclib in patients with recurrent or metastatic head an…
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CLINICAL_TRIALS research · 2017-08-10Clinical Trial Update: The Clinical Relevance of P16 Expressing CTCs Detection Comparing With HPV Infection in Cancer Tissue in HNSCC Patients.
This clinical trial study in head and neck squamous cell carcinoma evaluates the clinical relevance of detecting P16-expressing circulating …
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CLINICAL_TRIALS research · 2017-06-23Clinical Trial Update: the Study of Effect of Chronomodulated Chemotherapy on the Dendritic Cells Subsets in the Treatment of Advanced Nasopharyngeal Cancer [Phase 2]
Phase 2 study evaluating chronomodulated chemotherapy's effect on dendritic cell subsets in advanced nasopharyngeal carcinoma. The trial is …
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Biomakers in Tissue Samples From Patients With Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck Previously Treated With Cisplatin With or Without Cetuximab
This completed clinical trial studied biomarkers in tissue samples from patients with recurrent or metastatic head and neck squamous cell ca…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Biomarkers of Response in Blood and Tumor Tissue Samples From Patients With Unresectable Stage IV Squamous Cell Cancer of the Head and Neck Previously Treated With Cetuximab, Cisplatin, and Radiation Therapy
A completed clinical trial update describing biomarkers of response in blood and tumor tissue from patients with unresectable stage IV squam…
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CLINICAL_TRIALS research · 2017-05-08Clinical Trial Update: An Observational Study to Evaluate the Safety and Efficacy of Cetuximab in Combination With Platinum-based Chemotherapy in the First-line Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck
An observational study assessing the safety and efficacy of cetuximab in combination with platinum-based chemotherapy as first-line treatmen…
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CLINICAL_TRIALS research · 2017-05-01Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Docetaxel Polymeric Micelle (PM) in Recurrent or Metastatic HNSCC [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of a polymeric micelle formulation of docetaxel in recurrent or metastatic he…
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CLINICAL_TRIALS research · 2017-04-17Clinical Trial Update: Docetaxel and Loplatin Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced SCCHN [Phase 2]
A Phase 2 trial evaluates induction chemotherapy with docetaxel and cisplatin (Loplatin) followed by concurrent chemoradiotherapy for locall…
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CLINICAL_TRIALS research · 2016-09-28Clinical Trial Update: The Clinical Study of the Poorly Differentiated Head and Neck Squamous Cell Carcinoma
A clinical study at Beijing Tongren Hospital is investigating treatment for poorly differentiated head and neck squamous cell carcinoma; no …
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CLINICAL_TRIALS research · 2016-09-22Clinical Trial Update: A Phase 1 Dose Escalation Study of GC4419 in Combination With Chemoradiation for Squamous Cell Cancer of the Head & Neck [Phase 1]
A Phase 1 dose-escalation study of GC4419 in combination with chemoradiation for head and neck squamous cell carcinomas, including cancers o…
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CLINICAL_TRIALS research · 2016-09-14Clinical Trial Update: A Study of Pharmacodynamics of RO5083945 in Patients With Head and Neck Squamous Cell Carcinoma [Phase 1]
Phase 1 pharmacodynamics study of RO5083945 in patients with head and neck squamous cell carcinoma has completed.
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CLINICAL_TRIALS research · 2016-03-02Clinical Trial Update: Assessing Tumor Response and IMRT Treat Plan After IC Based on FDG-PET/CT for Locally Advanced HNSCC [Phase 2]
This entry reports the completion of a Phase 2 trial evaluating tumor response and IMRT planning after induction chemotherapy guided by FDG-…
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CLINICAL_TRIALS research · 2016-01-22Clinical Trial Update: State of the Art Photon Therapy Versus Particle Therapy for Recurrent Head & Neck Tumors; a Planning Study
A completed planning study comparing state-of-the-art photon therapy versus particle therapy for recurrent head and neck tumors is reported.…
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CLINICAL_TRIALS research · 2015-06-30Clinical Trial Update: Cisplatin Plus Raltitrexed or 5-fluorouracil Concurrent With Radiotherapy for Head and Neck Squamous Cell Cancer [Phase 3]
Phase 3 trial evaluating cisplatin plus raltitrexed or cisplatin plus 5-fluorouracil with radiotherapy for head and neck squamous cell carci…
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CLINICAL_TRIALS research · 2015-04-22Clinical Trial Update: The Princess Alexandra Hospital and the QIMR Berghofer Medical Research Institute Head and Neck Cancer Study
This entry updates a head and neck cancer study led by The Princess Alexandra Hospital and the QIMR Berghofer Medical Research Institute, fo…
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CLINICAL_TRIALS research · 2014-12-03Clinical Trial Update: Circulating Tumor Cells as an Early Predictive head-and -Neck Squamous-cell Carcinoma [NA]
Clinical trial update investigating circulating tumor cells as an early predictive biomarker for head and neck squamous cell carcinoma; no t…
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CLINICAL_TRIALS research · 2014-06-10Clinical Trial Update: Intensive Nutrition Counselling in Patients With Head and Neck Cancer [NA]
This document provides an update on a clinical trial evaluating intensive nutrition counseling for patients with head and neck squamous cell…
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CLINICAL_TRIALS research · 2014-06-06Clinical Trial Update: Erlotinib, Docetaxel, and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer [Phase 1]
This Phase 1 clinical trial update examines a combination regimen of Erlotinib, Docetaxel, and radiation therapy for locally advanced head a…
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CLINICAL_TRIALS research · 2013-12-09Clinical Trial Update: Trismus Prevention, Diagnosis and Management: Radiotherapy Planning, Early Detection, and Physical Therapy Intervention [NA]
A clinical trial update addressing prevention, early detection, and management of trismus in head and neck squamous cell carcinoma patients …
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CLINICAL_TRIALS research · 2013-10-24Clinical Trial Update: Proximal Molecular Effects of Concurrent Chemoradiotherapy on Head and Neck Squamous Cell Carcinoma
Clinical trial update reporting proximal molecular effects observed after concurrent chemoradiotherapy in head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2013-09-16Clinical Trial Update: Study on the Interplay Between Twist1 and Other EMT Regulators Through microRNA-29 Family.
A clinical trial update examining the interaction between Twist1 and other EMT regulators via the microRNA-29 family in head and neck squamo…
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CLINICAL_TRIALS research · 2013-04-02Clinical Trial Update: Blood Proteins in Predicting Treatment Benefit in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer
This update describes a completed clinical trial investigating whether specific blood protein biomarkers can predict treatment benefit in pa…
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CLINICAL_TRIALS research · 2013-04-02Clinical Trial Update: Biomarkers in Predicting Response to Treatment in Patients With Newly Diagnosed Stage III or Stage IV Head and Neck Cancer Treated With Carboplatin, Paclitaxel, and Radiation Therapy
Clinical trial update on biomarkers that may predict response to treatment in newly diagnosed stage III/IV head and neck cancer treated with…
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CLINICAL_TRIALS research · 2012-10-08Clinical Trial Update: Study of BKM120 in Advanced Squamous Cell Carcinoma of Head and Neck [Phase 2]
A Phase 2 clinical trial investigating buparlisib (BKM120) in advanced head and neck squamous cell carcinoma is listed. The current study st…
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CLINICAL_TRIALS research · 2012-10-02Clinical Trial Update: Evaluation of the Oncoral® Test in Epidermoid Carcinomas of the Upper Aerodigestive Tract [NA]
This clinical trial update reports an evaluation of the Oncoral Test for epidermoid carcinomas of the upper aerodigestive tract. No results …