Head and Neck Squamous Cell Carcinoma
📧 Sign up to get email alerts when something new happens for Head and Neck Squamous Cell Carcinoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: De-escalation Radiation Strategy After NAC in Combination With ICI in LAHNSCC [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating a de-escalation radiation strategy after neoadjuvant chemotherapy in combination with an immu…
-
CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Immunotherapy and Carbon Ion Radiotherapy In Solid Cancers With Stable Disease [Phase 2]
Phase 2 clinical trial exploring immunotherapy combined with carbon ion radiotherapy in solid cancers with stable disease, currently recruit…
-
CLINICAL_TRIALS research · 2024-08-20Clinical Trial Update: ARTEMIS-006: HS-20093 in Patients With Head and Neck Squamous Cell Carcinoma and Other Solid Tumors [Phase 2]
The document describes an ongoing Phase 2 study ARTEMIS-006 (HS-20093) for head and neck squamous cell carcinoma and other solid tumors. The…
-
CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors [Phase 1]
RemeGen's RC198 is being evaluated in a Phase 1 study across locally advanced unresectable or metastatic solid tumors, including melanoma, u…
-
CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Efficacy and Safety of PD-1 Plus Chemotherapy in Poorly Differentiated Locally Advanced (LA) HNSCC [Phase 2]
An ongoing Phase 2 clinical trial assessing the efficacy and safety of a PD-1 inhibitor in combination with chemotherapy for poorly differen…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Liquid Biopsy for Early DiagNosis of Squamous Cell Carcinoma of the HeAd and NeCk rEgion
This clinical trial update notes ongoing recruitment for a study evaluating a liquid biopsy approach for early diagnosis of head and neck sq…
-
CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: AK112 Plus AP Regimen for Operable Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 study evaluating AK112 in combination with an AP regimen as neoadjuvant therapy for operable locally advanced head and neck squamous…
-
CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: A Phase II Study of MRG003 Injection Combined With Pucotenlimab Injection ± Cisplatin Injection in the Neoadjuvant Treatment Locally Advanced EGFR-positive Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase II neoadjuvant trial evaluating MRG003 with Pucotenlimab, with or without cisplatin, for EGFR-positive locally advanced head and neck …
-
CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Neoadjuvant Camrelizumab With Dalpiciclib for Resectable Head and Neck Squamous Cell Carcinomas [Phase 1]
Phase 1 neoadjuvant trial combining camrelizumab with dalpiciclib for resectable head and neck squamous cell carcinoma is currently recruiti…
-
CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: AK117 (Anti-CD47) + Anti-EGFR for R/M HNSCC [Phase 2]
Phase 2 clinical trial evaluating AK117, an anti-CD47 therapy, in combination with an anti-EGFR agent for recurrent/metastatic head and neck…
-
CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: A Phase II Study of Anti-EGFR Antibody-drug Conjugate (ADC) Combine With CDK4/6 Inhibitors Posterior Line in the Treatment of Recurrent/Metastatic CDKN2A Gene Variant Head and Neck Squamous Cell Carcinoma [Phase 2]
Phase II study evaluating an anti-EGFR antibody-drug conjugate in combination with a CDK4/6 inhibitor for recurrent/metastatic head and neck…
-
CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers. [Phase 1]
Phase 1 trial update for YE-NEO-001, NantBioScience's personalized neoepitope yeast vaccine, evaluating adjuvant immunotherapy to elicit T-c…
-
CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous SCG142 TCR T cells for HPV16/52-positive squamous cell carcinomas across multiple HPV-related sites; c…
-
CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: Dose De-escalation and Sentinel LN Mapping Driven Radiotherapy of Contralateral Neck in Ipsilateral Node Positive HNSCC [NA]
This entry describes an ongoing clinical trial investigating dose de-escalation and sentinel lymph node mapping-guided radiotherapy for ipsi…
-
CLINICAL_TRIALS research · 2024-06-28Clinical Trial Update: Immunotherapy and SBRT for Metastatic Head and Neck Carcinomas [Phase 1, Phase 2]
This entry describes a Phase 1/2 clinical trial investigating immunotherapy in combination with stereotactic body radiotherapy for metastati…
-
CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: A Study of LVGN6051 Combination Therapy in Patient With Head and Neck Squamous Cell Carcinoma (HNSCC) [Phase 2]
A Phase 2 study evaluating LVGN6051 in combination therapy for head and neck squamous cell carcinoma is currently recruiting.
-
CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Identification of Pattern and Factors Affecting Recurrence in Head and Neck Carcinoma
An ongoing clinical trial at Sohag University is studying patterns and factors related to recurrence in head and neck squamous cell carcinom…
-
CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Head and Neck Squamous Cell Carcinoma (REDUCTION-I) [Phase 3]
A Phase 3 trial (REDUCTION-I) is evaluating tislelizumab with chemotherapy followed by surgery versus upfront surgery in resectable head and…
-
CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Clinically Node-negative Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial evaluating tislelizumab plus chemotherapy followed by surgery versus upfront surgery in resectable, clinically node-negative…
-
CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Neoadjuvant DaRT for Locally Advanced Oral Cavity SCC [NA]
A clinical trial update for neoadjuvant Diffusing Alpha-emitters Radiation Therapy (DaRT) in locally advanced oral cavity squamous cell carc…
-
CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinoma
This clinical trial update describes a study evaluating real-time detection of circulating tumor DNA (ctDNA) and HPV DNA in patients with hi…
-
CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors [Phase 1]
This is a Phase 1 clinical trial studying Anti-CD70 UCAR-T for relapsed or refractory solid tumors, with not yet recruiting status.
-
CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: An Open Label, Single Arm, Multicenter Phase II Study of BYL719 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck Who Failed to Respond to Platinum-based Therapy. [Phase 2]
Open-label, single-arm Phase II trial evaluating BYL719 (alpelisib) in recurrent or metastatic head and neck squamous cell carcinoma after p…
-
CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Evaluation of the Overall Quality of Life After the Neck Dissection Retro-spinal Sector (IIb), in Squamous Cell Carcinomas Clinical and Radiological N0 VADS
This clinical trial update reports an ongoing study evaluating quality of life after neck dissection in head and neck squamous cell carcinom…
-
CLINICAL_TRIALS research · 2018-03-29Clinical Trial Update: Prospective Trial of Serial CT Imaging for Evaluation of Dosimetric/Volumetric Changes During IMRT for Head/Neck Cancer
This clinical trial update from the University of Miami describes a prospective study using serial CT imaging to evaluate dosimetric and vol…