Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: HNSCC Immuno-genomics Project
A completed clinical trial update describing a project focused on immunogenomics and molecular classification of head and neck squamous cell…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: The Value of CEUS in Assessing the Response of Cervical Lymph Nodes After NACI for HNSCC
Clinical trial update on using contrast-enhanced ultrasound to assess cervical lymph node response after neoadjuvant therapy in head and nec…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Intra-arterial Chemotherapy Combined with Radiotherapy and Immunotherapy for HNSCC [Phase 2]
A Phase 2 clinical trial is evaluating intra-arterial chemotherapy combined with radiotherapy and immunotherapy for head and neck squamous c…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Study of TL117 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
Clinical trial update for TL117 in recurrent or metastatic head and neck squamous cell carcinoma (Phase 1/Phase 2); the study is currently a…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: A Clinical Trial to Evaluate Effect of IAE0972 Combined with Chemotherapy for R/M HNSCC or NPC(Note: It is Currently Phase II.). [Phase 2, Phase 3]
A clinical trial evaluating the effect of IAE0972 in combination with chemotherapy for recurrent/metastatic head and neck squamous cell carc…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Trilaciclib in Preventing Hematopoietic Suppression in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating trilaciclib to prevent chemotherapy-induced hematopoietic suppression in patients with recurrent or meta…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Patient-derived Xenograft Models of Tumor From Patients With Head and Neck Cancer
This clinical trial focuses on establishing patient-derived xenograft models using tumors from patients with head and neck squamous cell car…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Neoadjuvant Therapy of Targeted Immunotherapy Combined With Chemotherapy for Locally Advanced HNSCC [Phase 2]
Phase 2 neoadjuvant trial evaluating targeted PD-L1 immunotherapy combined with chemotherapy for locally advanced head and neck squamous cel…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Deep sequencIng in Cutaneous Squamous CEll caRciNomas [Phase 2]
Phase 2 clinical trial update exploring deep sequencing in cutaneous squamous cell carcinoma and cutaneous squamous cell carcinoma of the he…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Afatinib in Patients with Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating afatinib for patients with Fanconi anemia and advanced head and neck squamous cell carcinoma is curren…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: Study of Cemiplimab - TP Induction Chemotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck [Phase 1]
This Phase 1 trial is evaluating cemiplimab in combination with TP induction chemotherapy for locally advanced head and neck squamous cell c…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Phase II Trial of Pembrolizumab in Recurrent or Metastatic HNSCC [Phase 2]
A Phase II trial evaluating pembrolizumab for recurrent or metastatic head and neck squamous cell carcinoma is currently active but not recr…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Prospective Pilot Study Evaluating Dental Side Effects of Radiotherapy on Subjects Treated for Head and Neck Cancer [Phase 2]
A Phase 2 prospective pilot trial is investigating dental side effects from radiotherapy in head and neck cancer patients, sponsored by Jule…
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CLINICAL_TRIALS research · 2024-10-31Clinical Trial Update: Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise Training in HNSCC Patients [NA]
This clinical trial is currently recruiting to investigate whether changes in skeletal muscle mass measured on imaging can predict prognosis…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Arabic PRO Measures for Head and Neck Cancer Radiotherapy.
A trial investigating Arabic patient-reported outcome measures for radiotherapy in head and neck cancer patients; currently recruiting.
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers [Phase 3]
Phase 3 trial evaluating whether adding pembrolizumab to radiotherapy improves outcomes for newly diagnosed metastatic head and neck squamou…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Neoadjuvant Toripalimab + Chemotherapy ± Cetuximab in Locally Advanced Head and Neck Squamous Cell Carcinoma (Neo-ICT) [Phase 3]
This is a Phase 3 trial evaluating neoadjuvant toripalimab plus chemotherapy with or without cetuximab for locally advanced head and neck sq…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: A Study of Pembrolizumab (MK-3475) Plus Platinum and Gemcitabine as First Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (PIPER) [Phase 2]
Phase 2 clinical trial (PIPER) evaluating pembrolizumab plus platinum and gemcitabine as first-line therapy for recurrent/metastatic head an…
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CLINICAL_TRIALS research · 2024-09-24Clinical Trial Update: A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors [Phase 1]
Describes a Phase 1 clinical trial of SPX-303, a bispecific antibody targeting LILRB2 and PD-L1, in patients with solid tumors, including he…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy [EARLY_Phase 1]
A phase 1 study from Vanderbilt-Ingram Cancer Center is evaluating image-based, in-vivo assessment of tumor hypoxia to guide hypoxia-driven …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer Patients [Phase 3]
A multicentre Phase III trial is evaluating risk-based treatment intensification with hyperfractionated radiotherapy in head and neck squamo…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Neoadjuvant Tislelizumab in Combination With Dasatinib and Quercetin in Resectable HNSCC (COIS-01) [Phase 2]
A Phase 2 neoadjuvant trial (COIS-01) examines tislelizumab with dasatinib and quercetin for resectable head and neck squamous cell carcinom…
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CLINICAL_TRIALS research · 2024-09-03Clinical Trial Update: Surgery and Reducing Ionizing Radiation of the Unknown Primary [Phase 2]
A Phase 2 clinical trial update describes evaluating surgical management with reduced ionizing radiation for unknown primary head and neck c…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell Carcinoma
A clinical trial is evaluating neoadjuvant therapy with carboplatin, paclitaxel, and anti-PD-1 drugs to assess effects on pain, anxiety, and…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Cognitive Function in Patients With Resectable Head and Neck Squamous Cell Carcinoma
This clinical trial update notes recruitment for a neoadjuvant therapy study combining carboplatin and paclitaxel with an anti-PD-1 drug in …