Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Neoadjuvant Immunochemotherapy for LAOSCC [Phase 3]
A Phase 3 clinical trial investigating neoadjuvant immunochemotherapy for locally advanced oral squamous cell carcinoma and head and neck sq…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A two-cohort phase 1/2 clinical trial is investigating niraparib and dostarlimab with chemotherapy and radiotherapy in locally advanced head…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Induction IBI110 and Sintilimab with Chemotherapy in LA HNSCC [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial sponsored by Fudan University evaluating induction with IBI110 and Sintilimab in combination with chemoth…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Exercise Therapy in Head and Neck Squamous Cell Carcinoma (HNSCC) [NA]
This clinical trial registration describes a study evaluating exercise therapy for head and neck squamous cell carcinoma (HNSCC); the trial …
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Identifying the Predictive Factors of Response to PD-1 or PD-L1 Antagonists [NA]
A clinical trial update aimed at identifying predictive factors of response to PD-1/PD-L1 inhibitors across multiple cancers, including mela…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Personalized Nutrition Counseling and Nutritional Status of Esophageal Cancer and HNSCC Patients Undergoing CCRT
A clinical trial update indicates that a study evaluating personalized nutrition counseling and nutritional status in esophageal cancer and …
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Efficacy of an Oral Immunomodulatory Nutrient on Survival During Postoperative Concomitant Chemoradiotherapy in Head and Neck Cancer [NA]
This clinical trial update describes an oral immunomodulatory nutrient being studied for survival during postoperative concomitant chemoradi…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Tirilizumab with Albumin-bound Paclitaxel and Cisplatin for Locally Advanced Resectable Oral Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating tirilizumab in combination with albumin-bound paclitaxel and cisplatin for locally advanced resectabl…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Specific Methylation Profiles in HNSCC
This clinical trial update reports on a study at Aalborg University Hospital investigating methylation profiles in head and neck squamous ce…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Reconstruction of Cervical Lymphatic System During Head and Neck Squamous Cell Carcinoma Surgery [NA]
Registry entry for a prospective study on reconstructing the cervical lymphatic system during head and neck squamous cell carcinoma surgery,…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: PA.RI.GE. Study. The Prognostic Role of Inflammatory Circulating Biomarkers in HNSCC: a Prospective Multicentric Trial
This clinical trial studies the prognostic role of inflammatory circulating biomarkers in head and neck squamous cell carcinoma and is curre…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of the bispecific antibody MCLA-158 in patients with advanced solid tumors. Recruitme…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects with HPV Positive HNSCC. [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2a study evaluating BVAC-E6E7 in HPV-positive head and neck squamous cell carcinoma, with the t…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Study of Pembrolizumab Combined with Chemotherapy in the First Line Therapy for R/M HNSCC in China [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab combined with chemotherapy as first-line therapy for recurrent/metastatic head and neck squa…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC [EARLY_Phase 1]
This early-phase trial update shows that the PBI-MST-01 substudy AZN-05 is recruiting intratumoral microdosing of four investigational agent…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Study of TPEx Followed by a Maintenance With Avelumab and Cetuximab in First Line Recurrent or Metastatic Squamous Cell Carcinoma of the H&N [Phase 2]
This Phase 2 trial investigates TPEx chemotherapy followed by maintenance with avelumab and cetuximab as first-line treatment for recurrent …
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Nano-crystalline Megestrol Acetate for Adjuvant Treatment in High-risk Head and Neck Squamous Cell Carcinoma After Surgery. [Phase 3]
A Phase 3 trial evaluating adjuvant nano-crystalline megestrol acetate for high-risk head and neck squamous cell carcinoma after surgery; th…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers [Phase 2]
This Phase 2 trial aims to evaluate whether reducing the dosing frequency of immune checkpoint inhibitors is feasible across advanced cancer…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Hypofractionated Radiotherapy for HNSCC in Elderly Patients [NA]
This clinical trial update indicates a study evaluating hypofractionated radiotherapy for head and neck squamous cell carcinoma in elderly p…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Application of MRI Radiomics Features in Neoadjuvant Therapy of Head and Neck Squamous Cell Carcinoma
A clinical trial protocol evaluating MRI radiomics features to predict response to neoadjuvant therapy in head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Using a 3D Culture Model for Circulating Tumor Cells Combined With Molecular Bioassays in Patients With HNSCC Cancer
A clinical trial update describing a study that uses a 3D culture model for circulating tumor cells combined with molecular bioassays in pat…
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: Bone Marrow Protective Effect of Trilaciclib in Postoperative CCRT for LA-HNSCC [Phase 2]
Phase 2 clinical trial update exploring trilaciclib as a bone marrow protective agent during postoperative concurrent chemoradiation for loc…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: A Clinical Study on Neoadjuvant Treatment of Resectable Head and Neck Squamous Carcinoma With Immune-targeted Therapy and Lysogenic HSV Virus [Phase 1]
Phase 1 neoadjuvant trial assessing an immune-targeted therapy in combination with a lysogenic HSV virus for resectable head and neck squamo…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Safety and Efficacy of VB10.16 and Pembrolizumab in Patients with Head-Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating VB10.16 in combination with pembrolizumab for HPV-positive oropharyngeal squamous cell carcinoma and head-and-n…
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer [Phase 1]
Phase 1 study evaluating adding BAY 1895344 with radiation therapy to pembrolizumab for recurrent head and neck squamous cell carcinomas, ai…