Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors [Phase 2]
This Phase 2 study of BL-B01D1 in combination with a PD-1 monoclonal antibody for recurrent or metastatic head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Trial Evaluating the Tolerance and Safety of Durvalumab - RT Combination for Treatment in SCCHN [Phase 2]
Clinical trial update on the safety and tolerability of durvalumab combined with radiotherapy for head and neck squamous cell carcinoma (Pha…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: A Prospective, Multicenter, Multicohort Phase II Study: Evaluating the Efficacy and Safety of Preoperative Neoadjuvant Treatment With a PD-1 Inhibitor in Combination With Chemotherapy in Locally Advanced Laryngeal and Hypopharyngeal Squamous Cell Carcinoma [Phase 2]
Phase II multicenter study evaluating neoadjuvant therapy with a PD-1 inhibitor in combination with chemotherapy for locally advanced laryng…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC
A prospective observational study sponsored by UNC Lineberger to validate circulating HPV DNA and prognostic genomic biomarkers in HPV-assoc…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Study of NEO-201 in Solid Tumors Expansion Cohorts [Phase 1, Phase 2]
Precision Biologics is expanding cohorts in a Phase 1/2 study of NEO-201 in solid tumors, including non-small cell lung cancer, head and nec…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Induction Modified TPF Followed by Concurrent Chemoradiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck [Phase 2]
A Phase 2 clinical trial evaluating induction Modified TPF followed by concurrent chemoradiotherapy for locally advanced head and neck squam…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Molecular Imaging of DNA Damage Response by [18F]-Olaparib PET [Phase 1, Phase 2]
This is a clinical trial update for Phase 1/Phase 2 evaluation of molecular imaging of the DNA damage response using the [18F]-labeled Olapa…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Tislelizumab Combined With SBRT for the Treatment of Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating the combination of tislelizumab and SBRT for head and neck squamous cell carcinoma, currently recruiting…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck Cancer
This clinical trial update examines cisplatin-induced cochlear and vestibular damage, including hearing loss, in patients with head and neck…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Evaluation of Radiobiological Effects in Skin Toxicities Head and Neck Cancer Patients With PBS Proton Therapy [NA]
Ongoing clinical trial evaluating radiobiological effects related to skin toxicities in head and neck cancer patients treated with pencil-be…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Trial of Ibrutinib Combined With Nivolumab or Cetuximab to Treat Recurrent/Metastatic HNSCC [Phase 2]
Ongoing Phase 2 clinical trial evaluating the combination of Ibrutinib with Nivolumab or Cetuximab for recurrent/metastatic head and neck ca…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: PET/CT Follow up for Head and Neck Squamous Cell Carcinoma [NA]
A clinical trial update indicates that a study evaluating PET/CT follow-up for head and neck squamous cell carcinoma is currently recruiting…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Needs and Preferences of Patients With Head-neck Cutaneous SCC
A clinical trial investigating the needs and preferences of patients with cutaneous squamous cell carcinoma of the head and neck; the study …
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Molecular-Based Selection of Patients with Head and Neck Squamous Cell Carcinoma: Biomarker Analysis
A clinical trial update describing molecular-based selection of patients with locally advanced head and neck squamous cell carcinoma using b…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TU2218 in combination with pembrolizumab (Keytruda) in patients with advanced solid tumors is currentl…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCC [Phase 2]
A Phase 2 single-center trial is evaluating AHCC in combination with standard-of-care therapy for HPV-positive head and neck squamous cell c…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients [Phase 2]
Phase 2 clinical trial update on Voyager V1 in combination with cemiplimab in cancer patients, with conditions including melanoma, head and …
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial evaluating AP203 in patients with locally advanced or metastatic solid tumors, including non-small cell …
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2 [NA]
This ClinicalTrials.gov update describes a study investigating the role of the microbiome as biomarkers in locoregionally-advanced oropharyn…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Peritumoral Microbubbles and CEUS for SLN Detection and Biopsy in HNSCC [NA]
The study investigates peritumoral microbubbles and contrast-enhanced ultrasound for sentinel lymph node detection and biopsy in head and ne…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy
A clinical trial is recruiting elderly patients with head and neck squamous cell carcinoma undergoing radiotherapy. The study covers cancers…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Chemo-Radiotherapy Boost Treatment Guided by Perfusion MRI on Hypoxic Zones in Head and Neck Cancer [Phase 2]
Phase 2 clinical trial evaluating a chemo-radiotherapy boost guided by perfusion MRI of hypoxic zones in head and neck squamous cell carcino…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: A Trial of Nimotuzumab and Pinkiller Efficacy and Pain in Advanced Head and Neck Squamous Cell Carcinoma [Phase 4]
A Phase 4 trial of Nimotuzumab with Pinkiller for advanced head and neck squamous cell carcinoma is ongoing. The study is currently active b…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Surufatinib Combined with Envolizumab As Second-line Treatment for Recurrent/Metastatic HNSCC [Phase 2]
A Phase 2 trial evaluating surufatinib in combination with envolizumab as second-line treatment for recurrent/metastatic head and neck cance…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Cetuximab Plus Platinum and Taxane-based Chemotherapy, Followed by Avelumab and Cetuximab, as First-line Treatment for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) Patients With a PD-L1 Combined Positive Score (CPS)≥1≤19. [Phase 2]
Phase 2 clinical trial evaluating cetuximab with platinum and taxane-based chemotherapy followed by avelumab and cetuximab as first-line tre…