Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Study Evaluating a Stereotactic Boost/Treatment for Recurrent or Metastatic Cancer of the Head and Neck [Phase 1]
Phase 1 trial evaluating a stereotactic boost/treatment for recurrent or metastatic head and neck cancer; the study is currently active but …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Neoadjuvant Immunoradiotherapy in Head & Neck Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 neoadjuvant immunoradiotherapy study for head and neck cancer, currently active but not rec…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2, single-arm exploratory study evaluating a PD-L1–targeting antibody plus neoadjuvant chemotherapy for locally advanced head and ne…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of MRG003 in patients with recurrent or metastatic squamous cell carcinoma of the …
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Comparing Two Surveillance Approaches for People Who Have Received Treatment for HPV-associated Head and Neck Cancer and Show No Signs of Disease [NA]
This clinical trial compares two surveillance approaches for people previously treated for HPV-associated head and neck squamous cell carcin…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders [Phase 2]
A Phase 2 clinical trial at Oslo University Hospital is testing fecal microbiota transplantation from clinical responders in cancer patients…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Iparomlimab and Tuvonralimab Combined With SFRT and Definitive Chemoradiotherapy in Locoregionally Advanced Bulky HNSCC [Phase 2]
Phase 2 clinical trial evaluating iparomlimab and tuvonralimab in combination with SFRT and definitive chemoradiotherapy for locoregionally …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: A Randomized Controlled Trial of Spermidine for the Prevention of Radiation-Induced Xerostomia in Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma) [Phase 1, Phase 2]
A phase 1/2 randomized trial evaluating spermidine to prevent radiation-induced xerostomia in patients with head and neck cancers, including…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Finotonlimab Combined With Stapokibart in the Treatment of Recurrent/Metastatic HNSCC [Phase 1]
Phase 1 clinical trial evaluating finotonlimab in combination with stapokibart for recurrent/metastatic head and neck squamous cell carcinom…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: A Clinical Trail of KJ015 in Patients With HER2-Expressing Solid Tumors [Phase 1]
A Phase 1 trial update for KJ015 in HER2-expressing solid tumors shows the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Identification of Individual Histological and Blood Markers in Patients With Recurrent or Metastatic Upper Aerodigestive Tract Squamous Cell Carcinoma in Response to Immunotherapies [NA]
A sponsor-initiated clinical trial is recruiting to identify histological and blood biomarkers in patients with recurrent or metastatic uppe…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC [Phase 2]
This document outlines a Phase 2 trial evaluating preoperative pembrolizumab in combination with chemotherapy for resectable and recurrent h…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: An Open-label Study Using ASP-1929 Photoimmunotherapy in Combination With Anti-PD1 Therapy in EGFR Expressing Advanced Solid Tumors [Phase 1, Phase 2]
Open-label Phase 1/2 trial evaluating ASP-1929 photoimmunotherapy in combination with anti-PD1 therapy for EGFR-expressing advanced solid tu…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Noninvasive Intratumor Heterogeneity Evaluation in HNSCC
This clinical trial update describes an ongoing study evaluating noninvasive intratumor heterogeneity in head and neck squamous cell carcino…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: A Clinical Trial of Neoadjuvant Targeted Therapy, Immunotherapy, and Lysogenic HSV-Based Virotherapy in Resectable Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating neoadjuvant targeted therapy, immunotherapy, and lysogenic HSV-based virotherapy in patients with rese…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer [Phase 1]
A Phase 1 trial at the University of Chicago is evaluating a personalized, adaptive treatment approach for locally advanced head and neck sq…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy [Phase 2]
A Phase 2 clinical trial evaluating AK104 in combination with low-dose radiation for recurrent or metastatic head and neck squamous cell car…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: AK129 Combination Therapy for Advanced Solid Tumors [Phase 1, Phase 2]
AK129 is being studied in Phase 1/2 trials for multiple advanced solid tumors, including non-small cell lung cancer and head and neck squamo…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Discontinuation of Tobacco Dependence in Smoking Patients With Squamous Cell Carcinoma of the Head-neck District: Multicenter Prospective Observational Study
A multicenter prospective observational study assessing tobacco cessation in patients with head and neck squamous cell carcinoma. The study …
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies [Phase 1]
Phase 1 study of COM902, a TIGIT inhibitor, in patients with advanced malignancies is ongoing and currently not recruiting.
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: [68Ga]Ga-FAPI-46 in Staging of Head and Neck Carcinomas [Phase 2]
Phase 2 clinical trial investigating the imaging agent [68Ga]Ga-FAPI-46 for staging head and neck squamous cell carcinoma is currently recru…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck
This clinical trial is evaluating tumor-informed circulating tumor DNA (ctDNA) surveillance for detecting measurable residual disease after …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Cetuximab + Tislelizumab + Chemotherapy in the Treatment of Unresectable LA HNSCC [Phase 2]
Phase 2 clinical trial evaluating cetuximab plus tislelizumab and chemotherapy for unresectable locally advanced head and neck squamous cell…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Adjuvant Immunotherapy After Salvage Surgery in Head and Neck Squamous Cell Carcinoma [Phase 2]
This ClinicalTrials.gov entry reports a Phase 2 trial evaluating adjuvant immunotherapy after salvage surgery for head and neck squamous cel…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Chemo-radiotherapy Versus Radiotherapy in the Treatment of Salivary Glands and Nasal Tumors (IMRT or Protontherapy) [Phase 3]
Phase 3 trial comparing chemo-radiotherapy to radiotherapy alone for head and neck squamous cell carcinoma of the salivary glands and nasal …