Head and Neck Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer [Phase 2]
A Phase 2 clinical trial evaluating compartmentalized postoperative radiotherapy in head and neck cancer, currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Clinical Study to Evaluate the Efficacy and Safety of SI-B001 in the Treatment of Recurrent and Metastatic HNSCC [Phase 2]
Clinical trial update describing a Phase 2 study to evaluate the efficacy and safety of SI-B001 in recurrent and metastatic head and neck sq…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating SI-B001 plus SI-B003 with or without chemotherapy in locally advanced or metastatic head and neck squa…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors [Phase 2]
A Phase 2 clinical trial evaluating BL-B01D1, SI-B003, and their combination in patients with recurrent or metastatic head and neck squamous…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma [Phase 3]
Phase 3 trial evaluating dostarlimab versus placebo after chemoradiation in locally advanced unresected head and neck squamous cell carcinom…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas [NA]
Clinical trial is exploring de-escalation of adjuvant radiotherapy with or without chemotherapy for HPV-positive head and neck squamous cell…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Blood Biomarkers Based Screening for HPV-driven OPC [NA]
UNICANCER-sponsored trial is evaluating blood biomarker-based screening for HPV-driven cancers, including oropharyngeal cancer, with status …
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: A Study of BL-B16D1 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors [Phase 1]
Phase 1 study of BL-B16D1 for head and neck squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: The FORCE Trial Pilot: Fish Oil-enriched Nutrition for Radiotherapy in Cancer of the hEad and Neck [Phase 1, Phase 2]
The FORCE Trial Pilot is a Phase 1/2 study of fish oil-enriched nutrition given during radiotherapy for head and neck squamous cell carcinom…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy
A clinical trial is evaluating the combination of PD-1/PD-L1 immune checkpoint inhibitors with radiotherapy across several cancers to assess…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: A Study of GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as Monotherapy in Patients With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial update for GI-108, a bispecific anti-CD73-IL-2v fusion protein, being studied as monotherapy in advanced or metasta…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Improved Oral Health in Head and Neck Cancer Survivors [NA]
A clinical trial from Uppsala University focusing on improving oral health in survivors of head and neck cancer; the study is not yet recrui…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Docetaxel/Pembrolizumab in Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial evaluating the combination of docetaxel and pembrolizumab for head and neck squamous cell carcinoma is currently active but …
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: [18F]-AraG PET Imaging in LA HNSCC [EARLY_Phase 1]
This is an early-phase study evaluating [18F]-AraG PET imaging in locally advanced head and neck squamous cell carcinoma, currently not yet …
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: HPV-16 Vaccination and Pembrolizumab Plus Cisplatin for "Intermediate Risk" HPV-16-associated Head and Neck Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial update evaluating HPV-16 vaccination in combination with pembrolizumab and cisplatin for intermediate-risk HPV-16-a…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Phase I/II Trial of HCB101 in Combination With Pembrolizumab for Patients With Platinum-Refractory, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (SirH&N Trial) [Phase 1, Phase 2]
This clinical trial update concerns a Phase I/II study evaluating HCB101 in combination with pembrolizumab for platinum-refractory, recurren…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression [Phase 1, Phase 2]
A2 Biotherapeutics is evaluating A2B395, an allogeneic logic-gated CAR T therapy, in Phase 1/2 trials for solid tumors expressing EGFR and l…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Study of NX-1607 in Adults With Advanced Malignancies [Phase 1]
A Phase 1 study evaluating NX-1607 in adults with advanced malignancies is actively recruiting across multiple tumor types, including ovaria…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors [Phase 1]
Phase 1 first-in-human trial evaluating OKN4395 in combination with pembrolizumab in patients with solid tumors is currently recruiting. The…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: PDO Based Drug Sensitive Test in R/M HNSCC
A recruiting clinical trial evaluating a patient-derived organoid–based drug sensitivity test for recurrent/metastatic head and neck squamou…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Stereotactic Radiotherapy Combined With Chemotherapy or Not for Treatment of Oligometastases in HNSCC [Phase 2]
Phase 2 clinical trial evaluating stereotactic radiotherapy with or without chemotherapy for oligometastatic head and neck squamous cell car…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Predictive Biomarkers for PD-1 Inhibitor Response in Squamous Cell Carcinoma
This clinical trial update discusses predictive biomarkers for response to PD-1 inhibitors in squamous cell carcinomas, spanning esophageal,…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Influencing Factors for Physical Activity in People With Head and Neck Cancer
A completed clinical trial evaluating factors that influence physical activity in people with head and neck squamous cell carcinoma, focusin…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: Tislelizumab Combined With Chemotherapy for Different Cycles of Neoadjuvant Therapy for Locally Advanced Resectable Squamous Cell Carcinoma of the Head and Neck (NeoTempo) [Phase 2]
Phase 2 trial evaluating tislelizumab combined with chemotherapy as neoadjuvant therapy for locally advanced, resectable head and neck squam…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Neoadjuvant Immunochemotherapy and Postoperative Adjuvant Immunotherapy for Head and Neck Squamous Cell Carcinoma Invading the Skull Base [Phase 2]
A Phase 2 clinical trial assessing neoadjuvant chemoimmunotherapy followed by postoperative adjuvant immunotherapy for head and neck squamou…