Haemophilia
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CLINICAL_TRIALS research · 2017-08-02Clinical Trial Update: HEAD-US SCORING SYSTEM: Assessment of the Real-world Impact of Ultrasound [NA]
This document provides a clinical trial update on the HEAD-US scoring system and its real-world impact for monitoring shoulder health in pat…
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CLINICAL_TRIALS trial_result · 2017-07-27Clinical Trial Update: Safety and Efficacy of Turoctocog Alfa (N8) in Prevention and On-demand Treatment of Bleeding Episodes in Subjects With Haemophilia A: An Extension to Trials NN7008-3543, NN7008-3545, NN7008-3600, NN7008-3893 and NN7008-4015 [Phase 3]
Extension results from Phase 3 trials evaluating safety and efficacy of Turoctocog alfa (N8) for prophylaxis and on-demand treatment of blee…
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CLINICAL_TRIALS trial_result · 2017-07-24Clinical Trial Update: Efficacy and Safety of NNC-0156-0000-0009 During Surgical Procedures in Subjects With Haemophilia B [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of NNC-0156-0000-0009 during surgical procedures in people with Haemophilia B has …
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Trial Investigating Safety, Pharmacokinetics and Pharmacodynamics of Concizumab Administered Subcutaneously to Haemophilia A Subjects [Phase 1]
This Phase 1 trial update reports on the safety, pharmacokinetics and pharmacodynamics of subcutaneously administered concizumab in haemophi…
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CLINICAL_TRIALS research · 2017-05-24Clinical Trial Update: National Survey of People With Haemophilia in Portugal
This document reports the completion of a national survey of people with haemophilia in Portugal, sponsored by the University of Minho.
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Investigation of the Pharmacokinetics of NNC172-2021, at Two Different Dose Levels, in Healthy Japanese Subjects [Phase 1]
Phase 1 pharmacokinetic study of NNC172-2021 at two dose levels in healthy Japanese subjects; trial status completed.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Survey Evaluating the Psychosocial Effects of Living With Haemophilia
A completed clinical trial update describing a survey evaluating the psychosocial effects of living with haemophilia and related congenital …
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Safety and Pharmacokinetics of NNC 0129-0000-1003 in Subjects With Haemophilia A [Phase 1]
Phase 1 clinical trial evaluating the safety and pharmacokinetics of NNC 0129-0000-1003 in subjects with Haemophilia A has completed.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Comparison of the Action of Drugs in the Body and Safety of N8 and Advate® in Haemophilia A Subjects [Phase 1]
Phase 1 clinical trial evaluating pharmacokinetics and safety of N8 versus Advate in Haemophilia A subjects.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: A Single Dose Trial of Recombinant Factor VIII (N8) in Japanese Subjects With Haemophilia A: An Extension to Trial NN7008-3543 [Phase 1]
Phase 1 extension results from a single-dose trial of the recombinant Factor VIII (N8) in Japanese subjects with Haemophilia A.
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: Safety of 40K Pegylated Recombinant Factor IX in Non-Bleeding Patients With Haemophilia B [Phase 1]
Phase 1 safety study of a 40 kDa pegylated recombinant factor IX in non-bleeding patients with Haemophilia B has completed.
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Epidemiological Study on Haemophilia Care and Orthopaedic Status in Developing Countries
This completed epidemiological study sponsored by Novo Nordisk evaluates haemophilia care and orthopedic status in developing countries.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Pharmacokinetics of Single Bolus Dose of NovoSeven® in Paediatric and Adult Patients With Haemophilia A or B in a Non- Bleeding State [Phase 1]
This Phase 1 pharmacokinetic study evaluated a single bolus dose of NovoSeven in paediatric and adult patients with Haemophilia A or Haemoph…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: High Dose of Activated Recombinant Human Factor VII for Treatment of Mild/Moderate Joint Bleeds in Haemophilia Patients With Inhibitors [Phase 4]
Phase 4 trial update evaluating high-dose activated recombinant human factor VII to treat mild to moderate joint bleeds in haemophilia patie…
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CLINICAL_TRIALS trial_result · 2016-11-17Clinical Trial Update: Observational Patient Diary Study of Treatment Doses for Patients With Haemophilia With Inhibitors to Factors VIII and IX
This completed observational diary study collected data on treatment-dose patterns among patients with haemophilia A or B with inhibitors to…
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CLINICAL_TRIALS safety_alert · 2016-11-16Clinical Trial Update: Post-marketing Safety Surveillance of NovoSeven® in Patients With Haemophilia and Inhibitors by Means of the UK Haemophilia Database
This document reports post-marketing safety surveillance of NovoSeven in patients with haemophilia using data from the UK Haemophilia Databa…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Investigating Safety and Pharmacokinetics of 2 Different Single Doses of NNC128-0000-2011 in Haemophilia A or B Patients [Phase 1]
Phase 1 trial evaluating safety and pharmacokinetics of two single doses of NNC128-0000-2011 in haemophilia A or haemophilia B patients; the…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Safety and Mode of Action of a Single Dose and Multiple Doses of Long Acting Activated Recombinant Human Factor VII in Patients With Haemophilia A and B [Phase 1]
Phase 1 study evaluating safety and mode of action of a long-acting activated recombinant human factor VII in patients with haemophilia A or…
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CLINICAL_TRIALS research · 2016-03-14Clinical Trial Update: A Non-interventional Retrospective Study of the Current Treatment Practice in European Haemophilia Care
A non-interventional retrospective study evaluating current treatment practices for Haemophilia A and Haemophilia B in Europe.
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CLINICAL_TRIALS research · 2015-12-18Clinical Trial Update: Use of a TGA and TEM in the Assessment of the Efficacy of Treatment With APCC or rFVIIa
A clinical trial update on using thrombin generation assay (TGA) and thromboelastography (TEM) to assess the efficacy of APCC or recombinant…
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Project to Update the Study of Congenital Haemophilia in Spain
This document reports a completed clinical trial update in Spain for congenital haemophilia, involving Haemophilia A and Haemophilia B. The …
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CLINICAL_TRIALS research · 2015-10-21Clinical Trial Update: Validation of a Specific Measure for Assessment of Compliance With Treatment in Patients With Hemophilia
This document reports an update on a clinical trial validating a specific measure to assess treatment compliance in people with hemophilia.
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CLINICAL_TRIALS trial_result · 2015-04-16Clinical Trial Update: Observational Study on Safety of Room Temperature Stable NovoSeven® in Patients With Haemophilia A or B
This completed observational study assessed the safety of room-temperature-stable NovoSeven in patients with Haemophilia A or Haemophilia B.
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: A Trial Investigating the Pharmacokinetics and Pharmacodynamics of rFVIIa in Patients With Haemophilia A or B With or Without Inhibitors [Phase 1]
Phase 1 pharmacokinetics and pharmacodynamics study of recombinant factor VIIa in patients with Haemophilia A or Haemophilia B, with or with…
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CLINICAL_TRIALS research · 2014-11-14Clinical Trial Update: Observational Study Describing the Usual Clinical Practice Use of NovoSeven® in the Home Treatment of Joint Bleeds in Patients With Haemophilia A or B and Inhibitors
This completed observational study describes real-world, home-treatment use of NovoSeven for joint bleeds in patients with haemophilia A or …