Graves Ophthalmopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye Disease [Phase 2]
Phase 2 clinical trial update on tofacitinib for glucocorticoid-resistant moderate-to-severe Thyroid Eye Disease; the study is currently act…
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EMA approval · 2026-03-25EMA Authorised: Tepezza (teprotumumab) — Amgen Europe B.V.
The European Medicines Agency authorised Tepezza (teprotumumab) for Graves' ophthalmopathy, with Amgen Europe B.V. as the marketing authoriz…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Systemic Inflammation, Thyroid Autoimmunity and Neuroretinal Changes in Graves Disease
An ongoing clinical trial is investigating systemic inflammation, thyroid autoimmunity, and neuroretinal changes in Graves' disease and Grav…
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CLINICAL_TRIALS other · 2026-03-18Clinical Trial Update: Statin and Vitamin D Treatment in Patients With Thyroid Eye Disease [NA]
This clinical trial update describes a study evaluating statin plus vitamin D treatment in patients with Thyroid Eye Disease (Graves' ophtha…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease [Phase 2]
A Phase 2 study evaluating the efficacy and safety of LASN01 in Thyroid Eye Disease (Graves' ophthalmopathy) has completed and results are p…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated Ophthalmopathy
A clinical trial update describing an eye tracking study to assess eye movement and visual attention in patients with Graves' ophthalmopathy…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients With Graves Disease [NA]
A clinical trial is evaluating whether low-level light therapy improves ocular surface parameters in patients with Graves' ophthalmopathy an…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Anti-VEGF Therapy for Acute Thyroid Eye Disease [Phase 2]
A Phase 2 trial evaluating anti-VEGF therapy for acute thyroid eye disease has completed, potentially informing efficacy and safety signals.
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Exploring Immunological Markers Associated With Mental Fatigue in Graves' Disease
A clinical trial investigating immunological markers linked to mental fatigue in Graves' disease (including Graves' ophthalmopathy) that is …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease [Phase 2]
Phase 2 trial comparing sirolimus (rapamycin) against corticosteroids for thyroid-associated ophthalmopathy, currently recruiting.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Evaluation of the Efficacy and Safety Observation of IBI311 Treatment in Patients With Inactive TAO [Phase 4]
Phase 4 clinical trial evaluating the efficacy and safety of IBI311 for inactive Thyroid-associated ophthalmopathy (thyroid eye disease) is …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Bimatoprost as a Treatment for Graves' Orbitopathy [EARLY_Phase 1]
An early-phase Phase 1 trial from Johns Hopkins University is evaluating bimatoprost as a treatment for Graves' ophthalmopathy and is curren…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Multi-center Prospective Clinical Study on Glucocorticoid Pulse Therapy for Graves' Ophthalmopathy (GO) [NA]
A multi-center prospective clinical study is enrolling by invitation to evaluate glucocorticoid pulse therapy for Graves' ophthalmopathy.
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Glucocorticoids and Bone in Graves' Ophthalmopathy
Clinical trial update reporting results for a completed study on the impact of glucocorticoids on bone health in Graves' ophthalmopathy; res…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Hydroxychloroquine in Mild Graves' Orbitopathy [Phase 4]
Phase 4 clinical trial evaluating hydroxychloroquine for mild Graves' ophthalmopathy is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) [Phase 2, Phase 3]
An extension study of two doses of Linsitinib for Thyroid Eye Disease is in Phase 2/3 and currently recruiting, sponsored by Sling Therapeut…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Evaluation of the Efficacy and Safety of 3D Printing for Orbital Surgery. [NA]
A clinical trial is evaluating the efficacy and safety of 3D printing for orbital surgery and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Efficacy and Safety of SHR-1314 by Subcutaneous Injection in Active Moderate to Severe Graves' Orbitopathy Patients [Phase 2]
A Phase 2 trial evaluating SHR-1314 for active moderate-to-severe Graves' ophthalmopathy has been terminated, with the update covering its e…
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks (OraGO-1 Trial) [Phase 3]
The OraGO-1 trial is a Phase 3 study comparing one-week versus two-week orbital radiotherapy for Graves' ophthalmopathy and is currently rec…
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Treatment of Graves´ophthalmopathy with Simvastatin (GO-S) [Phase 3]
A Phase 3 clinical trial evaluating simvastatin for Graves' ophthalmopathy is currently recruiting.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Modified Orbital Decompression in the Treatment of Moderate-to-severe Grave's Ophthalmopathy [NA]
This document notes a clinical trial evaluating modified orbital decompression surgery for moderate-to-severe Graves' ophthalmopathy and ind…
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: A Randomized Clinical Trial of Intravenous Methylprednisolone With 2 Protocols in Patients With Graves Orbitopathy [Phase 4]
A Phase 4 randomized clinical trial is testing intravenous methylprednisolone using two protocols in Graves' ophthalmopathy. The study statu…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Study on Efficacy of Add on Selenium in Mild-to-moderate Graves Ophthalmopathy [NA]
This clinical trial is evaluating selenium as an add-on therapy for mild-to-moderate Graves' ophthalmopathy (thyroid eye disease); the study…
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CLINICAL_TRIALS trial_result · 2023-03-15Clinical Trial Update: Sirolimus for Graves' Orbitopathy (GO) [Phase 2]
Phase 2 clinical trial evaluating sirolimus for Graves' Ophthalmopathy is in a phase 2 study with unknown status.
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CLINICAL_TRIALS trial_result · 2023-03-15Clinical Trial Update: A Trial to Evaluate the Efficacy of Orbital Radiotherapy in Graves' Orbitopathy [Phase 4]
Phase 4 clinical trial evaluating the efficacy of orbital radiotherapy for Graves' ophthalmopathy (thyroid-associated ophthalmopathy).