Granulomatosis with Polyangiitis
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CLINICAL_TRIALS trial_result · 2026-08-06Clinical Trial Results: The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach [Phase 3]
Phase 3 trial results for prednisone in remission in granulomatosis with polyangiitis have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Study of One Protein Implicated in Wegener Disease [NA]
A completed clinical trial in Paris evaluated one protein implicated in Granulomatosis with polyangiitis (Wegener's granulomatosis).
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach [Phase 3]
Phase 3 clinical trial evaluating prednisone for remission in granulomatosis with polyangiitis has completed, under a Centers of Excellence …
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EMA trial_result · 2026-01-30EMA starts review of Tavneos, a medicine for rare autoimmune diseases GPA and MPA
The EMA has started a review of Tavneos (avacopan) after questions were raised about the integrity of data from the main pivotal study in gr…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis [Phase 2]
A Phase 2 clinical trial evaluating low-dose naltrexone for improving physical health in patients with vasculitis has completed.
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: One-Time DNA Study for Vasculitis
A University of Pennsylvania-led trial is recruiting for a one-time DNA study of various vasculitides, including eosinophilic granulomatosis…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Biosimilars of Rituximab in ANCA-associated Vasculitis Compared to the Originator
A completed clinical trial comparing rituximab biosimilars to the originator in ANCA-associated vasculitis, including granulomatosis with po…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Efficacy Study of Two Treatments in the Remission of Vasculitis [Phase 3]
Phase 3 trial update evaluating two treatments for inducing remission in granulomatosis with polyangiitis and microscopic polyangiitis; the …
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis)
A completed clinical trial investigates whether neutrophil levels can serve as prognostic indicators in granulomatosis with polyangiitis.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Comparison Study of Two Rituximab Regimens in the Remission of ANCA Associated Vasculitis [Phase 3]
Phase 3 trial comparing two rituximab regimens for maintaining or achieving remission in ANCA-associated vasculitis has completed.
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Mycophenolate Mofetil for Treatment of Relapses of Wegener's Disease or Microscopic Polyangiitis (MPA) [Phase 3]
Phase 3 trial evaluating mycophenolate mofetil for relapses of granulomatosis with polyangiitis (Wegener's granulomatosis) and microscopic p…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: PR3-AAV Resilient Remission or PRRR [Phase 2]
A Phase 2 trial of PR3-AAV Resilient Remission (PRRR) for ANCA-associated vasculitis, including granulomatosis with polyangiitis and microsc…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Abatacept for the Treatment of Relapsing, Non-Severe, Granulomatosis With Polyangiitis (Wegener's) [Phase 3]
This document reports the completion of a Phase 3 trial evaluating abatacept for relapsing, non-severe granulomatosis with polyangiitis (Weg…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: The Assessment of Prednisone In Remission Trial (TAPIR) - Patient Centric Approach [Phase 3]
The Phase 3 TAPIR trial evaluates prednisone in remission for granulomatosis with polyangiitis. The trial is currently active but not recrui…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Hydroxychloroquine in ANCA Vasculitis Evaluation [Phase 4]
Phase 4 trial update evaluating hydroxychloroquine for ANCA-associated vasculitis, including microscopic polyangiitis, eosinophilic granulom…
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CLINICAL_TRIALS trial_result · 2022-09-09Clinical Trial Update: A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis [Phase 3]
Phase 3 trial of avacopan (CCX168) in ANCA-associated vasculitis has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2022-08-25Clinical Trial Update: Study of IFX-1 to Replace Steroids in Patients With Granulomatosis With Polyangiitis and Microscopic Polyangiitis. [Phase 2]
Phase 2 clinical trial updating the use of IFX-1 as an alternative to steroids in Granulomatosis with Polyangiitis and Microscopic Polyangii…
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CLINICAL_TRIALS trial_result · 2022-07-06Clinical Trial Update: A Study Evaluating the Safety and Efficacy of Rituximab in Combination With Glucocorticoids in Participants With Wegener's Granulomatosis or Microscopic Polyangitis [Phase 4]
Phase 4 trial evaluating safety and efficacy of rituximab combined with glucocorticoids in Wegener's Granulomatosis (granulomatosis with pol…
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CLINICAL_TRIALS trial_result · 2022-05-26Clinical Trial Update: Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA [Phase 2]
Phase 2 safety and efficacy study of IFX-1 add-on to standard of care in GPA and MPA was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: Rituximab and Belimumab Combination Therapy in PR3 Vasculitis [Phase 2]
A Phase 2 trial evaluating Rituximab and Belimumab combination therapy for ANCA-associated vasculitis, including granulomatosis with polyang…
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CLINICAL_TRIALS trial_result · 2021-07-09Clinical Trial Update: Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA [Phase 4]
Phase 4 trial comparing tofacitinib vs methotrexate for maintained treatment of granulomatosis with polyangiitis.
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CLINICAL_TRIALS trial_result · 2020-05-26Clinical Trial Update: Plasma Exchange and Glucocorticoids for Treatment of Anti-Neutrophil Cytoplasm Antibody (ANCA) - Associated Vasculitis [Phase 3]
Phase 3 trial updating the use of plasma exchange and glucocorticoids for ANCA-associated vasculitis, with completion and results posted.
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: A Phase IIa Study of Intravenous Rituximab in Pediatric Participants With Severe Granulomatosis With Polyangiitis (Wegener's) or Microscopic Polyangiitis [Phase 2]
Phase IIa study evaluating intravenous rituximab in pediatric participants with granulomatosis with polyangiitis or microscopic polyangiitis…
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CLINICAL_TRIALS trial_result · 2018-08-17Clinical Trial Update: Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis [Phase 4]
A Phase 4 pilot study evaluating short-course glucocorticoids plus rituximab for ANCA-associated vasculitis has completed with posted result…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis [Phase 4]
The Phase 4 trial evaluating Rituximab for otolaryngologic manifestations of granulomatosis with polyangiitis has been terminated.