Gram-negative Bacterial Infections
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants [Phase 2]
This update reports the completion of a Phase 2 study evaluating the safety, tolerability, and pharmacokinetics of cefiderocol in hospitaliz…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Antibiotic Duration and Outcomes in High-Risk Febrile Neutropenia Patients [NA]
This clinical trial update describes ongoing research on optimal antibiotic duration and outcomes in high-risk febrile neutropenia patients,…
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EMA approval · 2025-12-18EMA Authorised: Fetcroja (cefiderocol sulfate tosilate) — Shionogi B.V.
EU authorisation of Fetcroja (cefiderocol) for Gram-negative bacterial infections, marking regulatory approval for this antimicrobial.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Extracorporeal Therapy and Therapeutic Drug Monitoring
Clinical trial update for a study evaluating extracorporeal therapy and therapeutic drug monitoring in ICU patients on ECMO or RRT with Gram…
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EMA approval · 2025-11-14EMA Authorised: Zavicefta (avibactam sodium;ceftazidime pentahydrate) — Pfizer Ireland Pharmaceuticals Unlimited Company
The EMA authorised Zavicefta (avibactam sodium and ceftazidime pentahydrate) for treatment of pneumonia, soft tissue infections, urinary tra…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Pharmacokinetics and Safety of HRS-8427 in Healthy Volunteers and in Patients With Impaired Renal Function [Phase 1]
Phase 1 data on the pharmacokinetics and safety of HRS-8427 in healthy volunteers and in patients with impaired renal function have been rep…
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CLINICAL_TRIALS trial_result · 2020-09-16Clinical Trial Update: Effect of Different Colistin Doses on Clinical Outcome of Pediatric Cancer Patients With Gram Negative Infections [Phase 4]
Phase 4 trial evaluating how different doses of colistin affect clinical outcomes in pediatric cancer patients with gram-negative infections…
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CLINICAL_TRIALS trial_result · 2019-09-20Clinical Trial Update: An Observational Pharmacokinetic Sudy of Ceftolozane-Tazobactam in Intensive Care Unit in Patients With and Without CRRT
An observational pharmacokinetic study evaluating ceftolozane-tazobactam in ICU patients with and without CRRT; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Piperacillin as a Part of Antibiotic Streamlining in the Intensive Care Unit
Completed clinical trial evaluating piperacillin as part of antibiotic streamlining in the intensive care unit for Gram-negative bacterial i…
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: A Study to Investigate the Intrapulmonary Lung Penetration of Nacubactam in Healthy Participants [Phase 1]
Phase 1 study evaluating intrapulmonary penetration of nacubactam in healthy participants, with the trial now completed.
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CLINICAL_TRIALS trial_result · 2016-08-04Clinical Trial Update: MED Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Intravenous WCK 5222 (Zidebactam and Cefepime) in Healthy Volunteers [Phase 1]
Phase 1 study of the WCK 5222 combination (Zidebactam and Cefepime) in healthy volunteers to evaluate safety, tolerability, and pharmacokine…
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Temocillin Pharmacokinetic in Hemodialysis [Phase 4]
Phase 4 study assessing the pharmacokinetics of temocillin in patients undergoing hemodialysis, in the setting of Gram-negative bacterial in…
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CLINICAL_TRIALS research · 2012-05-17Clinical Trial Update: Evaluation of Extended Intravenous of Beta-lactams in the Treatment of Serious Gram-negative Infections in Critically Ill Patients [NA]
Clinical trial update evaluating extended intravenous beta-lactam therapy for serious Gram-negative infections in critically ill patients. T…