Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2017-10-11Clinical Trial Update: Phase 2 Study of IDH305 in Low Grade Gliomas [Phase 2]
Phase 2 study of IDH305 for low-grade gliomas has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs) [Phase 2]
A Phase 2 clinical trial update evaluating weekly vinblastine in chemotherapy-naive children with progressive low-grade glioma.
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CLINICAL_TRIALS trial_result · 2017-08-25Clinical Trial Update: Sedatives' Effects on Neurological Function in Patients With Eloquent Area Glioma [NA]
A completed clinical trial at Beijing Tiantan Hospital studied how sedatives affect neurological function in patients with glioma. Results w…
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CLINICAL_TRIALS trial_result · 2017-08-04Clinical Trial Update: Image Guided Therapy in the Treatment of Gliomas [NA]
The NYU Langone Health trial on image-guided therapy for gliomas has been terminated.
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CLINICAL_TRIALS withdrawal · 2017-07-02Clinical Trial Update: A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors [Phase 1]
A Phase I pediatric trial of IMC-A12 (cixutumumab) in combination with temsirolimus for recurrent or refractory solid tumors has been withdr…
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CLINICAL_TRIALS trial_result · 2017-06-22Clinical Trial Update: Vaccination With Lethally Irradiated Glioma Cells Mixed With GM-K562 Cells in Patients Undergoing Craniotomy For Recurrent Tumor [Phase 1]
Phase 1 trial evaluating a vaccine made from lethally irradiated glioma cells mixed with GM-K562 cells in patients undergoing craniotomy for…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: A Phase II Study of Adjuvant Use of Anti-Epidermal Growth Factor Receptor EGFR-425 in High Grade Gliomas [Phase 2]
The document reports the completion of a Phase II trial evaluating adjuvant EGFR-425 therapy in high-grade gliomas.
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CLINICAL_TRIALS research · 2017-04-07Clinical Trial Update: 68Ga-NOTA-Aca-BBN(7-14) PET/CT in Patients With Primary Gliomas [EARLY_Phase 1]
This document reports an early-phase 1 clinical trial evaluating the diagnostic imaging agent 68Ga-NOTA-Aca-BBN(7-14) PET/CT in patients wit…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: 68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma [EARLY_Phase 1]
Clinical trial update for an early-phase 1 study of the Ga-68 labeled PET tracer 68Ga-BNOTA-PRGD2 in glioma diagnosis and evaluation, sponso…
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CLINICAL_TRIALS research · 2017-04-05Clinical Trial Update: Noninvasively Predicting Gene Status of Glioma
A clinical trial update describes a study aimed at noninvasively predicting the gene status of glioma.
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Treatment of High-grade Gliomas Using Hypofractionated Radiation Therapy -a Phase I Clinical Trial [NA]
A completed Phase I trial evaluating hypofractionated radiation therapy for high-grade gliomas to determine safety and the maximum tolerated…
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas [NA]
Terminated trial evaluating 18F-FDOPA PET/CT or PET/MRI for measuring tumors in patients with newly diagnosed or recurrent gliomas; results …
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CLINICAL_TRIALS trial_result · 2017-03-14Clinical Trial Update: Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis [Phase 1]
Phase 1 clinical trial update on an imaging probe for use in cell and gene therapy trials targeting brain neoplasms and rheumatoid arthritis…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors [Phase 1]
Phase 1 study of dendritic cell vaccine therapy with in situ maturation for pediatric brain tumors was terminated.
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Search for a Link Between Response to Treatment and Circulating Leucocytes in High Grade Glioma Patients [NA]
A completed clinical trial evaluating whether treatment response correlates with circulating leukocytes in high-grade glioma patients (gliob…
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CLINICAL_TRIALS research · 2017-02-20Clinical Trial Update: The Research on 89Zr-ABT806 PET Imaging in High Grade Glioma [NA]
Clinical trial update describing research on radiolabeled ABT-806 PET imaging with 89Zr in high-grade glioma, sponsored by Huashan Hospital.…
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CLINICAL_TRIALS research · 2017-01-20Clinical Trial Update: CCRT With Temozolomide Versus RT Alone in Patients With IDH Wild-type/TERT Promoter Mutation Grade II/III Gliomas [EARLY_Phase 1]
An early-phase trial update comparing concurrent chemoradiotherapy with temozolomide versus radiotherapy alone in patients with IDH-wildtype…
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CLINICAL_TRIALS research · 2017-01-16Clinical Trial Update: Identification of Clinically Occult Glioma Cells and Characterization of Glioma Behavior Through Machine Learning Analysis of Advanced Imaging Technology [NA]
This clinical trial update describes efforts to identify occult glioma cells and characterize glioma behavior using machine learning analysi…
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CLINICAL_TRIALS research · 2017-01-06Clinical Trial Update: 5-ALA in Recurrent Glioma [NA]
An update on a clinical trial evaluating 5-ALA (5-aminolevulinic acid) in recurrent glioma; the current phase and status are not specified.
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CLINICAL_TRIALS trial_result · 2017-01-05Clinical Trial Update: Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas [Phase 1]
A Phase I study at Johns Hopkins evaluated orally administered aminolevulinic acid for fluorescence-guided resection of malignant astrocytom…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Pilot Study Effect of Sulfasalazine on Glutamate Levels by(Magnetic Resonance Spectroscopy)MRS in Patients With Glioma [NA]
A pilot study evaluating the effect of sulfasalazine on brain glutamate levels in glioma patients using MR spectroscopy has completed. Resul…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Irinotecan in Treating Patients With Recurrent Glioma [Phase 2]
A Phase 2 trial of irinotecan in patients with recurrent glioma has completed; this update summarizes the trial status and results.
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas [Phase 1]
Phase 1 trial evaluating fluorodopa (FDOPA) PET/MRI for pre-operative evaluation of gliomas; the study status is terminated.
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062)
Clinical trial update for Temozolomide all-case surveillance (P05062) notes that the study status is COMPLETED and collected surveillance da…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma [Phase 1]
Phase 1 study of GDC-0084 in patients with progressive or recurrent high-grade glioma has completed. Indications studied include glioblastom…