Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently
This completed clinical trial evaluated functional MRI for mapping language areas in bilingual patients with glioma to aid pre-surgical plan…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors [Phase 1]
Phase 1 study evaluating panobinostat with stereotactic radiation therapy for brain tumors, including recurrent glioma, high-grade meningiom…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors [Phase 2]
Phase 2 trial of selumetinib in Neurofibromatosis type II–related tumors was terminated, with results posted in 2025; the study included ves…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Dapagliflozin Versus Dexamethasone Role in Pre-operative Management of Non- Diabetic Brain Tumor Patients [Phase 3]
Phase 3 clinical trial comparing dapagliflozin to dexamethasone for pre-operative management in non-diabetic patients with glioma; currently…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: A Nomogram for Predicting the Diagnosis of Central Malignant Tumors Based on Preoperative Clinical Characteristics and Laboratory Indicators:
A completed clinical trial evaluates a nomogram based on preoperative clinical characteristics and laboratory indicators to predict diagnose…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT) [Phase 1, Phase 2]
This update describes an ongoing Phase 1/Phase 2 trial evaluating the maximum tolerated dose, safety, and early efficacy of rhenium nanolipo…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Whole-Brain Tumor Burden Metrics with Inflammatory and Molecular Markers to Predict Postoperative Neurocognitive Decline in Glioma
This completed clinical trial evaluated whole-brain tumor burden metrics along with inflammatory and molecular markers to predict postoperat…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction [Phase 1]
Phase 1 clinical trial update of romidepsin for patients with lymphoma, chronic lymphocytic leukemia, or solid tumors with liver dysfunction…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Ivosidenib (AG-120) With Nivolumab in IDH1 Mutant Tumors [Phase 2]
Phase 2 trial evaluating Ivosidenib in combination with Nivolumab for IDH1-mutant tumors, including glioma, has completed with results poste…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas [Phase 1, Phase 2]
Clinical trial results update for a combined H3.3K27M peptide vaccine and nivolumab in children with newly diagnosed Diffuse Intrinsic Ponti…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors [NA]
This ClinicalTrials.gov update reports completion of an investigational 7T MRI imaging study for central nervous system tumors, with results…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Microdose Evaluation Study of ABY-029 in Recurrent Glioma [EARLY_Phase 1]
A microdose Phase 1 study evaluating ABY-029 in recurrent glioma has completed, with results posted on 2024-12-13.
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: MicroRNAs in Patients With Neurofibromatosis Type 1
Completed clinical trial evaluating microRNAs in patients with Neurofibromatosis Type 1, including glioma cases.
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma [Phase 1]
Phase 1 trial evaluating neo-adjuvant glioma lysate vaccines in WHO Grade II glioma has completed.
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Measuring Fatty Acid Oxidation in Gliomas Using 18F-FPIA PET/MRI
Completed clinical trial evaluating fatty acid oxidation in gliomas using the PET tracer 18F-FPIA with MRI. Results were posted on 2024-11-2…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Resting-State Functional MRI in Glioma Patients Before and After Surgery [NA]
This completed clinical trial used resting-state functional MRI to assess glioma patients before and after surgical resection.
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Brain Tumor Intraoperative Ultrasound Database
The Brain Tumor Intraoperative Ultrasound Database study has completed its clinical trial.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Blood and Cerebrospinal Fluid Metabolomic Profile in Glioma Patients
This completed trial reports the metabolomic profiles in blood and cerebrospinal fluid from patients with glioma, including glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: A Dose-Escalation Study in Participants With Recurrent Malignant Glioma [Phase 1]
Phase 1 dose-escalation trial in recurrent malignant glioma conducted by Eli Lilly has completed.
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: PARP Inhibition for Gliomas (PI-4G or π4g) [Phase 2]
Phase 2 trial of a PARP inhibitor for gliomas was terminated, with results posted in 2024, evaluating recurrent glioblastoma, recurrent astr…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma [Phase 1, Phase 2]
Regeneron’s cemiplimab (REGN2810) was studied in pediatric patients with relapsed/refractory solid tumors and CNS tumors, including a safety…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Combined Cytotoxic and Immune-Stimulatory Therapy for Glioma [Phase 1]
A Phase 1 clinical trial evaluating a combined cytotoxic and immune-stimulatory therapy for malignant glioma, including glioblastoma, has co…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating samotolisib in pediatric patients with relapsed or refractory tumors harboring TSC or PI3K/mTOR mut…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Dendritic Cell Vaccine for Patients With Brain Tumors [Phase 2]
Phase 2 trial of an autologous dendritic cell vaccine for brain tumors has completed enrollment and assessment.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors [Phase 2]
Phase 2 pediatric brain tumor trial evaluating MRI-guided laser heat ablation to disrupt the peritumoral blood-brain barrier in order to imp…