Glioma

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: [18F]FET PET for Characterization of Progressive or Recurrent Glioma From Treatment Related Changes

  Clinical trial update for a retrospective study using the radiotracer [18F]FET PET to characterize progressive or recurrent glioma after tre…

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors [EARLY_Phase 1]

  An early Phase 1 trial evaluates MeFAMP as an imaging agent for amino acid transport in brain tumors. The study targets recurrent glioma and…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma [Phase 1]

  Phase 1 trial evaluating the combination of ruxolitinib with radiation and temozolomide for grade III gliomas and glioblastoma; the study is…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Development of MRF for Characterization of Brain Tumors After Radiotherapy [NA]

  Development of a Magnetic Resonance Framework (MRF) to characterize brain tumors after radiotherapy, with recruitment ongoing at Case Compre…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations [Phase 2]

  This Clinical Trial Update reports on a Phase 2 study of olaparib in patients with advanced glioma, cholangiocarcinoma, or other IDH1/IDH2-m…

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• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy [NA]

  This clinical trial update describes evaluating step count monitoring as a measure of physical activity in patients with newly diagnosed gli…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients [NA]

  Clinical trial update for a simulation-based caregiving skills training program for family members of patients with high-grade glioma, curre…

• CLINICAL_TRIALS research · 2026-02-17
  Clinical Trial Update: Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation [Phase 1]

  A Phase 1 study evaluating orally administered AG-881 in patients with advanced solid tumors, including gliomas with IDH1 or IDH2 mutations;…

• CLINICAL_TRIALS research · 2026-02-17
  Clinical Trial Update: Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors

  This clinical trial update indicates the study analyzing cerebrospinal fluid leakage after intracranial tumor surgery is currently recruitin…

• CLINICAL_TRIALS research · 2026-02-12
  Clinical Trial Update: Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies [NA]

  This clinical trial update notes a Mayo Clinic-sponsored feasibility study on intraoperative microdialysis during neurosurgery for central n…

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Niraparib In Recurrent IDH 1/2 Gliomas [EARLY_Phase 1]

  An early-phase 1 trial update evaluating niraparib in recurrent IDH1/2-mutant gliomas, including low-grade and malignant gliomas.

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery [Phase 1, Phase 2]

  A Phase 1/2 clinical trial evaluating Panitumumab-IRDye800 for fluorescence-guided diagnosis in patients with malignant glioma undergoing su…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: Evaluation of the CONVIVO System [NA]

  The CONVIVO System is currently recruiting for a clinical trial evaluating its use in brain tumor surgery. It targets glioblastoma, glioma, …

• CLINICAL_TRIALS research · 2026-02-05
  Clinical Trial Update: Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors [Phase 1]

  A Phase 1 imaging trial evaluating a zirconium-89 labeled antibody (Zr-89 Crefmirlimab Berdoxam) for Immuno-PET imaging of resectable brain …

• CLINICAL_TRIALS research · 2026-02-04
  Clinical Trial Update: Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation [EARLY_Phase 1]

  Early-phase clinical trial evaluating contrast-enhanced ultrasound to improve visualization and border demarcation of glioma during neurosur…

• CLINICAL_TRIALS research · 2026-02-04
  Clinical Trial Update: CARv3-TEAM-E T Cells in Glioblastoma [Phase 1]

  A Phase 1 clinical trial evaluating CARv3-TEAM-E T cells for glioblastoma and malignant glioma is currently recruiting.

• CLINICAL_TRIALS research · 2026-02-04
  Clinical Trial Update: Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas [Phase 1]

  A Phase 1 study of DS-1001b in patients with IDH1-mutated gliomas is currently active but not recruiting.

• CLINICAL_TRIALS research · 2026-02-02
  Clinical Trial Update: Use of CEST (Chemical Exchange Saturation Transfer) Imaging in PET/MRI [NA]

  This clinical trial update describes the use of Chemical Exchange Saturation Transfer (CEST) imaging in PET/MRI for glioma and brain metasta…

• CLINICAL_TRIALS research · 2026-02-02
  Clinical Trial Update: Cognitive Changes of IDH-mutant and IDH-wildtype Glioma Patients After Chemoradiotherapy With Radiation Dose to the Resting State Networks

  This clinical trial is recruiting glioma patients with IDH-mutant and IDH-wildtype status to study cognitive changes after chemoradiotherapy…

• CLINICAL_TRIALS research · 2026-01-30
  Clinical Trial Update: Amino Acid Transporter System PET/CT Imaging in AATS-Related Diseases

  Ongoing clinical trial evaluating PET/CT imaging of the amino acid transporter system (AATS) in AATS-related diseases; currently recruiting.

• CLINICAL_TRIALS research · 2026-01-26
  Clinical Trial Update: Sequential Treatments or Combinations Including Dasatinib, Quercetin, Fisetin and/or Temozolomide for the Treatment of Previously Treated Glioma With Residual Disease [EARLY_Phase 1]

  EARLY_PHASE1 Mayo Clinic trial evaluating sequences or combinations of dasatinib, quercetin, fisetin and/or temozolomide for previously trea…

• CLINICAL_TRIALS research · 2026-01-23
  Clinical Trial Update: LITT Followed by Hypofractionated RT for Recurrent Gliomas [NA]

  Clinical trial evaluating laser interstitial thermal therapy (LITT) followed by hypofractionated radiation therapy for recurrent gliomas; re…

• CLINICAL_TRIALS research · 2026-01-20
  Clinical Trial Update: IL13Rα2 CAR-T for Patients With r/r Glioma [Phase 1]

  Phase 1 trial of IL13Rα2-targeted CAR-T therapy for recurrent or relapsed glioma; the study status is suspended.

• CLINICAL_TRIALS research · 2026-01-14
  Clinical Trial Update: BIO-SHORT: Biologically Guided Short-Course Hypofractionated RT for Poor-Prognosis GBM [Phase 2]

  BIO-SHORT is a Phase 2 trial evaluating biologically guided short-course hypofractionated radiotherapy for poorly prognostic glioblastoma. T…

• CLINICAL_TRIALS research · 2026-01-13
  Clinical Trial Update: Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors [Phase 1]

  Phase 1 clinical trial evaluating hyperpolarized carbon-13 pyruvate imaging to aid the diagnosis of glioma in patients with brain tumors; cu…