Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma [Phase 1]
This is a Phase 1 safety and dose-finding trial of GLIX1 in adults with recurrent or progressive high-grade glioma, currently not yet recrui…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies [Phase 4]
Phase 4 trial evaluating olutasidenib for drug-drug interaction in IDH1-mutant malignancies. The study is currently recruiting in AML, gliom…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications [Phase 1, Phase 2]
Clinical trial update for PLX038 in primary CNS tumors with MYC or MYCN amplification; Phase 1/2 studies are currently recruiting.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: 99mTc-1-thio-D-glucose SPECT/CT Versus 18F-Fluoroethyl-l-tyrosine PET/CT in Brain Tumor Imaging [NA]
A clinical trial update describes an active-not-recruiting study at Tomsk National Research Medical Center comparing 99mTc-1-thio-D-glucose …
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3 [Phase 1]
A Phase 1 study by Boehringer Ingelheim is testing how well different doses of BI 764532 are tolerated in DLL3-positive glioma patients; the…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Neuromodulation-Induced Cortical Prehabilitation in High Grade Glioma Near the Motor Pathway: Cortical Plasticity Assessed by Navigated Transcranial Magnetic Stimulation (nTMS) [NA]
A clinical trial evaluating neuromodulation to prehabilitate cortical function in patients with high-grade glioma near motor pathways, using…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Vorasidenib Guided by AGX PET in Recurrent/Low-grade Glioma [NA]
A clinical trial of Vorasidenib guided by AGX PET in recurrent and low-grade glioma is not yet recruiting, with Huashan Hospital listed as s…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A First-in-Human Study of the CIPHER System During Brain Surgery for Newly Diagnosed Glioma [NA]
First-in-human study of the CIPHER System during brain surgery for newly diagnosed glioma; the trial status is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: WBSI Guided Personalized Delivery of TTFields [NA]
This clinical trials entry reports that a Penn Medicine Abramson Cancer Center study evaluating WBSI-guided, personalized delivery of tumor-…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: ABY-029 Glioma Trial [Phase 1]
A Phase 1 clinical trial update for ABY-029 in glioma (intracranial tumor) is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Clinical, patHOlogical and Imaging Project of nEuro-oncology (HOPE)
HOPE (NCT05859659) is a clinical trial in neuro-oncology that is currently recruiting for brain cancers, including glioma and brain tumors. …
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Pembrolizumab, Olaparib, and Temozolomide for People With Glioma [Phase 2]
Phase 2 clinical trial update for pembrolizumab, olaparib, and temozolomide in glioma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance) [Phase 3]
Phase 3 trial SIGMA is investigating safusidenib as maintenance therapy for IDH1-mutant glioma and related astrocytoma/oligodendroglioma sub…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas [NA]
A clinical trial evaluating magnetic resonance elastography (MRE) to differentiate radiation necrosis from recurrent glioma in patients with…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
A pediatric cancer survivor study focusing on symptom cluster heterogeneity and gut microbiota mechanisms is currently recruiting, including…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Methimazole in Patients With Progressive Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating methimazole in progressive glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Investigating Mechanistic Predictors of Interpatient Variability and Temozolomide (TMZ) Induced Haematological Toxicity for Glioma Patients
A University College Cork trial is investigating mechanistic predictors of interpatient variability and Temozolomide-induced hematological t…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
This ClinicalTrials.gov entry notes molecular testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program and indicates on…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype [NA]
Clinical trial update: pembrolizumab is being studied in patients with hypermutator phenotype recurrent malignant glioma; the trial is curre…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG) [EARLY_Phase 1]
An early-phase imaging trial evaluating fluorescently labeled nivolumab-IRDye800 (Nivo800) for high-grade glioma, with the study currently n…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Monitoring of Neurological Symptoms, Treatment Tolerance, and Quality of Life Using the Resilience PRO Electronic Patient-reported Outcome Application in Patients With IDH-mutated Glioma [NA]
This is a clinical trial update describing monitoring of neurological symptoms, treatment tolerance, and quality of life in IDH-mutated glio…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Construction and Application of an IDH Mutation-Targeted PET/MRI Imaging Framework for Precision Diagnosis of Gliomas
This clinical trial aims to develop and apply an IDH mutation-targeted PET/MRI imaging framework to improve precision diagnosis of gliomas. …
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors
A clinical trial is assessing a self-administered remote neurological examination via a mobile app for patients with brain tumors; the study…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma [Phase 2]
Phase 2 clinical trial assessing the combination of All-Trans Retinoic Acid (ATRA) with a PD-1 inhibitor in recurrent IDH-mutant glioma; rec…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Tessa Jowell BRAIN MATRIX - Platform Study
Platform-level update for the Tessa Jowell BRAIN MATRIX platform study in glioma; the trial is currently recruiting.