Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2011-02-10Clinical Trial Update: Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy [Phase 3]
A Phase 3 trial evaluating an anti-tenascin radiolabeled antibody therapy for glioblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2011-02-02Clinical Trial Update: Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive Glioblastoma [Phase 3]
Phase 3 trial comparing imatinib mesylate with hydroxyurea versus hydroxyurea alone in temozolomide-resistant progressive glioblastoma; stud…
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CLINICAL_TRIALS trial_result · 2011-01-21Clinical Trial Update: A Phase II Exploratory, Multicentre, Open-label, Non-comparative Study of ZD1839 (Iressa) and Radiotherapy in the Treatment of Patients With Glioblastoma Multiforme [Phase 2]
Phase II multicenter, open-label, non-comparative study evaluating gefitinib (Iressa) with radiotherapy in patients with glioblastoma.
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CLINICAL_TRIALS trial_result · 2011-01-14Clinical Trial Update: Study of Aminolevulinic Acid to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain [Phase 1]
Phase 1 trial evaluating aminolevulinic acid to enhance visualization and surgical resection of malignant glial brain tumors; the study has …
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CLINICAL_TRIALS trial_result · 2010-11-18Clinical Trial Update: Temozolomide in Concomitant Radiochemotherapy Followed by Sequential Temozolomide Chemotherapy - Observational Program (Study P04816)
This clinical trial update reports results from an observational program evaluating temozolomide given with concomitant radiochemotherapy fo…
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CLINICAL_TRIALS trial_result · 2010-11-17Clinical Trial Update: Temozolomide in Elderly Patients With KPS < 70 [Phase 2]
Phase 2 trial of temozolomide in elderly glioblastoma patients with Karnofsky Performance Status < 70 has completed.
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CLINICAL_TRIALS research · 2010-10-22Clinical Trial Update: Combined Approach to Resection of Glioblastoma (GBM) by 5-Aminolevulinic Acid (5-ALA) and Intraoperative Magnetic Resonance Imaging (MRI)
Clinical trial update from the University of Zurich evaluating a combined approach to glioblastoma resection using 5-ALA fluorescence and in…
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CLINICAL_TRIALS trial_result · 2010-08-11Clinical Trial Update: Radiation Therapy, Arsenic Trioxide, and Temozolomide in Treating Patients With Newly Diagnosed High-Grade Glioma [Phase 1]
Phase 1 study evaluating the combination of radiation therapy, arsenic trioxide, and temozolomide in newly diagnosed high-grade glioma has c…
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CLINICAL_TRIALS research · 2010-07-23Clinical Trial Update: Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients [Phase 2]
Phase 2 clinical trial update comparing prolonged adjuvant temozolomide with a 'Stop & Go' strategy in glioblastoma patients.
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CLINICAL_TRIALS research · 2010-07-16Clinical Trial Update: Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating hyperbaric oxygen in combination with radiotherapy and temozolomide for adults with newly diagnosed gliobl…
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CLINICAL_TRIALS trial_result · 2010-05-17Clinical Trial Update: The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601) [Phase 2]
Phase 2 trial evaluating continuous 28-day temozolomide in patients with recurrent malignant glioma who failed the standard 5-day regimen; r…
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CLINICAL_TRIALS trial_result · 2010-04-02Clinical Trial Update: Post Marketing Surveillance: Newly Diagnosed Glioblastoma Multiforme Treated With Radiotherapy/Temozolomide and Adjuvant Temozolomide (Study P04739)
A post-marketing surveillance trial reports outcomes for newly diagnosed glioblastoma treated with radiotherapy and temozolomide, including …
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CLINICAL_TRIALS trial_result · 2010-03-10Clinical Trial Update: Study of Lenalidomide and XRT in Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 2]
A completed Phase 2 trial evaluating lenalidomide in combination with external beam radiation therapy for newly diagnosed glioblastoma multi…
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CLINICAL_TRIALS research · 2010-03-10Clinical Trial Update: A Comparison of FDG-PET Versus MRI Based Target Volume Delineation in Glioblastoma and the Role of FDG-PET/CT in the Alteration of MRI Based Target Volumes. [Phase 2]
This document provides an update on a Phase 2 trial comparing FDG-PET and MRI for delineating target volumes in glioblastoma and discusses h…
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CLINICAL_TRIALS trial_result · 2010-01-20Clinical Trial Update: A Phase II Study Of Gliadel, Concomitant Temozolomide And Radiation, Followed By Dose Dense Therapy With Temozolomide Plus Bevacizumab For Newly Diagnosed Malignant High Grade Glioma [Phase 2]
A Phase II study evaluates Gliadel wafers with temozolomide and radiation, followed by dose-dense temozolomide plus bevacizumab, for newly d…
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CLINICAL_TRIALS trial_result · 2009-11-25Clinical Trial Update: Phase I : Cediranib in Combination With Lomustine Chemotherapy in Recurrent Malignant Brain Tumour [Phase 1]
Phase I study evaluating cediranib in combination with lomustine for recurrent malignant brain tumors has completed (sponsored by AstraZenec…
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CLINICAL_TRIALS trial_result · 2009-11-18Clinical Trial Update: Chloroquine for Treatment of Glioblastoma Multiforme [Phase 3]
A Phase 3 clinical trial evaluating chloroquine for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2009-10-21Clinical Trial Update: TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating TP-38 toxin in pediatric patients with recurrent or progressive supratentorial high-grade glioma…
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CLINICAL_TRIALS trial_result · 2009-09-18Clinical Trial Update: Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM [Phase 2]
Phase 2 trial evaluating Gliadel Wafer with Temozolomide and radiation for newly diagnosed glioblastoma multiforme/high-grade glioma has bee…
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CLINICAL_TRIALS trial_result · 2009-07-23Clinical Trial Update: Pegylated Liposomal Doxorubicine and Prolonged Temozolomide in Addition to Radiotherapy in Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
Phase 1/2 trial of pegylated liposomal doxorubicin with prolonged temozolomide and radiotherapy in newly diagnosed glioblastoma has complete…
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CLINICAL_TRIALS research · 2009-07-17Clinical Trial Update: A Study of 131I-TM601 in Adults With Recurrent Malignant Glioma [Phase 1, Phase 2]
This clinical trial update describes a study of 131I-TM601 in adults with recurrent malignant glioma across Phase 1 and Phase 2, with the cu…
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CLINICAL_TRIALS research · 2009-07-17Clinical Trial Update: Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma [Phase 1]
This document reports a Phase 1 safety and dose-finding trial of TM-601 in adults with recurrent malignant glioma, including glioblastoma. T…
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CLINICAL_TRIALS trial_result · 2009-05-21Clinical Trial Update: Neuradiab® Combined With Bevacizumab (Avastin) Therapy in Patients With Recurrent Glioblastoma Multiforme [Phase 2]
Phase 2 trial evaluating Neuradiab in combination with bevacizumab for recurrent glioblastoma; the status is currently unknown.
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CLINICAL_TRIALS withdrawal · 2009-05-20Clinical Trial Update: Safety Study of the Combination of Tandutinib With Temozolomide and Bevacizumab After Radiation and Temozolomide in Patients With Newly Diagnosed With Glioblastoma Multiforme [Phase 1]
Phase 1 safety study of tandutinib in combination with temozolomide and bevacizumab for newly diagnosed glioblastoma; the trial has been wit…
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CLINICAL_TRIALS trial_result · 2009-04-03Clinical Trial Update: A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomas [Phase 1]
Phase 1 study evaluating the combination of motexafin gadolinium and temozolomide in malignant gliomas has completed.