Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: Niraparib Combined With Radiotherapy in rGBM [Phase 2]
Phase 2 clinical trial investigating niraparib combined with radiotherapy for recurrent glioblastoma.
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Temozolomide 12 Cycles Versus 6 Cycles of Standard First-line Treatment in Patients With Glioblastoma. [Phase 2]
Phase 2 trial comparing 12 cycles versus 6 cycles of standard first-line temozolomide treatment in glioblastoma; results completed with post…
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Pilot Study of Elemene in Treating Patients With Refractory Glioblastoma [Phase 2]
A Phase 2 pilot trial evaluating elemene for refractory glioblastoma is reported, with status currently unknown.
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CLINICAL_TRIALS trial_result · 2020-12-02Clinical Trial Update: Bevacizumab Beyond Progression (BBP) [Phase 2]
Phase 2 clinical trial update on Bevacizumab Beyond Progression in malignant glioma including glioblastoma and gliosarcoma; results posted a…
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CLINICAL_TRIALS trial_result · 2020-11-30Clinical Trial Update: Neoadjuvant PD-1 in Newly Diagnosed Glioblastoma [Phase 2]
A Phase 2 neoadjuvant PD-1 trial in newly diagnosed glioblastoma is being conducted, with status currently unknown.
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FDA approval · 2020-11-20FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for Temodar (temozolomide) filed by Merck Sharp & Dohme LLC, resulting in updated labeling to re…
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CLINICAL_TRIALS trial_result · 2020-11-17Clinical Trial Update: Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma [Phase 2]
Phase 2 trial investigating Optune plus Bevacizumab in bevacizumab-refractory recurrent glioblastoma; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2020-10-30Clinical Trial Update: Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating gefitinib with radiation therapy for glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update for rovalpituzumab tesirine in DL3-expressing advanced solid tumors shows termination with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-24Clinical Trial Update: Trial of Enzastaurin and Bevacizumab in Participants With Recurrent Malignant Gliomas [Phase 2]
Phase 2 trial evaluating enzastaurin with bevacizumab in recurrent glioblastoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-21Clinical Trial Update: HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial of HIF-2 alpha inhibitor PT2385 in recurrent glioblastoma completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab [Phase 2]
Phase 2 clinical trial evaluating oral pazopanib plus oral topotecan given in a metronomic antiangiogenic regimen for recurrent glioblastoma…
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CLINICAL_TRIALS trial_result · 2020-09-17Clinical Trial Update: A Trail of Fluzoparil in Combination With Temozolomide in Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating Fluzoparil in combination with temozolomide for recurrent glioblastoma.
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CLINICAL_TRIALS trial_result · 2020-09-14Clinical Trial Update: Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimen [Phase 2]
Phase 2 trial evaluating anlotinib in combination with dose-dense temozolomide for first recurrent/progressive glioblastoma after STUPP regi…
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CLINICAL_TRIALS trial_result · 2020-09-14Clinical Trial Update: HSRT and IMRT Chemoradiotherapy for Newly Diagnosed GBM [Phase 1, Phase 2]
Phase 1/2 trial update for HSRT and IMRT chemoradiotherapy in newly diagnosed glioblastoma multiforme, with unknown current status.
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CLINICAL_TRIALS trial_result · 2020-09-09Clinical Trial Update: Study of DC Vaccination Against Glioblastoma [Phase 2]
Phase 2 clinical trial update on dendritic cell vaccination for glioma/glioblastoma; current status is unknown.
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Bevacizumab w / Temozolomide PET & Vascular MRI For GBM [NA]
Clinical trial update for bevacizumab with temozolomide and PET/vascular MRI in recurrent glioblastoma; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-03Clinical Trial Update: Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma [Phase 1, Phase 2]
Clinical trial update for ABT-414 in Japanese subjects with malignant glioma (phase 1/2) completed.
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CLINICAL_TRIALS trial_result · 2020-09-02Clinical Trial Update: Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma. [Phase 3]
A Phase 3 trial comparing proton and heavy ion beam radiation with photon beam radiation for newly diagnosed glioblastoma is ongoing or pend…
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients [Phase 1, Phase 2]
Phase 1/2 study of enzastaurin in newly diagnosed glioblastoma multiforme and gliosarcoma completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-08-05Clinical Trial Update: Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors [Phase 2]
Phase 2 clinical trial update on stem cell transplant for high-risk CNS tumors including glioblastoma and astrocytoma; trial completed.
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Phase 2 Study of Sym004 for Adult Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 study of Sym004 in adults with recurrent glioblastoma has completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant Glioma [Phase 1]
Phase 1 trial update for EGFRvIII CAR T cells in newly diagnosed high-grade glioma (glioblastoma/gliosarcoma) has been terminated with resul…
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CLINICAL_TRIALS trial_result · 2020-07-20Clinical Trial Update: Study of Crenolanib in Recurrent/Refractory Glioblastoma With PDGFRA Gene Amplification [Phase 2]
Phase 2 clinical trial update for crenolanib in recurrent/refractory glioblastoma with PDGFRA amplification has completed.
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CLINICAL_TRIALS trial_result · 2020-06-29Clinical Trial Update: Trial of AEO in New Glioblastoma (GBM) [Phase 2]
Phase 2 trial update for AEO in glioblastoma, currently with unknown status.