Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-01-23Clinical Trial Update: Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma [Phase 2]
Phase 2 trial comparing etoposide plus cisplatin vs temozolomide in MGMT-unmethylated glioblastoma.
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CLINICAL_TRIALS trial_result · 2023-01-18Clinical Trial Update: Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients [Phase 1, Phase 2]
Phase 1/2 trial update evaluating MSC11FCD therapy for recurrent glioblastoma and related brain neoplasms.
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CLINICAL_TRIALS trial_result · 2023-01-13Clinical Trial Update: Radiotherapy Planning Using Fluciclovine PET in Patients With Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 clinical trial update evaluating radiotherapy planning with fluciclovine PET in patients with newly diagnosed glioblastoma.
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CLINICAL_TRIALS trial_result · 2023-01-11Clinical Trial Update: Pembrolizumab in Treating Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial of pembrolizumab in patients with recurrent glioblastoma (and recurrent gliosarcoma) has results posted, with the study curren…
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CLINICAL_TRIALS trial_result · 2022-12-29Clinical Trial Update: Phase II Trial of Low-Dose Whole Brain Radiotherapy With Concurrent Temozolomide and Adjuvant Temozolomide in Patients With Newly-Diagnosed Glioblastoma Multiforme [Phase 2]
Phase II trial investigating low-dose whole brain radiotherapy with concurrent and adjuvant temozolomide in newly diagnosed glioblastoma mul…
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CLINICAL_TRIALS trial_result · 2022-12-28Clinical Trial Update: B7-H3 CAR-T for Recurrent or Refractory Glioblastoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating B7-H3 CAR-T cells for recurrent or refractory glioblastoma is reported as ongoing with unknown status.
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CLINICAL_TRIALS trial_result · 2022-12-23Clinical Trial Update: LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas [Phase 1, Phase 2]
A clinical trial update evaluating Laser Interstitial Thermal Therapy (LITT) combined with early temozolomide in recurrent glioblastoma acro…
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CLINICAL_TRIALS trial_result · 2022-12-20Clinical Trial Update: A Safety Study of Sativex Compared With Placebo (Both With Dose-intense Temozolomide) in Recurrent Glioblastoma Patients [Phase 1, Phase 2]
Clinical trial update comparing Sativex with placebo (both with dose-intensive temozolomide) in recurrent glioblastoma; phases 1 and 2 have …
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CLINICAL_TRIALS trial_result · 2022-12-20Clinical Trial Update: A Safety Study of Sativex in Combination With Dose-intense Temozolomide in Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
Phase 1/2 safety study evaluating Sativex in combination with dose-intense temozolomide for recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2022-11-09Clinical Trial Update: Interest of Fluorescein in Fluorescence-guided Resection of Gliomas (FLEGME) [Phase 3]
Phase 3 clinical trial investigating the use of fluorescein for fluorescence-guided resection in gliomas has completed.
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CLINICAL_TRIALS trial_result · 2022-10-31Clinical Trial Update: A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme [Phase 3]
Phase III study investigating postoperative early temozolomide with the STUPP regimen for newly diagnosed glioblastoma multiforme; current s…
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CLINICAL_TRIALS trial_result · 2022-10-27Clinical Trial Update: 18F-Fluciclovine PET Imaging for Detecting High Grade Glioma Recurrence After Radiochemotherapy [Phase 3]
Phase 3 trial update evaluating 18F-Fluciclovine PET imaging to detect high-grade glioma recurrence after radiochemotherapy.
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CLINICAL_TRIALS trial_result · 2022-10-24Clinical Trial Update: Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma [Phase 2]
Phase 2 trial update for convection-enhanced delivery of MDNA55 in adults with recurrent or progressive glioblastoma; study completed with r…
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CLINICAL_TRIALS trial_result · 2022-10-20Clinical Trial Update: VXM01 Plus Avelumab Combination Study in Progressive Glioblastoma [Phase 1, Phase 2]
Clinical trial update on the combination of VXM01 with avelumab in recurrent glioblastoma across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2022-09-14Clinical Trial Update: Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagnosed Malignant Glioma [Phase 1, Phase 2]
Phase 1/2 study evaluating the PARP-1 inhibitor BSI-201 in newly diagnosed malignant glioma (glioblastoma) has completed.
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CLINICAL_TRIALS trial_result · 2022-09-09Clinical Trial Update: Regorafenib in Relapsed Glioblastoma [Phase 2]
Phase 2 trial update for regorafenib in relapsed glioblastoma (glioblastoma multiforme) has completed.
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CLINICAL_TRIALS trial_result · 2022-09-07Clinical Trial Update: Safety and Efficacy of Transient Opening of the Blood-brain Barrier (BBB) With the SonoCloud-9 [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing safety and efficacy of transient opening of the blood-brain barrier using SonoCloud-9 in adults with glio…
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CLINICAL_TRIALS trial_result · 2022-08-26Clinical Trial Update: NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing Surgery [EARLY_Phase 1]
A Phase 1 trial of NU-0129 in patients with recurrent glioblastoma or gliosarcoma undergoing surgery has completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2022-08-10Clinical Trial Update: Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma [Phase 2]
Phase 2 trial exploring laser interstitial thermal therapy with lomustine in recurrent glioblastoma or anaplastic astrocytoma; the study is …
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CLINICAL_TRIALS trial_result · 2022-08-09Clinical Trial Update: Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22 [Phase 1, Phase 2]
Phase 1/2 trial evaluating intraarterial cetuximab (Erbitux) and bevacizumab for relapsed/refractory intracranial glioma in patients under 2…
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CLINICAL_TRIALS trial_result · 2022-07-12Clinical Trial Update: Phase 2 Study of CAN008 in Subjects With GBM [Phase 2]
Phase 2 trial update for CAN008 in newly diagnosed glioblastoma.
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CLINICAL_TRIALS trial_result · 2022-07-01Clinical Trial Update: Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma [Phase 2]
Phase 2 trial assessing nivolumab, ipilimumab, and short-course radiotherapy in adults with MGMT-unmethylated glioblastoma; study completed …
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: A Study of the Effectiveness and Safety of Nivolumab Compared to Bevacizumab and of Nivolumab With or Without Ipilimumab in Glioblastoma Patients [Phase 3]
Phase 3 trial comparing nivolumab to bevacizumab and evaluating nivolumab with or without ipilimumab in recurrent glioblastoma, with results…
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant Glioblastoma [Phase 2]
Phase 2 trial evaluating avelumab with hypofractionated radiation therapy in IDH-mutant glioblastoma completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-06-23Clinical Trial Update: TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma [Phase 2]
Phase 2 trial update on TTFields combined with pulsed bevacizumab for recurrent glioblastoma has been terminated.