Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme [Phase 1]
This update reports the completion of a Phase I trial evaluating high-dose intravenous ascorbate (vitamin C) in patients with glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Study of MT027 in Patients with Recurrent or Progressive High-grade Glioma [Phase 1]
Phase 1 study evaluating MT027 in patients with recurrent or progressive glioblastoma. The trial is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations [Phase 1, Phase 2]
This clinical trial update reports results from a Phase 1/2 study of BGB-290 in combination with temozolomide in patients with recurrent gli…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 trial of Selinexor in combination with standard-of-care therapy for newly diagnosed or recurrent glioblastoma was terminated, wi…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor [Phase 1, Phase 2]
A clinical trial update describing radiodynamic therapy with Gliolan (5-ALA) for first recurrence glioblastoma, currently recruiting in Phas…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Physical Training in Glioblastoma Patients During Cytotoxic Therapy [NA]
A completed clinical trial evaluating physical training for glioblastoma patients undergoing cytotoxic therapy.
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme [Phase 2]
This update reports the completion of a Phase 2 trial evaluating hypofractionated stereotactic radiotherapy in recurrent glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Dendritic Cell Vaccination for Patients with Solid Tumors [Phase 1, Phase 2]
Phase 1/Phase 2 clinical study evaluating a dendritic cell vaccine in patients with solid tumors, including glioblastoma and renal cell carc…
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CLINICAL_TRIALS trial_result · 2024-12-02Clinical Trial Update: Efficiency of Vaccination with Lysate-loaded Dendritic Cells in Patients with Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 clinical trial evaluating a lysate-loaded dendritic cell vaccine in newly diagnosed glioblastoma patients; the study is currently ac…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma [Phase 1]
Phase 1 pilot study update of pembrolizumab in surgically accessible recurrent/progressive glioblastoma. The study investigates early immuno…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: NovoTTF-200A and Temozolomide Chemoradiation for Newly Diagnosed Glioblastoma [Phase 1]
Phase 1 trial evaluating NovoTTF-200A (Optune) with temozolomide chemoradiation for newly diagnosed glioblastoma. The study status is comple…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: WL276 CAR-T Cell Therapy for CD276 Positive Recurrent or Progressive Glioblastoma Patients [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating WL276 CAR-T cell therapy targeting CD276 in patients with recurrent or progressive glioblastoma; …
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Brain Tumor Intraoperative Ultrasound Database
The Brain Tumor Intraoperative Ultrasound Database study has completed its clinical trial.
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Blood and Cerebrospinal Fluid Metabolomic Profile in Glioma Patients
This completed trial reports the metabolomic profiles in blood and cerebrospinal fluid from patients with glioma, including glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: 18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients with EGFR Activated Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating Osimertinib with 18F-FDG PET to assess glucose utilization in EGFR-activated recurrent glioblastoma; the study has …
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Sonodynamic Therapy With ExAblate System in Glioblastoma Patients [Phase 2]
Phase 2 trial update shows completion of testing of sonodynamic therapy with the ExAblate system in glioblastoma patients.
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
A Phase 1 trial evaluating Lapatinib Ditosylate before surgical resection in adults with recurrent high-grade glioma has completed. The stud…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: PARP Inhibition for Gliomas (PI-4G or π4g) [Phase 2]
Phase 2 trial of a PARP inhibitor for gliomas was terminated, with results posted in 2024, evaluating recurrent glioblastoma, recurrent astr…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Study to Evaluate the Safety and Efficacy of ASC40 Tablets in Combination With Bevacizumab in Subjects With rGBM [Phase 3]
Phase 3 study evaluating ASC40 tablets in combination with bevacizumab for recurrent glioblastoma; the trial is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma [Phase 1]
Phase 1 trial evaluates genetically modified T-cells (CAR-T) in patients with recurrent or refractory malignant glioma. Results have been po…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma [Phase 1]
Amgen's Phase 1 study of AMG 596 in EGFRvIII-positive glioblastoma has been terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Glioblastoma [NA]
A completed clinical trial evaluating non-contrast perfusion using arterial spin-labeled MR imaging to assess therapy response in glioblasto…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma [Phase 1]
Phase 1 trial evaluating selinexor in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma (and gliosarcoma)…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Combined Treatment of Camrelizumab and Bevacizumab for Adult Patients with Recurrent Glioblastoma (GBM) [Phase 2]
A Phase 2 trial evaluating the combination of camrelizumab and bevacizumab in adults with recurrent glioblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Phase I Study of APX005M in Pediatric Central Nervous System Tumors [Phase 1]
Phase I study of APX005M in pediatric central nervous system tumors; the trial is active but not recruiting and results have been posted. Sp…