Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Personalized Functional Profiling in Metastatic Gastrointestinal Cancer or Recurrent Glioblastoma Patients in Luxembourg. [NA]
Completed clinical trial investigating personalized functional profiling for patients with metastatic gastrointestinal cancer or recurrent g…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas. [NA]
A completed clinical trial evaluating the safety of intensity-modulated radiotherapy with an inhomogeneous dose in patients with relapsed hi…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd [Phase 2]
Phase 2 trial evaluating talazoparib in combination with carboplatin for recurrent high-grade glioma with DDR deficiency has completed.
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: VB-111 in Surgically Accessible Recurrent/Progressive GBM [Phase 2]
Phase 2 trial of VB-111 in surgically accessible recurrent/progressive glioblastoma was terminated, with results posted in 2025.
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001 [Phase 1, Phase 2]
This Phase 1/2 trial evaluating concurrent radiotherapy, temozolomide, and BMX-001 for newly diagnosed high-grade glioma has completed enrol…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma [Phase 2]
A Phase 2 trial evaluating regorafenib in bevacizumab-refractory recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Contribution of Cerebral 18F-DOPA PET-CT Scan in High-grade Recurrent Gliomas [NA]
A completed clinical trial evaluated the usefulness of cerebral 18F-DOPA PET-CT imaging in patients with recurrent high-grade glioma.
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma [Phase 1]
Phase 1 trial evaluating tinostamustine with or without radiation therapy in newly diagnosed MGMT-unmethylated glioblastoma; the study has c…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent GBM [Phase 1]
A Phase 1 trial evaluating the safety, tolerability, and immunogenicity of EGFR(V)-EDV-Dox in subjects with recurrent glioblastoma and Grade…
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Avelumab in Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 2]
A phase 2 trial of the anti-PD-L1 agent avelumab in newly diagnosed glioblastoma multiforme has completed enrollment and posted results.
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: A Study Evaluating the Safety, Pharmacokinetic and Anti-tumor Activity of RO7428731 in Participants With Glioblastoma [Phase 1]
This entry summarizes the completion of a Phase 1 study evaluating the safety, pharmacokinetics, and anti-tumor activity of RO7428731 in pat…
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating the combination of ibudilast and temozolomide in newly diagnosed and recurrent glioblastoma has …
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-3 (UNITED-3) [NA]
UNITED-3 is evaluating unity-based MR-Linac guided adaptive radiotherapy for high-grade glioma (glioblastoma) in adults. The study is curren…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating pembrolizumab in combination with the IMA950 multipeptide vaccine and Poly-ICLC adjuvant for relapsing…
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Pilot Trial for Treatment of Recurrent Glioblastoma [EARLY_Phase 1]
A pilot early-phase 1 trial evaluating a treatment for recurrent glioblastoma is currently recruiting, sponsored by AHS Cancer Control Alber…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma [Phase 2]
Phase 2 trial evaluating Ad-RTS-hIL-12 plus Veledimex in combination with cemiplimab for recurrent or progressive glioblastoma was terminate…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Radiation/Temozolomide and Immunotherapy With Daratumumab to Improve Antitumor Efficacy in Glioblastoma [Phase 1, Phase 2]
A phase 1/2 study evaluating radiation/temozolomide with daratumumab immunotherapy for glioblastoma; the trial is currently active but not r…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma [Phase 1]
Phase 1 study evaluating Ad-RTS-hIL-12 in combination with Veledimex for glioblastoma and malignant glioma has completed enrollment, with re…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluated disulfiram with copper in combination with radiation therapy and temozolomide for newly diagnosed glioblastoma; …
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: A Nomogram for Predicting the Diagnosis of Central Malignant Tumors Based on Preoperative Clinical Characteristics and Laboratory Indicators:
A completed clinical trial evaluates a nomogram based on preoperative clinical characteristics and laboratory indicators to predict diagnose…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: [18F]FPIA PET-CT in Glioblastoma Multiforme (GBM)
Clinical trial update confirms completion of a study evaluating [18F]FPIA PET-CT imaging in glioblastoma.
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Evaluation of [18F]AlF-NOTA-PCP2 PET/CT for PD-L1 Detection in Malignant Tumors [Phase 1, Phase 2]
This clinical trial update describes evaluation of the PET tracer [18F]AlF-NOTA-PCP2 for PD-L1 detection across malignant tumors, including …
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma [Phase 2]
A Phase 2 trial (LUMINOS-101) evaluating Lerapolturev (PVSRIPO) in combination with pembrolizumab in recurrent glioblastoma has completed en…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma [Phase 2]
Phase 2 trial evaluating safety, pharmacokinetics, and efficacy of Paxalisib (GDC-0084) in newly diagnosed glioblastoma; trial completed wit…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Tryptophan Metabolism in Human Brain Tumors-Novocure
This clinical trial update reports on a completed study examining tryptophan metabolism in human brain tumors, with a focus on glioblastoma.