Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastoma [Phase 1]
The study evaluated how Brigimadlin (BI-907828) is taken up by glioblastoma tumors and identified the highest tolerated dose when given with…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating pembrolizumab in combination with the ATL-DC vaccine for surgically accessible recurrent glioblastoma; current stat…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: Analyzing Pulsed Reduced Dose Radiotherapy in Upfront Glioblastoma [Phase 2]
A Phase 2 clinical trial update on pulsed reduced dose radiotherapy used upfront for glioblastoma; the study is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6 [EARLY_Phase 1]
An early-phase 1 trial evaluating abemaciclib in combination with bevacizumab for recurrent glioblastoma with CDKN2A/B loss or CDK4/6 amplif…
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: PriCoTTF Study: TTFields Before and During Radiotherapy for Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
This update reports on a Phase 1/2 clinical trial evaluating Tumor Treating Fields (TTFields) therapy before and during radiotherapy for new…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma [Phase 2]
Open-label Phase 2 trial evaluating OKN-007 in combination with temozolomide for recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substudy to ATI001-102 [Phase 1]
A Phase 1 substudy evaluating Ad-RTS-hIL-12 with veledimex in combination with nivolumab for glioblastoma. The ATI001-102 substudy is comple…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields [Phase 2]
A Phase 2 study is evaluating whether topical clindamycin and triamcinolone can prevent skin-related side effects in patients with glioblast…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas [Phase 2]
Phase 2 clinical trial evaluating retifanlimab and epacadostat with radiation and bevacizumab in recurrent gliomas has completed. Results ha…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: RENEW: Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients. [Phase 1]
The Phase 1 feasibility trial (RENEW) evaluating CMV RNA-pulsed dendritic cell vaccines for newly diagnosed glioblastoma has been terminated…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases [NA]
This update notes a terminated clinical trial at the University of Southern California evaluating precise dynamic contrast-enhanced MRI (DCE…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma [Phase 2]
A Phase 2 trial evaluating spectroscopic MRI-guided radiation therapy planning for glioblastoma and gliosarcoma has completed with results p…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO)
The PEAR-GLIO trial evaluating an AI R&D tool for adult gliomas and other primary brain tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors [NA]
Completed clinical trial evaluating Blood-Brain Barrier Disruption (BBBD) for liquid biopsy in patients with glioblastoma or glioma, sponsor…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases [Phase 2]
Phase 2 trial evaluating crizanlizumab alone or with nivolumab for glioblastoma and melanoma brain metastases is currently recruiting at She…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001) [Phase 1]
Phase 1 trial update of belzutifan (PT2977, MK-6482) in patients with advanced solid tumors; study status is Phase 1 and not recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors [Phase 1, Phase 2]
A pharmacokinetic study evaluating the combination of lurbinectedin and irinotecan in selected solid tumors has completed (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels
This completed clinical trial evaluates BIOhabitats and biologically validates vascular habitats within Grade 4 astrocytoma (glioblastoma) a…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: Multicentre Validation of How Vascular Biomarkers From Tumor Can Predict the Survival of the Patient With Glioblastoma
A multicentre study validates vascular biomarkers from tumors as predictors of survival in glioblastoma. The trial has completed.
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: ALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade Gliomas
The ALBATROSS international multicenter study completed its prospective validation of imaging biomarkers calculated at vascular habitats of …
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Trial of C134 in Patients With Recurrent GBM [Phase 1]
Phase 1 clinical trial update for C134 in recurrent glioblastoma and related brain cancers reports results with results posted on 2025-07-03…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma [Phase 1]
Phase 1 clinical trial evaluating mycophenolate mofetil in combination with radiation therapy for glioblastoma and related astrocytomas; the…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Temozolomide Chronotherapy for High Grade Glioma [Phase 2]
Phase 2 trial of temozolomide chronotherapy for high-grade glioma, including glioblastoma, has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Metformin, Neo-adjuvant Temozolomide and Hypo- Accelerated Radiotherapy Followed by Adjuvant TMZ in Patients With GBM [Phase 2]
This Phase 2 clinical trial investigates metformin with neoadjuvant temozolomide and hypo-accelerated radiotherapy followed by adjuvant temo…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue [NA]
SonoClear is reporting completion of its clinical trial evaluating Acoustic Coupling Fluid (ACF) for brain-tissue–mimicking use in condition…