Glioblastoma
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Clinical Trial to Assess the Efficacy and Safety of 'Immuncell-LC' With Temozolomide in Newly Diagnosed Glioblastoma of Korea [Phase 3]
Phase 3 trial evaluating Immuncell-LC with temozolomide in newly diagnosed glioblastoma completed in Korea; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins. [EARLY_Phase 1]
An early-phase study evaluating the Ga-68 labeled FF58 radiotracer in selected solid tumors overexpressing integrins has been terminated.
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma [Phase 1]
Phase 1 study of pembrolizumab, vorinostat, and temozolomide in newly diagnosed glioblastoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma [Phase 1]
Phase 1 clinical trial evaluating repeated neural stem cell based virotherapy for newly diagnosed high-grade glioma.
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CLINICAL_TRIALS trial_result · 2025-10-06Clinical Trial Update: D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients [Phase 1, Phase 2]
This clinical trial update indicates ongoing Phase 1/2 studies of D2C7-IT and 2141-V11 for newly diagnosed MGMT unmethylated glioblastoma, c…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Pharmacoscopy for Patients With Refractory Primary Brain Tumors [Phase 2]
Phase 2 clinical trial update for pharmacoscopy in patients with refractory primary brain tumors, currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial [Phase 2]
This Phase IIc randomized feasibility pilot trial evaluated cognitive behavioral therapy for insomnia in patients with primary brain tumors …
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: G-CSF After Chemo-radiation in Patients With Glioblastoma [Phase 2]
This document reports a Phase 2 clinical trial evaluating the use of granulocyte colony-stimulating factor (G-CSF) after chemotherapy and ra…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating atezolizumab in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma has…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: hPG80 (Circulating Progastrin) as a Blood Biomarker for High-grade Glial Tumors
This update covers results from a completed clinical trial evaluating circulating progastrin (hPG80) as a blood biomarker for high-grade gli…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow [Phase 2]
Phase 2 clinical trial update for glioma using adaptive radiotherapy guided by an artificial intelligence workflow; the study is not yet rec…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMAS [Phase 3]
Phase 3 trial assessing medico-economic value of fluorescence-guided surgery to optimize glioblastoma resection has completed.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas
The clinical trial investigating microRNA-10b expression in glioma patients has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma [Phase 1]
Phase 1 clinical trial evaluating the safety and immunogenicity of a Personalized Genomic Vaccine in combination with Tumor Treating Fields …
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastoma [Phase 2]
Phase 2 clinical trial update evaluating ferumoxytol-enhanced MRI to monitor pembrolizumab response in glioblastoma; the study was terminate…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas [Phase 1]
A Phase 1 study reports on the safety and tolerability of Carboxyamidotriazole Orotate (CTO) in solid tumors and in combination with temozol…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression [Phase 2]
A Phase 2 safety study evaluating VAL-083 in combination with radiotherapy for newly diagnosed glioblastoma with unmethylated MGMT expressio…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM [Phase 3]
DelMar Pharmaceuticals' VAL-083 Phase 3 trial for recurrent glioblastoma (after temozolomide and bevacizumab) has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
Phase 1/2 trial assessing a PD-1 inhibitor combined with stereotactic radiation for recurrent glioblastoma; the study is currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: A Study of Abemaciclib in Recurrent Glioblastoma [Phase 2]
Results from a Phase 2 study of abemaciclib in recurrent glioblastoma have been posted.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Chlorpromazine and Standard of Care in Glioblastoma [Phase 1]
Phase 1 trial evaluating chlorpromazine in combination with standard of care for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma [EARLY_Phase 1]
Early-phase study evaluating the use of 18F-FDOPA PET imaging to plan surgery and radiation therapy for adults with newly diagnosed malignan…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting [Phase 2]
VAL-083 (dianhydrogalactitol) is being studied in MGMT unmethylated, bevacizumab-naive glioblastoma patients in the adjuvant or recurrent se…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
Kintara Therapeutics completed a Phase 1/2 safety study of VAL-083 in patients with recurrent malignant glioma, including glioma and gliobla…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102 [Phase 1]
Phase 1 substudy update evaluating Ad-RTS-hIL-12 with Veledimex in recurrent or progressive glioblastoma; results have been posted.