Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 1]
Phase 1 study evaluating the safety and dosing of gossypol (AT-101) with temozolomide with or without radiation therapy in newly diagnosed g…
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Pyrazoloacridine Followed by Radiation Therapy in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme [Phase 1, Phase 2]
A completed Phase 1/2 study evaluated pyrazoloacridine administered before radiation therapy in adults with newly diagnosed supratentorial g…
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM) [Phase 3]
Phase 3 trial evaluating NovoTTF-100A (Tumor Treating Fields) for recurrent glioblastoma multiforme has completed, per the update.
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: A Pilot Study of Using Video Images in Advance Care Planning in Malignant Glioma Patients [NA]
A pilot study conducted by Massachusetts General Hospital evaluated the use of video images in advance care planning for patients with malig…
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CLINICAL_TRIALS trial_result · 2012-04-26Clinical Trial Update: Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid [Phase 3]
Phase 3 trial update for fluorescence-guided resection of malignant gliomas using 5-aminolevulinic acid has completed.
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CLINICAL_TRIALS trial_result · 2012-04-17Clinical Trial Update: ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating ZD1839 (gefitinib) with oral irinotecan in young patients with refractory solid tumors, including glioblastoma, rha…
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CLINICAL_TRIALS trial_result · 2012-03-30Clinical Trial Update: Measuring Non-Enhancing Glioblastoma Progression
A completed clinical trial update describing methods for measuring progression in non-enhancing glioblastoma.
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CLINICAL_TRIALS trial_result · 2012-03-22Clinical Trial Update: Effect of Radiation Therapy Plus Temozolomide Combined With Cilengitide or Cetuximab on the 1-year Overall Survival of Patients With Newly Diagnosed MGMT-promoter Unmethylated Glioblastoma [Phase 2]
This Phase 2 trial evaluating radiation therapy and temozolomide with either cilengitide or cetuximab for newly diagnosed MGMT-promoter unme…
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CLINICAL_TRIALS trial_result · 2012-03-08Clinical Trial Update: Talampanel in Treating Patients With Recurrent High-Grade Glioma [Phase 2]
Phase 2 clinical trial of talampanel for recurrent high-grade glioma has completed.
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CLINICAL_TRIALS trial_result · 2012-03-06Clinical Trial Update: Erlotinib in Treating Patients With Progressive Glioblastoma Multiforme [Phase 1]
A Phase 1 trial evaluating erlotinib in patients with progressive glioblastoma multiforme has been terminated.
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CLINICAL_TRIALS trial_result · 2012-02-07Clinical Trial Update: The Effect of Monoclonal Vascular Endothelial Growth Factor (VEGF) Antibody (Bevacizumab) on Pituitary Function
A completed clinical trial investigating the effect of bevacizumab (VEGF antibody) on pituitary function in patients with colorectal cancer,…
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CLINICAL_TRIALS trial_result · 2012-02-06Clinical Trial Update: Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors [Phase 1, Phase 2]
This clinical trial update summarizes the results of a Phase 1/2 study evaluating lapatinib in pediatric patients with recurrent or refracto…
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CLINICAL_TRIALS trial_result · 2012-01-16Clinical Trial Update: Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM [Phase 1]
Phase 1 trial of dietary methionine restriction with temozolomide for recurrent glioblastoma was terminated.
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CLINICAL_TRIALS trial_result · 2012-01-11Clinical Trial Update: 6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients [Phase 2]
Phase 2 trial assessing a multi-drug regimen including 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine in patients…
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CLINICAL_TRIALS trial_result · 2012-01-06Clinical Trial Update: Evaluating Tumor Pseudoprogression With FLT-PET and MRI [EARLY_Phase 1]
An EARLY Phase 1 clinical trial evaluating tumor pseudoprogression using FLT-PET and MRI in glioblastoma was terminated.
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CLINICAL_TRIALS trial_result · 2011-12-30Clinical Trial Update: Phase III Trial of Primary Radio- or Chemotherapy in Malignant Astrocytoma of the Elderly [Phase 3]
A Phase III trial evaluating primary radiotherapy or chemotherapy in elderly patients with malignant astrocytoma (glioblastoma or anaplastic…
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CLINICAL_TRIALS trial_result · 2011-12-08Clinical Trial Update: Aspirin Prophylaxis for Venous Thromboembolism in Glioblastoma [Phase 2]
Phase 2 trial evaluating aspirin prophylaxis to prevent venous thromboembolism in glioblastoma was terminated, with results posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-10-14Clinical Trial Update: Phase 2 Study MPC-6827 for Recurrent Glioblastoma Multiforme [Phase 2]
Phase 2 study of MPC-6827 for recurrent glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2011-09-15Clinical Trial Update: Patupilone (EPO 906) in Patients With Recurrent or Progressive Glioblastoma [Phase 1, Phase 2]
This document reports on a Phase 1/2 trial of patupilone (EPO 906) in patients with recurrent or progressive glioblastoma, now completed.
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: Safety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma Multiforme [Phase 1]
Phase 1 trial evaluating the safety and radiation distribution of Cotara in patients with recurrent glioblastoma multiforme has been complet…
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: Temozolomide and Procarbazine With Cilengitide for Patients With Glioblastoma Multiforme Without Methylation of the MGMT Promoter Gene [Phase 2]
Phase 2 clinical trial evaluating a combination of temozolomide, procarbazine, and cilengitide in newly diagnosed MGMT unmethylated glioblas…
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CLINICAL_TRIALS trial_result · 2011-07-11Clinical Trial Update: Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas [Phase 1, Phase 2]
A pediatric Phase 1/2 trial evaluated gefitinib in combination with radiation therapy for newly diagnosed gliomas; the study completed and r…
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CLINICAL_TRIALS trial_result · 2011-06-06Clinical Trial Update: Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma [Phase 1]
Phase 1 imaging study evaluating how the IL13-PE38QQR conjugate distributes in adult patients with recurrent malignant glioma before and aft…
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CLINICAL_TRIALS trial_result · 2011-03-28Clinical Trial Update: Carboplatin Plus Irinotecan in Treating Patients With Glioblastoma Multiforme [Phase 2]
A Phase 2 trial evaluating carboplatin plus irinotecan for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2011-03-25Clinical Trial Update: Phase 1 Study of MPC-6827 and Carboplatin in Recurrent/Relapsed Glioblastoma Multiforme [Phase 1, Phase 2]
The document reports an early-phase (Phase 1/2) study evaluating MPC-6827 in combination with carboplatin for recurrent glioblastoma.